Interleukin 17 (IL-17)
Human colon carcinogenesis is associated with increased interleukin-17-driven inflammatory responses
... cytokine interleukin-17 (IL-17 or IL-17A) has been shown to play a critical role in colon carcinogenesis in mouse ...in 17 cases of human colon adenocarcinomas, 16 cases of human normal colon ...
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Targeting of interleukin-17 in the treatment of psoriasis
... We performed a systematic review of all studies investigat- ing the efficacy and safety of brodalumab, secukinumab, and ixekizumab for the treatment of psoriasis. The PubMed database was systematically searched using ...
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Polymorphism of interleukin-17 and its relation to mineral density of bones in perimenopausal women
... that interleukin 17 is produced not only by the Th17 lymphocytes but also other cell types, including macrophages, neutrophils and mast cells ...[2]. Interleukin 17 shows strong ...
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<p>Role of maternal serum interleukin 17 in preeclampsia: diagnosis and prognosis</p>
... Background: Immunological factors play a unique role in the setting of preeclampsia; there is a rising debate about the performance of interleukin 17 (IL-17) as in fl ammatory mediator in its ...
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Interleukin-17 and type 17 helper T cells in cancer management and research
... helper 17 (Th17) cells have been frequently detected in the tumor microenvironment of many malignancies, but their clinical implications remain largely ...unknown. Interleukin-17 (IL-17) ...
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Association between interleukin-17 gene polymorphisms and the risk of laryngeal cancer in a Chinese population.
... 2011). Interleukin 17 (IL-17) was originally cloned from the cDNA sequence of a hybrid rodent T cell in 1993 and named CTLA-8 by Rouvier (Singh et ...
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New insight into the functions of the interleukin 17 receptor adaptor protein Act1 in psoriatic arthritis
... the interleukin-17 (IL-17) receptor, and recent observations have highlighted the signifi cance of IL-17 signaling and localized infl ammation in autoimmune ...
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Gene expression induced by interleukin 17 in fibroblast like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan binding protein TSG 6
... = interleukin-17; MAPK = mitogen-activated protein kinase; RT–PCR = reverse transcriptase– polymerase chain reaction; RA = rheumatoid arthritis; SFC = fibroblast-like synoviocytes; TBST = tris-buffered ...
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Expression of Interleukin-17 associated with disease progression and liver fibrosis with hepatitis B virus infection: IL-17 in HBV infection
... Background/objectives: As a proinflammatory cytokine, interleukin-17 (IL-17) contributes to the inflammation of many autoimmune diseases. We examined IL-17 levels in serum and tissues from ...
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EVALUATING LEVELS OF INTERLEUKIN 1Β AND INTERLEUKIN 17 IN RHUMATOID ARTHRITIS PATIENTS IN THI QAR PROVINCE
... the interleukin 17 (IL-17) cytokine family, including IL-17A (commonly referred to as IL-17), IL-17B, IL-17C, IL-17D, IL-17E (also known as IL-25) and ...
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Butyrate inhibits interleukin-17 and generates Tregs to ameliorate colorectal colitis in rats
... helper 17 (Th17) cells are unique pro- inflammatory Th cells identified by retinoic acid receptor-related orphan receptor gamma t (ROR γ t) and interleukin-17 (IL-17) ...ing ...
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The role of interleukin-17 gene polymorphism (RS612242 C11139G) in the formation of the cryoglobulinemic syndrome in patients with chronic hepatitis C
... of interleukin-17 gene polymorphism (rs612242 C11139G) in the mixed cryoglobulinemia (MC) formation and manifestation of cryoglobulinemic syndrome in patients with chronic hepatitis ...
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Virus Induced Transcriptional Changes in the Brain Include the Differential Expression of Genes Associated with Interferon, Apoptosis, Interleukin 17 Receptor A, and Glutamate Signaling as Well as Flavivirus Specific Upregulation of tRNA Synthetases
... Ingenuity pathway analysis (IPA) was used to identify cellular signaling pathways that are associated with gene expression changes following viral infection. IPA calculates the probability that genes belonging to a ...
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LEVELS OF INTERLEUKIN 17 AND VITAMIN D AND THEIR CORRELATION IN VIRAL HEPATITIS PATIENTS
... The interleukin 17 is usually linked to tissue damage in autoimmune disorders and bacterial and fungal ...of Interleukin-17 and Vitamin D3 (as Calcitriol) in viral hepatitis patients and ...
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Current perspective on the role of the interleukin-23/interleukin-17 axis in inflammation and disease (chronic arthritis and psoriasis)
... Abstract: TH17 is a lymphocyte subset, which is characterized by its polarization to secrete interleukin (IL)-17. IL-23 is the pivotal mediator responsible for TH17 differentiation and the ...
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Interleukin-17-producing decidual CD4+ T cells are not deleterious for human pregnancy when they also produce interleukin-4
... It has been reported that virtually all human memory Th17 cells are contained within the CD161+ fraction of circulating and tissue-infiltrating CD4+ T cells [10, 12]. Interestingly, human Th17 cells express molecules ...
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Clinical associations of serum interleukin 17 in systemic lupus erythematosus
... Although not previously reported, the strong correla- tion found between serum IL-6 and IL-17 levels was in line with expectations, as IL-6 is one of the inflammatory cytokines required, in combination with TGF-b, ...
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Is serum Interleukin 17 associated with early atherosclerosis in obese patients?
... of Interleukin (IL)-17 appears to be the regulation of local tissue inflammation via the coordinated expression of pro-inflammatory cytokines and ...
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Dual role of interleukin 17 in pannus growth and osteoclastogenesis in rheumatoid arthritis
... observed for morphologic changes under an inverted phase-contrast microscope twice a week for 4 weeks. When cultured in DMEM and 10% FCS in the absence or presence of IL-17 (0.1 to 100 ng/ml) or indomethacin (100 ...
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Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor
... We and other investigators have shown that GSK3 represses IL-17A-induced gene expression [33–35]. We previously demonstrated that insulin and IGF1 activate Akt to inhibit GSK3 activities, thus enhancing IL-17A-induced ...
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