interleukin-17
Selectively High Levels of Serum Interleukin 17 in a Newborn Infant With Progressive Severe Cholestasis
... We present here the unusual case of a male newborn infant who showed progressive severe cholestasis. The infant’s gestational age was 37 weeks, and his birth weight was 2134 g. His serum level of direct bilirubin ...
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Expression of Interleukin-17 associated with disease progression and liver fibrosis with hepatitis B virus infection: IL-17 in HBV infection
... Background/objectives: As a proinflammatory cytokine, interleukin-17 (IL-17) contributes to the inflammation of many autoimmune diseases. We examined IL-17 levels in serum and tissues from ...
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Polymorphism of interleukin-17 and its relation to mineral density of bones in perimenopausal women
... that interleukin 17 is produced not only by the Th17 lymphocytes but also other cell types, including macrophages, neutrophils and mast cells ...[2]. Interleukin 17 shows strong ...
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Human colon carcinogenesis is associated with increased interleukin-17-driven inflammatory responses
... cytokine interleukin-17 (IL-17 or IL-17A) has been shown to play a critical role in colon carcinogenesis in mouse ...in 17 cases of human colon adenocarcinomas, 16 cases of human normal colon ...
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The role of T cell interleukin 17 in conducting destructive arthritis: lessons from animal models
... Interleukin-17 (IL-17) is a T cell cytokine spontaneously produced by cultures of rheumatoid arthritis (RA) synovial membranes. High levels have been detected in the synovial fluid of patients with ...
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Effect of Apus Bamboo Shoot Extract on Total Interleukin 17 and Leukocyte at Atherosclerosis Process
... 2011). Interleukin-17 has the potential to cause the incidence of acute coronary syndromes through 3 pathways, ie 1) in macrophages, produced cytokines / chemokines, and foam cell formation; 2) in smooth ...
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New insight into the functions of the interleukin 17 receptor adaptor protein Act1 in psoriatic arthritis
... In 2010, a new association between the tumor necrosis factor receptor-associated factor 3-interacting protein 2 (TRAF3IP2) gene and the immune-mediated diseases psoriatic arthritis (PsA) and psoriatic vulgaris (PsV) was ...
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Butyrate inhibits interleukin-17 and generates Tregs to ameliorate colorectal colitis in rats
... helper 17 (Th17) cells are unique pro- inflammatory Th cells identified by retinoic acid receptor-related orphan receptor gamma t (ROR γ t) and interleukin-17 (IL-17) ...ing ...
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EVALUATING LEVELS OF INTERLEUKIN 1Β AND INTERLEUKIN 17 IN RHUMATOID ARTHRITIS PATIENTS IN THI QAR PROVINCE
... the interleukin 17 (IL-17) cytokine family, including IL-17A (commonly referred to as IL-17), IL-17B, IL-17C, IL-17D, IL-17E (also known as IL-25) and ...
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Interleukin-17 and type 17 helper T cells in cancer management and research
... helper 17 (Th17) cells have been frequently detected in the tumor microenvironment of many malignancies, but their clinical implications remain largely ...unknown. Interleukin-17 (IL-17) ...
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LEVELS OF INTERLEUKIN 17 AND VITAMIN D AND THEIR CORRELATION IN VIRAL HEPATITIS PATIENTS
... The interleukin 17 is usually linked to tissue damage in autoimmune disorders and bacterial and fungal ...of Interleukin-17 and Vitamin D3 (as Calcitriol) in viral hepatitis patients and ...
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<p>Role of maternal serum interleukin 17 in preeclampsia: diagnosis and prognosis</p>
... Background: Immunological factors play a unique role in the setting of preeclampsia; there is a rising debate about the performance of interleukin 17 (IL-17) as in fl ammatory mediator in its ...
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Association between interleukin-17 gene polymorphisms and the risk of laryngeal cancer in a Chinese population.
... 2011). Interleukin 17 (IL-17) was originally cloned from the cDNA sequence of a hybrid rodent T cell in 1993 and named CTLA-8 by Rouvier (Singh et ...
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Targeting of interleukin-17 in the treatment of psoriasis
... We performed a systematic review of all studies investigat- ing the efficacy and safety of brodalumab, secukinumab, and ixekizumab for the treatment of psoriasis. The PubMed database was systematically searched using ...
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Biology of recently discovered cytokines: Interleukin 17 – a unique inflammatory cytokine with roles in bone biology and arthritis
... at least partially controlled at the level of mRNA stability, because AU-rich elements exist in the 3′-untranslated region that could target the transcript for rapid degra- dation [2,27,28]. Clearly, much still remains ...
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Serum Interleukin-17 Level in Patients with Rheumatoid Arthritis and its Relation to Disease Activity
... The present study clarified that there was a significant difference between the studied groups regarding the level of IL-17. IL-17 level was significantly higher in the RA group (226.6±215.6 pg/ml) than the ...
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ROLE OF INTERLEUKIN-17 IN THE DEVELOPMENT OF HEPATOCELLULAR CARCINOMA IN HEPATITIS C VIRUS LIVER CIRRHOSIS
... Seetharam et al., 2011 described different results; a transient IL-17 and IL-10 response may also result in spontaneous viral clearance followed by a subsequent reactivation of Th1 immunity, which prevented ...
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MicroRNA 146a expresses in interleukin 17 producing T cells in rheumatoid arthritis patients
... RA patients there is no report that analyzes miRNAs associated with IL-17 producing T cells. Changsheng Du et al. reported that miR-326 regulates Th-17 differentia- tion and associated with the pathogenesis ...
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Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor
... Phosphorylation of IL-17RA is linked to degradation of IL-17RA. We have demonstrated that total IL-17RA protein levels are increased when IL-17RA phosphorylation is reduced by LiCl and insulin through inhibiting GSK3 ...
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Original Article Increased expression of interleukin-17 is associated with macrophages in chronic immune thrombocytopenia
... It remains difficult to identify which cells secrete or express IL-17 in the BM of patients with chronic ITP because we did not examine mRNA or perform double staining. However, the pres- ence of IL-17 ...
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