Intestinal perfusion
PACLITAXEL DISPOSITION STUDIES USING P GP INHIBTOR & INDUCER BY SINGLE PASS INTESTINAL PERFUSION IN RATS
... Jejunal segment was used for performing Single Pass Intestinal Perfusion. The rationale for the selection of jejenum is due to the overexpression of P-glycoprotein when compared with other segments. Drug ...
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Determination of site of absorption of propranolol in rat gut using In situ single-pass intestinal perfusion
... of intestinal absorption of propranolol have been reported using the Ussing ...Single-Pass Intestinal Perfusion to study permeability and site of intestinal absorption of propranolol was ...
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Mechanisms of microemulsion enhancing the oral bioavailability of puerarin: comparison between oil-in-water and water-in-oil microemulsions using the single-pass intestinal perfusion method and a chylomicron flow blocking approach
... MEs may be the stomach. In addition, the absorption of the W/O-ME was much better than that of the O/W-ME in all the intestinal segments. Additionally, with the chylomicron flow blocking model, the present study ...
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Effect of Dietary Calcium and Age on Jejunal Calcium Absorption in Humans Studied by Intestinal Perfusion
... When a test solution containing no calcium was infused into the jejunal lumen of 15 normal subjects, the rate of calcium secretion was 0.025±0.002 mmol/60 cm per h, and the average calci[r] ...
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Absorption of Cholesterol from a Micellar Solution: Intestinal Perfusion Studies in Man
... Each of the components of the micelle was absorbed to a different extent during passage through the test segment of jejunum. Bile salt was not absorbed (mean, -3%), but micellar monoglyceride was rapidly hydrolyzed and ...
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Mechanism of acid induced release of secretin in rats Presence of a secretin releasing peptide
... Results Pancreatic secretion andplasma concentrations ofsecretin and CCK in response to intestinal perfusion in donor rats: Upper intestinal perfusion of 0.01 N HCl resulted in a signifi[r] ...
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Clot Dissolution: A Novel Treatment of Midgut Volvulus
... We strongly recommend this combined treatment in patients with critical in- testinal ischemia after derotation of a midgut volvulus. This novel form of treatment is simple and should be performed in the acute setting. In ...
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Enhancement of absorption and bioavailability of echinacoside by verapamil or clove oil
... Methods: ECH absorption behaviors were investigated by everted gut sac model in vitro and single-pass intestinal perfusion model in situ. Pharmacokinetics study was performed to investigate the influences ...
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Intestinal angina in a patient with hypertrophic obstructive cardiomyopathy: a case report
... widest intestinal perfusion area, was patent in this patient; how- ever, in many previous reports concerning intestinal an- gina, stenosis of this artery was demonstrated, and angioplasty was ...
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Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation, necrosis, apoptosis in intestinal epithelial cells and electrolyte and water transport and epithelial barrier function in mice
... to intestinal perfusion to evaluate net fluid and electrolyte ...the perfusion, the animals were sacrificed, and the dry weight (after desiccation at 90°C for 72 h) of the intestinal segment ...
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<p>Improving The Oral Absorption Of Nintedanib By A Self-Microemulsion Drug Delivery System: Preparation And In Vitro/In Vivo Evaluation</p>
... In the present study, a self-microemulsion drug delivery system composed of MCT (oil phase), Cremophor RH 40 (surfactant) and ethylene glycol (co-surfactant) for the oral administration of nintedanib was developed. The ...
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“Simultaneous HPLC-UV Method for Quantification of Atorvastatin in Rat Plasma and Intestinal Perfusate for Pharmacokinetic Studies” by Muznah AlKhani, Antoun Al-Laham, Mohammed Amer Al-Mardini, Syria.
... Blood samples were collected from rats by cardiac puncture, sonicated for 5 minutes to lyse RBCs, centrifuged at 3500 rpm for 10 minutes, and the plasma supernatant was carefully separated and collected in polypropylene ...
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“Rapid HPLC-UV Method for Quantification of Valsartan in Plasma and Intestinal Perfusate for Pharmacokinetic Studies” by Muznah AlKhani, Antoun Al-Laham, Mohammed Amer Al-Mardini, Syria.
... 16.7 mM glucose and 0.01 mM sodium taurocholate, adjusted to pH7.4 using NaOH). Rats were obtained from experimental animals facility, Faculty of Pharmacy, Damascus University. An intramuscular injection of Ketamine 60 ...
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Sources of Variability in the Use of Standardized Perfusion Value for HCC Studies
... CT perfusion exams, there is lack of standardization because of different acquisition image protocols and different software analysis applied to obtain perfusion ...CT perfusion exams, ...processes ...
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Differentiating Atypical Hemangiomas and Metastatic Vertebral Lesions: The Role of T1 Weighted Dynamic Contrast Enhanced MRI
... Our study takes advantage of spine DCE MR imaging perfu- sion as a noninvasive method of obtaining quantitative parame- ters representing the physiology of the microvascular environ- ment of each lesion. Except for the ...
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Effects of Yacon on Colonic IFN-γ and Goblet Cells of 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis Mouse Model
... The induction of colitis in GII, GIII, GIV, and GV mice was performed by intrarectal application of TNBS (Sigma-Aldrich®, USA), based on the method described by Steinhoff and Visekruna [4] . To make intrarectal solution, ...
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Computed Tomography Perfusion Imaging on Traumatic Cerebral Contusion: A Preliminary Report
... CTP has been introduced as a simple imaging technique that can be used in routine clinical practice. It has gained recognition in management cases of acute stroke and other cerebrovascular disorders because it is able to ...
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The myocardial perfusion scintigraphy in asymptomatic diabetic patients
... Prevalence and prognostic value of perfusion defects detected by stress technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography in asy[r] ...
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Function of Vascular Smooth Muscle and Its Sympathetic Innervation in the Newborn Dog
... The effects of sympathetic nerve stimulation and vasoconstrictors on perfusion pressure in the hindquarters of newborn, young, and adult dogs* Change in perfusion pressure at various age[r] ...
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The utility of cardiac stress testing for detection of cardiovascular disease in breast cancer survivors: a systematic review
... myocardial perfusion imaging appears to be beneficial for long-term follow-up to radiotherapy, and stress echocardiography appears to be beneficial in detecting left ventricular dysfunction following anthracycline ...
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