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Intrahepatic Cholestasis

Perinatal outcomes in intrahepatic cholestasis of pregnancy with monochorionic diamniotic twin pregnancy

Perinatal outcomes in intrahepatic cholestasis of pregnancy with monochorionic diamniotic twin pregnancy

... ICP: Intrahepatic cholestasis of pregnancy; MCDA: Monochorionic diamniotic; MCMA: Monochorionic monoamniotic; NICU: Neonatal intensive care unit; PPROM: Preterm premature rupture of membrane; TBA: Total ...

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Bile Acid Effects on Placental Damage in Intrahepatic Cholestasis of Pregnancy

Bile Acid Effects on Placental Damage in Intrahepatic Cholestasis of Pregnancy

... Intrahepatic cholestasis of pregnancy (ICP) is a disorder of pregnancy occurring in the third trimester, characterized by pruritus, accompanied by the elevation of serum transaminases and serum bile acids ...

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Progressive familial intrahepatic cholestasis: diagnosis, management, and treatment

Progressive familial intrahepatic cholestasis: diagnosis, management, and treatment

... recurrent intrahepatic cholestasis (BRIC-1, also known as Summerskill syndrome) is a milder form of PFIC-1 which is also related with FIC1 gene mutation, where recur- rent episodes of cholestasis ...

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Perinatal outcomes and intrahepatic cholestasis of pregnancy: a prospective study

Perinatal outcomes and intrahepatic cholestasis of pregnancy: a prospective study

... of intrahepatic cholestasis of pregnancy. Development of intrahepatic cholestasis of pregnancy was highly significantly associated with small for gestational age (SGA, p-value: ...

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Progressive familial intrahepatic cholestasis

Progressive familial intrahepatic cholestasis

... The first type, called PFIC1 (Byler disease) is caused by mutations in the ATP8B1 gene (also designated FIC1) [6,12]. This gene, which encodes a P-type ATPase, is located on human chromosome 18 and is also mutated in the ...

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Original Article Application of high-throughput sequencing technologies with target capture/target next-generation sequencing in diagnosis of neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD)

Original Article Application of high-throughput sequencing technologies with target capture/target next-generation sequencing in diagnosis of neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD)

... were homozygous mutation (c.852_855del), and other 5 were compound heterozygous mutation and had mutation site c.852_855del as well. c.852_855del mutation is a high fre- quency mutation site in Chinese population and ...

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Progressive Familial Intrahepatic Cholestasis: A Rare Cause of Cirrhosis in Young Adult Patients

Progressive Familial Intrahepatic Cholestasis: A Rare Cause of Cirrhosis in Young Adult Patients

... Hepatic cirrhosis is an important cause of morbidity and mortality. An unusual case of cirrhosis and portal hypertension in an 18-year-old patient secondary to Progressive Intrahepatic Cholestasis is ...

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Mother’s intrahepatic cholestasis does not affect her daughter’s health

Mother’s intrahepatic cholestasis does not affect her daughter’s health

... Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder which usually manifests in the third trimester of gestation as skin itching especially on the palms and soles and as increased serum bile ...

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Pancreatic adenocarcinoma in type 2 progressive familial intrahepatic cholestasis

Pancreatic adenocarcinoma in type 2 progressive familial intrahepatic cholestasis

... Familial Intrahepatic Cholestasis (PFIC-2), also known as BSEP disease, is one of the genetically determined cholestatic diseases and results from mutations in ABCB11, which encodes the bile salt export ...

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Intrahepatic cholestasis in subclinical and overt hyperthyroidism: two case reports

Intrahepatic cholestasis in subclinical and overt hyperthyroidism: two case reports

... The patient had no history of chronic disease, smoking, pharmaceutical or herbal medications, infections, abuse of alcohol, blood transfusion or traveling. On initial examination, there was significant jaundice, the skin ...

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Bile acids: Method validation and diagnosis of intrahepatic cholestasis of pregnancy

Bile acids: Method validation and diagnosis of intrahepatic cholestasis of pregnancy

... A BSTRACT : The intrahepatic cholestasis is the most common of hepatopathies specific to pregnancy. Serum total bile acids concentration (ACIBI) is the most sensitive and specific diagnostic marker of this ...

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Original Article Expression of vascular endothelial growth factor (VEGF) under hypoxia in placenta with intrahepatic cholestasis of pregnancy and its clinically pathological significance

Original Article Expression of vascular endothelial growth factor (VEGF) under hypoxia in placenta with intrahepatic cholestasis of pregnancy and its clinically pathological significance

... Intrahepatic cholestasis of pregnancy (ICP) is an obstetric complication occurs in late preg- nancy with the clinical features of pruritus and increase of serum bile acid and CG in late preg- ...

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Original Article Treatment of intrahepatic cholestasis of pregnancy using ursodeoxycholic acid: a meta-analysis

Original Article Treatment of intrahepatic cholestasis of pregnancy using ursodeoxycholic acid: a meta-analysis

... Abstract: Intrahepatic cholestasis of pregnancy (ICP) is one pregnant-associated complication that is manifested as skin itches, liver dysfunction and elevated bile ...

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Intrahepatic Cholestasis Associated with Parenteral Nutrition in Premature Infants

Intrahepatic Cholestasis Associated with Parenteral Nutrition in Premature Infants

... Intrahepatic cholestasis (direct bilirubin 1.5 mg/dl) associated with PN developed in 14 or 239@ of these infants. The mean time on PN to onset of cholestasis was 42 days, and the choles[r] ...

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Pregnancy outcome in women with intrahepatic cholestasis of pregnancy

Pregnancy outcome in women with intrahepatic cholestasis of pregnancy

... years, intrahepatic cholestasis of pregnancy (ICP) has also been described as jaundice in pregnancy, recurrent jaundice of pregnancy, idiopathic jaundice of pregnancy, obstetric hepatosis, hepatosis ...

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Health behavior after intrahepatic cholestasis of pregnancy

Health behavior after intrahepatic cholestasis of pregnancy

... Background: Pregnancy is an opportunity to adopt favorable health behaviors. We studied whether intrahepatic cholestasis of pregnancy (ICP) promotes favorable health behavior in later life. Design: A ...

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Intrahepatic cholestasis of pregnancy

Intrahepatic cholestasis of pregnancy

... Intrahepatic cholestasis of pregnancy (ICP) is a cholestatic disorder characterized by (i) pruritus with onset in the second or third trimester of pregnancy, (ii) elevated serum aminotransferases and bile ...

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Fetal and neonatal outcomes in intrahepatic cholestasis of pregnancy

Fetal and neonatal outcomes in intrahepatic cholestasis of pregnancy

... Intrahepatic cholestasis of pregnancy is a reversible cholestasis of pregnancy, occurring in late second and third trimester, which complicates maternal as well as fetal outcome, with overall ...

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Intrahepatic Cholestasis of Pregnancy in Women With Twin Pregnancy

Intrahepatic Cholestasis of Pregnancy in Women With Twin Pregnancy

... The aim of the present work was to determine maternal and fetal outcomes of intrahepatic cholestasis of pregnancy (ICP) in twin pregnancies. All twin pregnancies delivered above 28 gestational weeks in West ...

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Effect of Maternal Intrahepatic Cholestasis on Fetal Steroid Metabolism

Effect of Maternal Intrahepatic Cholestasis on Fetal Steroid Metabolism

... Estriol, estriol sulfate, progesterone, and 17 neutral steroid sulfates, including estriol precursors and progesterone metabolites, were determined in 27 cord plasma samples collected after pregnancies complicated by ...

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