Intermediate Filament Protein
Biological adhesion of the flatworm Macrostomum lignano relies on a duo-gland system and is mediated by a cell type-specific intermediate filament protein
... invertebrate intermediate filament protein including a head-, a rod- and a tail domain (Figure ...predicted protein shared the long version of the 1B subdo- main with six additional heptamers ...
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Transitin, a nestin like intermediate filament protein, mediates cortical localization and the lateral transport of Numb in mitotic avian neuroepithelial cells
... the intermediate filament ...of intermediate filaments in the M phase is important for cytokinesis (Ando et ...rigid intermediate filament structure of vimentin- transitin by ...
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Molecular interactions of the mammalian intermediate filament protein synemin with cytoskeletal proteins present in adhesion sites
... amino acids and hence serves as a very good surface for binding of the phospholipids, such as phosphatidylinositol-4, 5-bisphosphate (PIP2) (Rees et al., 1990). The talin head domain also contains a ...
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Giant axonal neuropathy–associated gigaxonin mutations impair intermediate filament protein degradation
... ing FLAG-tagged full-length vimentin (FLAG-FL-VIM), FLAG- ΔN-VIM, FLAG-ΔC-VIM, and FLAG-Rod-VIM. As expected, FLAG- ΔC-VIM formed filaments (35, 36), whereas FLAG-ΔN-VIM and FLAG-Rod-VIM appeared particulate ...
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A neuronal death model: overexpression of neuronal intermediate filament protein peripherin in PC12 cells
... Transgenic mice overexpressing wild-type mouse NF- H or NF-M show neither muscle atrophy nor motor neuron loss, despite prominent axonal swelling and peri- karyal neurofilament accumulation in motor neurons [66,67]. ...
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Isomin: a novel cytoplasmic intermediate filament protein from an arthropod species
... other intermediate filaments (IFs) reveals that isomin shares the IF tripartite molecular ...IF protein from the mollusc Helix aspersa (IFEA, [Swiss-Prot:P22488]); the IF protein from the annelid ...
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Tragedy in a heartbeat: malfunctioning desmin causes skeletal and cardiac muscle disease
... Muscle fiber deterioration resulting in progressive skeletal muscle weakness, heart failure, and respiratory distress occurs in more than 20 inherited myopathies. As discussed in this Review, one of the newly identified ...
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Nebulin, a multi functional giant
... thin filament length (note that it is not known whether tropomodulin and leiomodin can bind to the same thin ...thin filament; its N-terminal region extends near the pointed end of the thin filament, ...
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Expression of Intermediate Filament Nestin in Blood Vessels of Neural and Non-neural Tissues
... Intermediate filament protein nestin was originally iso- lated from the embryonic nervous tissue (9) and consi- dered as a marker of neural stem cells (7, ...
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Sarcomere number regulation maintained after immobilization in desmin null mouse skeletal muscle
... muscle-specific intermediate filament protein, is one of the earliest known myogenic markers expressed in both cardiac and skeletal muscles (Choi et ...DNA-binding protein requiring the basic ...
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Proteome analysis of human Wharton's jelly cells during in vitro expansion
... ubiquituos intermediate filament protein and the first protein to be expressed during cell differentiation is com- mon to other MSCs such as bone marrow and cord blood derived ...
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Pathogenesis of FUS-associated ALS and FTD: insights from rodent models
... Originally, FUS was identified for its role as a fu- sion oncoprotein in the development of round cell liposcarcomas and human myeloid leukaemias. Nine years before the recognition of its relevance to ALS/ FTD, two ...
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Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle
... chaperone protein, αB-crystallin (OMIM 608810), are associated with cardiomyopathy and myopathy, both belonging to the desmin-related myopathy (DRM) and the des- min-related cardiomyopathy (DRCM) subgroups of IF ...
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The central nervous system of Oweniidae (Annelida) and its implications for the structure of the ancestral annelid brain
... the intermediate filaments which run through the neuropil of the cns of both species inves- ...a protein called SCO-spondin which contributes to the formation of Reissner’s fibre ...of intermediate ...
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Adenosinergic and cholinergic control mechanisms during hypoxia in the epaulette shark (Hemiscyllium ocellatum), with emphasis on branchial circulation
... Hypoxia initiated blood flow in two longitudinal blood vessels in the filament of the epaulette shark. In normoxia, we could observe small vascular openings between each lamella, but no apparent vessel leading ...
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Advances with RNA interference in Alzheimer’s disease research
... Compared with other therapeutics, the principal advantage of RNAi is that all targets – including those that are usually unable to be targeted with drugs – are able to be drugged using RNAi. This is because, in theory, ...
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Chorea as a clinical feature of the basophilic inclusion body disease subtype of fused-in-sarcoma-associated frontotemporal lobar degeneration
... dentatorubral-pallidoluysian atrophy. No mutation was found in the genes for tau, TDP-43, FUS, granulin, amyl- oid precursor protein, presenilin-1, or presenilin-2. Based on clinical findings, she was diagnosed ...
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Determination and Validation of Markers for Heat Induced Damage in Wool Proteins
... cause protein deterioration, impacting negatively on the value or condition of these ...II intermediate filament proteins (keratins) extracted from wool was characterised using advanced quantitative ...
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Trichinella britovi muscle larvae and adult worms: stage specific and common antigens detected by two dimensional gel electrophoresis based immunoblotting
... It is important to note that in accordance with previ- ous studies [11, 60, 61], the 10 dpi sera in the present study identified the protein enolase in crude ML ex- tract. Bernal et al. [61] revealed that enolase ...
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The vimentin intermediate filament network restrains regulatory T cell suppression of graft versus host disease
... which protein kinase C-θ (PKC-θ) localizes to the contact point between T cells and antigen-presenting cells, in human and mouse Tregs, PKC-θ localizes to the opposite end of the cell in the distal pole complex ...
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