interleukin-1 (IL-1)
Gonnermann, Claudia (2004): Der Interleukin-1-Genkomplex in der Schizophrenie. Dissertation, LMU München: Medizinische Fakultät
... des IL-1 nach Bindung an den Interleukin-1-Rezeptor zunächst zur Aktivierung der Serin-Threonin- Kinase ...wie IL-1 und IL-2 beteiligt ...effiziente IL-2-Synthese ...
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The involvement of proinflammatory cytokines in diabetic nephropathy: Focus on interleukin 1 (IL-1), interleukin 6 (IL-6), and tumor necrosis factor-alpha (TNF-α) signaling mechanism
... Interleukin 1 is one of proinflammatory cytokines which predicted to be involved in inflamma- tion-based disease e.g. sepsis, autoimmune disease, including DN. The two main ligands are IL-1α and ...
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Interleukin-1 associations in inflammatory bowel disease and the enteropathic seronegative spondylarthritis
... Proinflammatory cytokines, particularly tumor necrosis factor alpha (TNFa) and interleukin-1 (IL-1), are found to play a pivotal role during the acute phase response. Although treatment may ...
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Interleukin 1 stimulates fibroblasts to produce granulocyte macrophage colony stimulating activity and prostaglandin E2
... Granulocyte-macrophage colony-stimulating activity (GM-CSA) can be produced by a variety of normal cell types including mononuclear phagocytes, activated T lymphocytes, endothelial cells, and fibroblasts. Recent evidence ...
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Gene variants of interleukin-1 (il-1) and their role in development of osteoarthritis
... as IL-1 that is primarily synthesized by chondrocyte cells (Loughlin et ...2002). IL-1 super family consist of three key classes of interrelated cytokines viz IL-1α, IL-1β, and ...
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An Epstein-Barr Virus MicroRNA Blocks Interleukin-1 (IL-1) Signaling by Targeting IL-1 Receptor 1
... specifically interleukin-1  (IL-1  ...in interleukin signaling ...the IL-1 receptor 1 (IL1R1) as a direct target of ...disrupted IL-1  ...
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Investigating the role of interleukin-1 beta and glutamate in inflammatory bowel disease and epilepsy using discovery browsing
... that IL-1 beta inhibits ...that IL-1 beta inhibited potassium chloride-stimulated glutamate release in tis- sue from young (4 month) but not older (22 month) rats, and only in the presence of ...
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Mass Spectrometric Analysis of the Endogenous Type I Interleukin 1 (IL 1) Receptor Signaling Complex Formed after IL 1 Binding Identifies IL 1RAcP, MyD88, and IRAK 4 as the Stable Components
... I interleukin-1 (IL-1) receptor (IL-1RI) signaling complex using immunoprecipitation and tandem mass ...to interleukin-1 receptor-associated kinase ...of ...
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Role of Interleukin 1 Alpha (IL 1α) and Interleukin 1 Receptor Antagonist (IL 1RA) in Pathogenesis of Juvenile Idiopathic Arthritis and Adult Onset Rheumatoid Arthritis of Iraqi Patients
... and IL-1RA in both diseases with special reference to JIA, because the two cytokines have not been determined in Iraqi JIA ...patients. Interleukin-1 is an inflammatory cytokine that has multiple ...
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Differences in the Levels of Interleukin-1β (IL-1β) and Interleukin-1 Receptor Antagonist (IL-1ra) in Children with Status Epilepticus and Febrile Seizure
... that IL-1ra levels were ele- vated in all groups (reference value ...ever, IL-1ra levels in the febrile seizure group were sig- nificantly higher than in the status epilepticus ...of IL-1ra levels ...
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Interleukin 1 (IL 1) gene expression, synthesis, and effect of specific IL 1 receptor blockade in rabbit immune complex colitis
... h. IL-1 alpha levels were highly correlated with inflammation (r = ...specific IL-1 receptor antagonist (IL-1 ra) before and during the first 33 h after the administration of ...
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Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells
... monocyte-derived IL-1 (T-lymphocyte activation and human synovial cell prostaglandin E2 and collagenase production) ...human IL-1 was expressed, purified, and ...human IL-1 ...
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Distribution of interleukin-1 receptor complex at the synaptic membrane driven by interleukin-1β and NMDA stimulation
... in IL-1RI receptors at the postsynaptic site may be due to new synthesis and delivery of recep- tors from the endoplasmic reticulum, or to lateral diffu- sion from adjacent compartments [19,21], and this was ...
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Immunomodulatory factors gene polymorphisms in chronic periodontitis: an overview
... whereas IL-1β act as an extracellular ...of IL-1α, IL-1β and also IL-1/IL-receptor antagonist (RA, anti in- flammatory cytokine) have been increased in patients with periodontal ...
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Signal transduction pathways activated by the IL 1 receptor family: ancient signaling machinery in mammals, insects, and plants
... Abstract: Interleukin-1 (IL-1) is a central regula- tor of the immune and inflammatory ...of IL-1 receptors and IL-1 signal transduc- ...I IL-1 ...
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T lymphocyte reactivity and antibody response to a synthetic peptide (glutamic acid alanine tyrosine) as a marker for disease resistance in chickens
... Accessory cell and interleukin-mediated interactions in an immune response leading to antibody production Ag, antigen; APC, antigen presenting cell; IL-1, interleukin 1; IL-2, interleuki[r] ...
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Increased Production of Proinflammatory Cytokines following Infection with Porcine Reproductive and Respiratory Syndrome Virus and Mycoplasma hyopneumoniae
... cytokines interleukin-1 (IL-1) ( ␣ and  ), IL-6, IL-8, IL-10, IL-12, and tumor necrosis factor alpha (TNF- ␣ ) in pulmonary alveolar macrophages (PAMs) was ...
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Immunotherapy of brain metastases: breaking a “dogma”
... factor-1; IL: Interleukin; IL-10: Interleukin-10; IL-1 β : Interleukin-1 β ; IL- 23: Interleukin-23; IL-6: Interleukin-6; ...
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Assessment of Pro-Inflammatory Cytokines Level in Stored Blood for Transfusion in Port Harcourt, Nigeria
... as interleukin 1 beta (IL-1β), interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) released by white ...
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Determination of Changes in Blood Biomarker Levels in Antipsychotic Polypharmacy and Aripiprazole Monotherapy in Patients With Long-term Schizophrenia
... as Interleukin 2 (IL-2) and Inter- leukin 6 (IL-6) are altered in the serum of schizophrenic patients with an upstream regulation of inflammatory cytokines and some of their receptors, such as ...
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