interleukin 2 receptor (p55)
An interleukin 2 receptor gamma chain mutation with normal thymus morphology
... the interleukin-2 receptor (IL-2R g ...IL-2 receptor, but also participates in the formation of the IL-4, 7, 9, and 15 re- ceptor ...(T 2 B 1 ...
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Dexamethasone inhibits human interleukin 2 but not interleukin 2 receptor gene expression in vitro at the level of nuclear transcription
... Glucocorticosteroids have an inhibitory effect on the expression of interleukin 2 (IL-2) and interleukin 2 receptor (IL-2R) genes. To determine the mechanisms of this inhibition, ...
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Spontaneous expression of the interleukin 2 receptor gene and presence of functional interleukin 2 receptors on T lymphocytes in the blood of individuals with active pulmonary sarcoidosis
... IL 2 receptor (IL 2R) ...2R p55 protein demonstrated that blood T cells of patients with active sarcoidosis, but not of normal patients, express ...2R p55 protein (2A3), we observed detectable ...
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Partial restoration of impaired interleukin 2 production and Tac antigen (putative interleukin 2 receptor) expression in patients with acquired immune deficiency syndrome by isoprinosine treatment in vitro
... syndrome (AIDS). In 9 of the 10 patients, production of IL-2 from mononuclear cells and Leu 3(+) cells was depressed; expression of Tac antigen on mononuclear cells and Leu 2(+) cells was found to be ...
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Novel Role for Interleukin-2 Receptor-Jak Signaling in Retrovirus Transmission
... Since free HTLV virions are essentially noninfectious and virus transmission can occur through cell-cell contact and fu- sion (21, 30, 46), we addressed the ability of IL-2 and p12 to regulate membrane fusion ...
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T cell subpopulations, expression of interleukin 2 receptor, and production of interleukin 2 and gamma interferon in human American cutaneous leishmaniasis
... Leukocyte subpopulations, the expression of the interleukin-2 IL-2 receptor, and the production of IL-2 and gamma interferon IFN--y were studied in the peripheral blood mononuclear cells[r] ...
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Interleukin 2 and interleukin 2 receptor expression in human corticotrophic adenoma and murine pituitary cell cultures
... stimulated by phorbol myristate acetate. Both adenoma and AtT-20 cells showed detectable amounts of IL-2R mRNA and by immunofluorescence, IL-2R membrane expression. In addition, dual immunofluorescence studies in rat ...
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Interleukin 2 receptor (Tac antigen) expressed on adult T cell leukemia cells
... the interleukin-2 (IL-2) receptor and the proliferative response to exogenous IL-2 of peripheral blood leukemic cells from patients with adult T cell leukemia (ATL) in order to see ...
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Molecular and Structural Characterization of a Novel Escherichia coli Interleukin Receptor Mimic Protein
... the interleukin-2 receptor (IL-2R), interleukin-4 receptor (IL-4R), and interleukin-10 receptor (IL-10R) binding domains, and we showed that purified IrmA can bind to ...
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Altered expression of inflammatory cytokines in primary osteoarthritis by human T lymphotropic virus type I retrovirus infection: a cross sectional study
... soluble interleukin-2 receptor (sIL-2R) and interleukin (IL)-6, and an osteo-destruction marker, deoxypyridinoline, in synovial fluid (SF) samples obtained from 22 HTLV-I carriers and 58 ...
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Linker-scanning mutational analysis of the transcriptional activity of the human immunodeficiency virus type 1 long terminal repeat.
... LTR transcriptional activity obtained by using NXS mutants in Jurkat cells Spl, TATA, LBP-1, UBP-2 a NRE, Negative regulatory element; IL-2, interleukin-2; IL-2Ra, interleukin-2 receptor[r] ...
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Characterization of Immunodeficiency in a Patient With Growth Hormone Insensitivity Secondary to a Novel STAT5b Gene Mutation
... IL, interleukin; GH, growth hormone; JAK, Janus kinase; STAT, signal transducer and activator of transcription; GHR, growth hormone receptor; IL-2R, interleukin 2 receptor; Treg, ...
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Hepatic methotrexate associated lymphoproliferative disorders identified by multiple liver tumors: a case report and review of the literature
... deviation of his digits, although he was adequately treated. Furthermore, no enlargement of superficial lymph nodes was observed. Laboratory studies revealed findings of elevation of C-reactive protein (CRP) and sol- ...
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Allergic diseases in the elderly: biological characteristics and main immunological and non-immunological mechanisms
... cell receptor rearrangement excision circles (TREC)”, have been studied [5], leading to the conclusion that new T cells are produced even in old age, although in very low ...like interleukin (IL)-7, IL-15 ...
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Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier
... We propose that N-SMase is responsible for genera- tions of ceramides with signaling functions. Despite an increase during barrier repair the activity of this enzyme is too low to generate a significant amount of ...
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Lipopolysaccharide stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor
... TNF receptor–deleted mice, we demonstrate that TNF in- duction of c-src is transmitted through the cytokine’s p55, but not p75, ...p55TNF receptor, confirming that LPS-induced osteoclastogenesis is ...
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Role of vasoactive intestinal peptide in osteoarthritis
... VIP is reported to be localized in postganglionic sym- pathetic and sensory nerve fibres that are in close prox- imity to the synovial fluid and serum of arthritis patients. FLS are abundant synovial cell populations ...
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Effect of hypothermia on interleukin-1 receptor antagonist pharmacodynamics in inflammatory-sensitized hypoxic-ischemic encephalopathy of term newborns
... [11–14]. Interleukin-1 receptor antagonist (IL-1Ra) has already demonstrated a protective perinatal efficacy on several organs, especially the brain, exposed to inflammation induced by bacterial compounds ...
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Small Variant STEVOR Antigen Is Uniquely Located within Maurer's Clefts in Plasmodium falciparum-Infected Red Blood Cells
... Pep 2 and Pep 1), while the preimmune serum did not react with pRBCs ...and 2 was compared with that obtained with antibodies to MSP-1 (data not shown), indicating different cellular ...and 2 ...
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Th17 and Th22 cells in psoriatic arthritis and psoriasis
... T-cell receptor (eBioscience), biotin-labelled anti-IL-23R (R&D Systems, Minneapolis, MN, USA) used with Qdot 605 streptavidin conjugate (Invitrogen), PE-labelled anti-CCR6 (BD Biosciences), ...
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