Interleukin-10
A Survey on the Role of Interleukin-10 in Breast Cancer: A Narrative
... The role of the estrogen receptor in cytokine production and regulation is not known (61). Interleukin-10 has been found in both tumor cell cytoplasm and stroma. Moreover, cytokines, including IL-10, ...
8
A homolog of interleukin-10 is encoded by the poxvirus orf virus.
... A gene encoding a polypeptide with homology to interleukin-10 (IL-10) has been discovered in the genome of orf virus (OV) strain NZ2, a parapoxvirus that infects sheep, goats, and humans. The ...
5
Parasitemia Induces High Plasma Levels of Interleukin-17 (IL-17) and Low Levels of Interleukin-10 (IL-10) and Transforming Growth Factor- (TGF-) in Pregnant Mice Infected with Malaria
... malaria. Interleukin 10 (IL-10) is a key cytokine that is involved in both protection and immuno-pathology during malaria ...(18). Interleukin-10 has previously been found to be ...
8
Interleukin-10 Family and Tuberculosis: An Old Story Renewed
... The interleukin-10 (IL-10) family of cytokines consists of six immune mediators, namely IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. IL-10, IL-22, IL-24 and IL-26 are critical for the ...
8
Association between interleukin 1β and interleukin 10 concentrations: a cross-sectional study in young adolescents in Taiwan
... Background: In adults, low circulating interleukin 10 (IL10) has been associated with obesity and type 2 diabetes. However, studies investigating IL10 in overweight and obese children have yielded ...
10
Koi Herpesvirus Encodes and Expresses a Functional Interleukin-10
... Koi herpesvirus (KHV) (species Cyprinid herpesvirus 3) ORF134 was shown to transcribe a spliced transcript encoding a 179- amino-acid (aa) interleukin-10 (IL-10) homolog (khvIL-10) in koi fin ...
9
Potent Immunosuppressive Activities of Cytomegalovirus- Encoded Interleukin-10
... Cytomegalovirus (CMV) has highly evolved mechanisms for avoiding detection by the host immune system. Recently, in the genomes of human and primate CMV, a novel gene comprising segments of noncontiguous open reading ...
9
Original Article Aqueous nasal spray of chitosan oligosaccharide ameliorates perennial allergic rhinitis by affecting serum levels of interleukin-6 and interleukin-10
... Abstract: Background and objective: Chitosan oligosaccharide (COS) is widely used to attenuate inflammation. How- ever, its potential to suppress allergic rhinitis remains unknown. Methods: A 24-week study of patients ...
10
Interleukin-10 facilitates the selection of patients for systemic thrombolysis
... of interleukin (IL)-6 and tumour necrosis factor (TNF)-α were measured using an immunodiagnostic IMMULITE 1000 System (Diagnostic Products Corporation, California, ...
7
Original Article Effects of nicorandil on cardiac function and interleukin-10 and interleukin-17 levels in elderly patients with chronic heart failure
... increase resting potential, shorten the action potential cycle, depolarize mitochondrial mem- branes, promote the production of ATP, and pre- vent cardiomyocyte apoptosis, thereby alleviat- ing myocardial damage and ...
8
Prevention of arthritis by interleukin 10-producing B cells
... concept that CD40 might have a role in a negative feed- back loop that in this model would lead to the control of Th1 differentiation by B cells. However, the fact that direct stimulation of purified B cells with antigen ...
13
Interleukin-10 inhibits interleukin-1β production and inflammasome activation of microglia in epileptic seizures
... in 10 min; 3, more than 20 body jerks in 10 min; 4, clonic forelimb convulsions; 5, generalized clonic convulsions with episodes of rearing and falling down; 6, generalized convulsions with tonic extension ...
13
Effects of Interleukin-4 or Interleukin-10 gene therapy on trinitrobenzenesulfonic acid-induced murine colitis
... There may be three potential explanations why the combination treatment has less effect as a therapeutic strategy, i.e., i) The administered dose of the combination (half of each single dose) may not reach the effective ...
7
Accelerated Prion Disease in the Absence of Interleukin-10
... (59). In summary, there is an increasing amount of evidence that reveals a role for proinflammatory cytokines in initiating and maintaining the pathology of prion disease. Our data suggest that IL-10 plays a ...
11
Interferon gamma differentially regulates interleukin 12 and interleukin 10 production in leprosy
... The ability of monocytes to influence the nature of the T cell response to microbial pathogens is mediated in part by the release of cytokines. Of particular importance is the release of IL-12 and IL-10 by cells ...
7
Role of interleukin 10 in specific immunotherapy
... Recently, we demonstrated that BV-SIT induces a state of epitope-specific anergy in T cells against PLA, the major aller- gen of BV (30). The anergy, which could also be generated in T cell clones after peptide-ligand ...
10
Local delivery of adenoviral vectors encoding murine interleukin 10 induces colonic interleukin 10 production and is therapeutic for murine colitis
... hypothesised that the neutralising antibody response to AdvmuIL-10 vectors would be diminished, as the protein encoded for by this virus will act to suppress both T cell acti- vation and antigen presentation. A ...
13
Polymorphisms in interleukin-6 and interleukin-10 may be associated with risk of preeclampsia.
... Previous investigations have tested the association between IL-10 gene polymorphisms and preeclampsia development, but with conflicting results (Stonek et al., 2008; Vural et al., 2010; Valencia Villalvazo et al., ...
8
Evaluation of Interleukin-10 (G-1082A) Promoter Polymorphism in Preeclampsia
... IL-10 promoter SNP genotype frequencies ap- pear to exhibit different distributions according to ethnicity. The present study revealed no associa- tion of IL-10 -1082 polymorphism in patients with ...
5
Potential role for interleukin 10 in the immunosuppression associated with kala azar
... immunosuppressive factors, a series of T cell lines and clones were established from patients with acute kala azar, from patients after chemotherapy for kala azar, and from skin test-positive adults from the same endemic ...
8