interleukin-2 (T-cell growth factor)
Interleukin 2 receptor (Tac antigen) expressed on adult T cell leukemia cells
... the interleukin-2 (IL-2) receptor and the proliferative response to exogenous IL-2 of peripheral blood leukemic cells from patients with adult T cell leukemia (ATL) in order to ...
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Aberrant Activation of the Interleukin-2 Autocrine Loop through the Nuclear Factor of Activated T Cells by Nonleukemogenic Human T-Cell Leukemia Virus Type 2 but Not by Leukemogenic Type 1 Virus
... of T cells and maintenance of persistent ...human T cells (31, ...human T cells in the presence of interleukin-2 (IL-2) (2, ...in T cells, including the activation ...
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T cell subpopulations, expression of interleukin 2 receptor, and production of interleukin 2 and gamma interferon in human American cutaneous leishmaniasis
... Leukocyte subpopulations, the expression of the interleukin-2 IL-2 receptor, and the production of IL-2 and gamma interferon IFN--y were studied in the peripheral blood mononuclear cells[r] ...
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PDZ domain binding motif of human T cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T cell line
... transcription factor NFAT, constitutively induces the expression of IL-2, and the induced IL-2 promotes the cell growth of HTLV-2-infected T-cell lines, whereas ...
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Human immunodeficiency virus infected adherent cell derived inhibitory factor (p29) inhibits normal T cell proliferation through decreased expression of high affinity interleukin 2 receptors and production of interleukin 2
... induced expression of IL-2 receptor (IL-2R)alpha chain, HLA-class II molecules, and production of IL-2 by these cells; conversely, p29 does not modify the expression of IL-2R beta chain, 4F2, CD9, or ...
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Clonal T cell expansion induced by interleukin 2 therapy in blood and tumors
... of T cell clonal expansion in both tissues and ...of T cell clonotypes was analyzed with a PCR-based method that determines V-D-J junction size patterns in T cell receptor (TCR) ...
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Interferon alpha and interleukin 2 synergistically enhance basic fibroblast growth factor synthesis and induce release, promoting endothelial cell growth
... of cell growth, whereas either cytokine alone had only a slight ...IL- 2 receptor expression was enhanced on IFN-alpha-treated ECs: p55 was increased and p70 was ...in cell culture, ...
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Differential regulation of lymphokine production by distinct subunits of the T cell interleukin 2 receptor
... activated T cells. T cells were activated by stimulation of the antigen receptor complex with anti-CD3 ...unstimulated T cells. IL-2R beta mAb but not IL-2R alpha mAb decreased IL-2-induced ...
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Human T cell leukemia virus type 2 Tax protein induces interleukin 2 independent growth in a T cell line
... EL-4 T-cell line treated with (lane 2) or without (lane 1) 20 µg/ml phorbol myristate acetate and 1 µM ionomycin for 5 hours using RNAiso reagent, according to the manufacturer's instructions ...
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Serum cytokine profiling and enrichment analysis reveal the involvement of immunological and inflammatory pathways in stable patients with chronic obstructive pulmonary disease
... IL-2, interleukin 2; IFN, interferon; GM-CSF, granulocyte-macrophage colony-stimulating factor; CCL2, chemokine ligand 2; SOS1, son of sevenless homologue 1; VEGF, vascular endothelial ...
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Assessment of Pro-Inflammatory Cytokines Level in Stored Blood for Transfusion in Port Harcourt, Nigeria
... as interleukin 1 beta (IL-1β), interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) released by white blood cells ...
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Enhancing anti-melanoma immune responses
... on cell type and state, it is perhaps surprising that few direct comparisons of 1RES function have been made (Martinez-Salas ...in cell lines following transfection with T7 containing bicistronic constmcts ...
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Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias
... dyscrasias. 22 had monoclonal gammopathy of undetermined significance (MGUS), 13 had smoldering myeloma (SMM), 85 had overt multiple myeloma (MM), and 11 had plasma cell leukemia (PCL). Significant serum IL-6 ...
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fimmu-10-01966.pdf
... activated T cells undergo apoptotic death and the effector T cell pool contracts (41, ...Memory T cells are responsible for mediating ongoing immune ...proliferating T cells [reviewed ...
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Urine-derived stem cells for potential use in bladder repair
... Stem cell-based therapy for bladder repair is most relevant to congenital bladder conditions (for example, bladder exstrophy) or conditions such as radiation damage, infec- tion, interstitial cystitis, neuropathic ...
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<p>CCDC7 Activates Interleukin-6 and Vascular Endothelial Growth Factor to Promote Proliferation via the JAK-STAT3 Pathway in Cervical Cancer Cells</p>
... The recombinant human proteins VEGF and IL-6 were purchased from Pepro Tech (Suzhou, China). Anti-STAT3 (1:1000), anti-JAK (1:1000), anti-phospho-STAT3 (Y705) (1:1000), and anti-phospho-JAK (Y1007/1008) (1:1000) ...
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Epidermal Growth Factor Receptor Expression Licenses Type 2 Helper T Cells to Function in a T Cell Receptor Independent Fashion
... Moleculare Cell biology, Jena) by using lipofectamin (Invitrogen) according to the manufacturer ...MgCl2; 2 mM orthovanadate; 1 mM dithiothreitol; 20 mg/ml aprotinin; 20 mg/ml leupeptin supplemented with ...
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Immune reactivity in the nervous system: modulation of T lymphocyte activation by glial cells
... Astrocytes present myelin basic protein to encephalitogenic T cell lines.. prostaglandin E and an interleukin-1 like-factor by astrocytes and C6 glioma cells.[r] ...
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Macrophage-mediated response to hypoxia in disease
... phenotype, with the expression of VEGF and other proangiogenic factors to revascularize the wound site. How- ever, there are still a limited number of publications that have examined the presence of macrophages in ...
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Skin Targeting Approaches in Cosmetics
... for skin targeting. In a study by Ryu et al. in 2014, the potential of elastin like polypeptide was explored and discussed for skin targeting. A promising method for targeting these anticancer drugs to tumors, ...
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