Intermediate filament
GFAP isoforms control intermediate filament network dynamics, cell morphology, and focal adhesions
... Abstract Glial fibrillary acidic protein (GFAP) is the characteristic intermediate filament (IF) protein in astro- cytes. Expression of its main isoforms, GFAPa and GFAPd, varies in astrocytes and ...
20
Molecular interactions of the mammalian intermediate filament protein synemin with cytoskeletal proteins present in adhesion sites
... 2006). Intermediate filament proteins are linked to hemidesmosomes via interactions with the C-terminal plakin repeats of plectin and BP230, which interacts with integrin β4 (Koster et ...
132
Vimentin intermediate filament assembly regulates fibroblast invasion in fibrogenic lung injury
... Vimentin is a dynamic type III intermediate filament, cytoskeletal protein (31). Structurally, vimentin is a coiled-coil protein composed of central α-helical regions linked by connecting segments and ...
18
Expression of Intermediate Filament Nestin in Blood Vessels of Neural and Non-neural Tissues
... Our previous findings performed in rat tissues demon- strated that nestin is expressed in endothelial cells of newly formed blood vessels of developing intra- and extraembryo- nic tissues (14). In the adult rat tissues, ...
7
The intestinal intermediate filament network responds to and protects against microbial insults and toxins
... of intermediate filaments in the apical cytoplasm of intestinal cells is evolutionarily conserved, forming a sheath that is anchored to apical junctions and positioned below the microvillar brush border, which ...
13
What can be learned from intermediate filament gene regulation in the mouse embryo
... Int J De\' BioI 39 1 43 457 (1995) Review What can be learned from intermediate filament gene regulation in the mouse embryo' PHILIPPE DUPREY' and DENISE PAULIN Laboratoire de Biologie Moleculaire de[.] ...
15
Isomin: a novel cytoplasmic intermediate filament protein from an arthropod species
... the Intermediate Filament protein C (IFC) subfamily of Caenorhabditis elegans IF proteins, which are molecular constituents of the nematode intestinal terminal ...
14
Complete structure of an epithelial Keratin Dimer : implications for intermediate filament assembly
... Keratins are cytoskeletal proteins that hierarchically arrange into filaments, starting with the dimer sub-unit. They are integral to the structural support of cells, in skin, hair and nails. In skin, keratin is thought ...
23
Paraneoplastic neuronal intermediate filament autoimmunity
... Antigen specificity was supported by the patient whose Merkel cell carcinoma had a NIF staining profile matching her NIF-IgG serologic profile. Affected patients, when treated with immunotherapy, generally improved, while ...
14
Expression of the intermediate filament nestin during rodent tooth development
... Int J Dn BioI 39 947 956 (1995) 947 Original Article Expression of the intermediate filament nestin during rodent tooth development CATHARINA TERLlNG' 2, ALON RASS,,3, THIMIOS A MITSIADIS', KAJ FRIED'[.] ...
10
Biological adhesion of the flatworm Macrostomum lignano relies on a duo-gland system and is mediated by a cell type-specific intermediate filament protein
... a staining of cells located around the mouth by macif1 in situ hybridization (Figures 5A and 7A). This weak expres- sion in the mouth is most likely due to a cross reaction with another intermediate ...
15
Transitin, a nestin like intermediate filament protein, mediates cortical localization and the lateral transport of Numb in mitotic avian neuroepithelial cells
... cytoplasmic intermediate filaments (Rubin et ...same intermediate filament subclass due to the sequence homology in their rod domain, and because they are expressed in NE cells and muscle precursors ...
9
The vimentin intermediate filament network restrains regulatory T cell suppression of graft versus host disease
... optimally treat inflammatory diseases in patients. Understanding the cellular processes that control Treg function may allow for the augmentation of therapeutic efficacy. In contrast to activated conventional T cells, in ...
19
Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle
... using phospho-Ser/Thr column chromatography enrichment. Our data showed that MTM1 depletion directly affected fila- ment assembly without modifying the phosphorylation level of desmin (Supplemental Figure 6B), as ...
17
Understanding the plasma and magnetic field evolution of a filament using observations and non linear force free field modelling : evolution of an intermediate filament
... the filament when it is seen at the west limb from the STEREO-B ...the filament is near Sun-centre from the AIA ...the filament plasma are studied during its disk passage using the Atmospheric ...
17
Giant axonal neuropathy–associated gigaxonin mutations impair intermediate filament protein degradation
... ing FLAG-tagged full-length vimentin (FLAG-FL-VIM), FLAG- ΔN-VIM, FLAG-ΔC-VIM, and FLAG-Rod-VIM. As expected, FLAG- ΔC-VIM formed filaments (35, 36), whereas FLAG-ΔN-VIM and FLAG-Rod-VIM appeared particulate ...
13
A neuronal death model: overexpression of neuronal intermediate filament protein peripherin in PC12 cells
... These results show that caspase-3 activation in pEGFP- Peripherin cells was blocked by a calpain inhibitor, which also suppressed neuronal cell death in well-differ- entiated pEGFP-Perip[r] ...
13
Human upper epidermal cytoplasmic antibodies are directed against keratin intermediate filament proteins
... increased incidence of U-Cyt antibodies has also been reported in the sera of patients with noncutaneous diseases, such as pulmonary neoplasms. They have been found in addition in the sera of some normal individuals. In ...
9
Gigaxonin glycosylation regulates intermediate filament turnover and may impact giant axonal neuropathy etiology or treatment
... Given that S272 and T277 may also be the primary sites of inducible gigaxonin O-GlcNAcylation (Supplemental Figure 1), the dynamic, site-specific glycosylation of S272 and T277 may be [r] ...
22
Functions of the intermediate filament cytoskeleton in the eye lens
... Intermediate filaments (IFs) are a key component of the cytoskeleton in virtually all vertebrate cells, including those of the lens of the eye. IFs help integrate individual cells into their respective tissues. ...
13