Interferon-Gamma Release Assays
Interferon Gamma Release Assays for Diagnosis of Pleural Tuberculosis: a Systematic Review and Meta Analysis
... the interferon gamma release assays for diagnosis of tuberculous pleural effusion using whole-blood (top) and pleural fluid (bottom) ...
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Systematic review and meta analysis on the utility of Interferon gamma release assays for the diagnosis of Mycobacterium tuberculosis finfection in children: a 2013 update
... of interferon-gamma release assays (IGRAs) for tuberculosis diagnosis in children yielded contrasting results, probably due to different inclusion/exclusion ...
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Serial interferon gamma release assays for latent tuberculosis in dialysis patients with end stage renal disease in a Korean population
... 13]. Interferon-gamma release assays (IGRAs) are useful tools for diagnosing LTBI, because they are more spe- cific, particularly in BCG vaccinated populations [14], and may identify some ...
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Interferon Gamma Release Assays for Latent Tuberculosis: What Are the Sources of Variability?
... Interferon gamma release assays (IGRAs) are blood-based tests intended for diagnosis of latent tuberculosis infection (LTBI). IGRAs offer logistical advantages and are supposed to offer ...
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Contribution of Interferon gamma release assays testing to the diagnosis of latent tuberculosis infection in HIV infected patients: A comparison of QuantiFERON TB Gold In Tube, T SPOT TB and tuberculin skin test
... The interferon-gamma release assays (IGRAs) measure T-cell release of interferon-γ (IFN-γ) following stimulation by antigens that are unique to ...these assays to detect ...
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Point Counterpoint: Should Interferon Gamma Release Assays Become the Standard Method for Screening Patients for Mycobacterium tuberculosis Infections in the United States?
... CMI assays that were available required a 48-h antigen stimulation step, followed by tritiated thymidine ...these assays difficult for clinical laboratories to ...CMI assays have been developed that ...
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Serial interferon gamma release assays during treatment of active tuberculosis in young adults
... To examine the potential of the IGRA as a surrogate for treatment response among young immunocompetent patients with TB, we evaluated the sequential changes in the interferon-gamma IFN-g[r] ...
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Comparison of two interferon gamma release assays in the diagnosis of Mycobacterium tuberculosis infection and disease in The Gambia
... ELISPOT assays for IFN-γ were performed as previously described ...wells. Assays were counted with an automated ELISPOT reader (AID-GmbH, Strasberg, ...
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Role of interferon gamma release assays in the diagnosis of pulmonary tuberculosis in patients with advanced HIV infection
... feron-gamma release assays cannot distinguish immune responses among patients with latent infection, prior active disease, and current active disease when performed using peripheral blood specimens ...
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Interferon-gamma release assays for the tuberculosis serial testing of health care workers: a systematic review
... “ interferon-gamma release assay ” OR “ IGRA ” OR "Quantiferon" OR "T-SPOT") AND ("health care workers" OR "healthcare workers" OR "health-care workers" OR ...
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Diagnosis of latent tuberculosis infection among HIV discordant partners using interferon gamma release assays
... Most studies in HIV positive individuals have shown a large number of indeterminate results and these have been associated with low CD4 counts [16,17]. Our study had a low incidence of indeterminate test results and most ...
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Circulating granulysin levels in healthcare workers and latent tuberculosis infection estimated using interferon gamma release assays
... with interferon gamma release in the present study, whereas GNLY expression levels and GNLY poly- morphisms were not, suggesting that GNLY may lack stability in TB infection, and its rates of ...
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Poor agreement between interferon gamma release assays and the tuberculin skin test among HIV infected individuals in the country of Georgia
... As recommended by the manufacturer and the U.S. Centers for Disease Control and Prevention (CDC), [17] the QFT-GIT result was considered positive if the interferon-gamma response to TB antigens minus the ...
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Short-Term Reproducibility of a Commercial Interferon Gamma Release Assay
... Interferon gamma release assays (IGRAs) have been shown to be sensitive and highly specific for the detection of immune memory against Mycobacterium ...continuous gamma ...
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Comparison of the Cytomegalovirus (CMV) Enzyme Linked Immunosorbent Spot and CMV QuantiFERON Cell Mediated Immune Assays in CMV Seropositive and Seronegative Pregnant and Nonpregnant Women
... two interferon gamma release assays (IGRA), the CMV enzyme- linked immunosorbent spot (ELISPOT) and CMV QuantiFERON assays, detecting CMV-specific CMI were ...These assays were ...
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IGRA tests perform similarly to TST but cause no adverse reactions: pediatric experience in Finland
... (IGRA): Interferon Gamma Release Assays; (TB): Tubercu- losis; (LTBI): Latent Tuberculosis Infection; (BCG): Bacille Calmette-Guérin; (SOP): Standard Operation procedure; Positive (PPV) and ...
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Using IFN-gamma release assay to confirm tuberculin skin test improves the screening of latent tuberculosis infection in Italian healthcare workers
... BCG, Bacillus Calmette-Guerin; HCWs, healthcare workers; IGRAs, Interferon gamma release assays; LTBI, latent tuberculosis infection; NTM, non- tuberculous mycobacteria; PPD, purified pr[r] ...
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Interferon-gamma release assay for the diagnosis of latent tuberculosis infection: a latent-class analysis
... Accurate diagnosis and subsequent treatment of latent tuberculosis infection (LTBI) is essential for TB elimination. However, the absence of a gold standard test for diagnosing LTBI makes assessment of the true ...
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Tuberculin skin test and ELISPOT/T. SPOT.TB in children and adolescents with juvenile idiopathic arthritis
... Adetifa IMO, Ota MOC, Jeffries DJ, Hammond A, Lugos MD, Donkor S, Patrick O, Adegbola RA, Hill PC: Commercial interferon gamma release assays compared to the tuberculin skin test for the[r] ...
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Detection of latent tuberculosis infection among migrant farmworkers along the US Mexico border
... There are two main diagnostic tools to detect LTBI: the tuberculin skin test (TST) and the interferon gamma release assays (IGRA) such as the Quantiferon TB gold- In-Tube (QFT-GIT). Both ...
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