intestinal epithelial barrier
Heparan sulfate and syndecan 1 are essential in maintaining murine and human intestinal epithelial barrier function
... maintain intestinal epithelial barrier function and develop an excessive and potentially fatal efflux of plasma ...of intestinal epithelial cells during PLE ...predominant ...
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Identification of multi-drug resistant Pseudomonas aeruginosa clinical isolates that are highly disruptive to the intestinal epithelial barrier
... the intestinal tract alone can be a major source of systemic sepsis and death among immuno-com- promised patients ...the intestinal tract to be the single most important reservoir for this pathogen in cases ...
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Intestinal epithelial barrier: The target for pathogenic Escherichia coli
... other intestinal pathogens, ...the epithelial barrier and efficiently colonize the intestinal epithe- ...The barrier function of the intestinal epithelium is achieved by the ...
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Structural alterations of the intestinal epithelial barrier in Parkinson’s disease
... the intestinal epithelial barrier (IEB) have been consistently reported in digestive disorders such as irritable bowel syndrome and inflammatory bowel ...
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Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity
... protecting intestinal epithelial barrier function against disruption induced by TNF-α/IFN-γ by suppressing activation of the MLCK-pMLC signalling ...
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Role of myosin light chain kinase in intestinal epithelial barrier defects in a rat model of bowel obstruction
... Lastly, treatment with ML-7 did not significantly decrease the bacterial CFU numbers in the spleen and liver, suggesting that bacterial passage through the obstructed gut may not involve MLCK-dependent para- cellular ...
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Ungewiß, Hanna (2019): Adhesive and signaling properties of Dsg2 in intestinal epithelial barrier regulation. Dissertation, LMU München: Fakultät für Biologie
... columnar epithelial cells that are tightly connected by a set of intercellular junctional complexes (Capaldo et ...the intestinal epithelium is organized in a three-dimensional structure consisting of ...
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Intestinal Epithelial Barrier Disruption through Altered Mucosal MicroRNA Expression in Human Immunodeficiency Virus and Simian Immunodeficiency Virus Infections
... Widespread depletion of miRNA has been reported in PBMCs of HIV-infected patients and infected cell lines (53, 55). These studies found that miRNA depletion was likely due to the inflam- FIG 5 Chronic SIV infection ...
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Staphylococcal enterotoxin B suppresses Alix and compromises intestinal epithelial barrier functions
... the epithelial barrier dysfunction, a large quantity of macromolecular antigens can be transported into the deep region of the intestinal ...an intestinal allergy may be induced ...induces ...
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Intestinal CRF Receptor Subtypes Mediate Divergent Roles in Stress-Induced Intestinal Epithelial Barrier Dysfunction.
... stress-induced intestinal barrier dysfunction in pigs during multiple phases of life and production, providing enhanced production value and animal ...preventing intestinal dysfunction resulting from ...
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Blood–brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders
... increased epithelial tightness and decreased permeability to macromolecules [86], appears signifi- cantly elevated in the ASD cortex, suggesting either a more competent BBB or a compensatory mechanism for ...
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Intestinal T lymphocyte homing is associated with gastric emptying and epithelial barrier function in critically ill: a prospective observational study
... The intestinal epithelial barrier was assessed, quantifying serum concentrations of intestinal fatty acid binding protein (I-FABP), ileal bile-acid binding protein (I-BABP) and zonulin-1 by ...
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Severe burn injury alters intestinal microbiota composition and impairs intestinal barrier in mice
... destroy intestinal epithelial barrier, resulting in the leakage of bacteria and bacterial metabolites from the intestinal lumen into the mucosa or circulatory system [5, 6, ...causes ...
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Intestinal barrier dysfunction in severe burn injury
... protect intestinal epithelial barrier function, and the potential mechanism may be related to the IL-6-induced upregulation of keratin-8 and 18 in intestinal epithelial cells ...restore ...
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Effects of polymorphonuclear leukocyte transmigration on the barrier function of cultured intestinal epithelial monolayers
... the intestinal epithelial ...human intestinal epithelial cell line (T84 cells) by chemotactic gradients produced by formyl methionyl leucyl phenylalanine ...
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"Targeted disruption of the epithelial-barrier by Helicobacter pylori"
... protective barrier between harmful luminal contents and the underlying tis- sue ...gastric epithelial barrier by altering the structure and function of the apical junc- tional ...gastric ...
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Campylobacter jejuni enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrA
... The most important result of the currently pre- sented work is that HtrA of C. jejuni can cleave occlu- din in vitro, during infection of cultured polarised Caco-2 cells and in biopsies of campylobacteriosis cases in ...
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Ammonia inhibits cAMP regulated intestinal Cl transport Asymmetric effects of apical and basolateral exposure and implications for epithelial barrier function
... indicated that physiologically-relevant concentrations of ammonia (as NH4Cl) markedly inhibit cyclic nucleotide-regulated Cl- secretion but not the response to the Ca2+ agonist carbachol. Inhibition by ammonia was ...
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Influence of the Multispecies Probiotic Ecologic® BARRIER on Parameters of Intestinal Barrier Function
... A large part of the immune system (approximately 80%) is concentrated in and around the intestinal mucosa. The intestinal microbiota is involved in maturation of the immune system as demonstrated in studies ...
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A RATIONALIZED DESCRIPTION ON STUsDY OF INTESTINAL BARRIER, DRUG PERMEABILITY AND INTESTINAL PERMEATION ENHANCERS
... In many respects the Caco-2 cells are therefore functionally similar to the human small intestinal enterocyte, despite the fact that they originate from a human colorectal carcinoma. The methods that are based on ...
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