Invasion and angiogenesis
SDF 1/CXCR7 axis regulates the proliferation, invasion, adhesion, and angiogenesis of gastric cancer cells
... cancer invasion and tumor ...through angiogenesis and VEGF ...adhesion, invasion, angiogenesis, VEGF production, and tumor ...sion, invasion, and angiogenesis, the role of SDF-1/ ...
10
ISL1 is upregulated in breast cancer and promotes cell proliferation, invasion, and angiogenesis
... Here, our study indicates that ISL1 is upregulated in breast cancer cell lines and tissue samples. Moreover, a high expression of ISL1 is corrected with tumor size, metastasis, and poor prognosis. Several functional ...
9
lncRNA TUG1 modulates proliferation, apoptosis, invasion, and angiogenesis via targeting miR-29b in trophoblast cells
... MicroRNAs (miRNAs) are a class of small non-coding RNAs with 22 nucleotides, which are derived from hair- pin precursors and post-transcriptionally regulate gene expression via transcript degradation or translation ...
12
Tumor treating fields inhibit glioblastoma cell migration, invasion and angiogenesis
... and invasion, angiogenesis is another essential factor in cancer progression [24, ...that angiogenesis and invasion rely on similar biological mechanisms ...[38]. Angiogenesis can be ...
12
HCRP-1 regulates cell migration, invasion and angiogenesis via Src/ FAK signaling in human prostate cancer
... migration, invasion and angiogenesis, PC3 and LnCap cells were transfected with siRNA for HCRP-1, phosphorylation of Src and FAK was ...adhesion, angiogenesis and migration [18, ...migration, ...
11
Parallels in invasion and angiogenesis provide pivotal points for therapeutic intervention
... proliferation, invasion) and indirect (anti-angiogenic) effectsand these have been well described in many systems (Mendelsohn ...and angiogenesis (Tortora ...
16
Long non-coding RNA LINC01314 represses cell migration, invasion, and angiogenesis in gastric cancer via the Wnt/β-catenin signaling pathway by down-regulating KLK4
... inhibit angiogenesis in GC cells by negatively regulating the Wnt/β-catenin signaling ...and invasion in OSCC due to inactivation of the PI3K/AKT signaling pathway ...lympho-vascular invasion of ...
14
MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11
... and invasion are essential processes for solid tumor growth and ...cancer angiogenesis, invasion and other signaling pathways important for tumor development are still unclear in the context of tumor ...
16
Indirubin inhibits cell proliferation, migration, invasion and angiogenesis in tumor-derived endothelial cells
... migration, invasion and angiogenesis of ...Td-EC angiogenesis such as tumor hypoxia, epithelial–mesenchymal transition, cancer stem-like cells, and some transcription ...
8
Long non-coding RNA PAXIP1-AS1 facilitates cell invasion and angiogenesis of glioma by recruiting transcription factor ETS1 to upregulate KIF14 expression
... result in a simulated process of secretion of autoanti- bodies, with the progression of autoimmune diseases [32]. It has been well established that ETS1, as a proto- oncoprotein, promotes invasive behaviors in ...
12
Inhibiting GIT1 reduces the growth, invasion, and angiogenesis of osteosarcoma
... In the present study, we first revealed that GIT1 was distrib- uted in more than half of human osteosarcoma tissues, sug- gesting it may play an important role in osteosarcoma growth or metastasis. Then, experiments in ...
11
3d Biomimetic Model for Cellular Invasion in Angiogenesis and Cancer
... to angiogenesis, the morphogenetic process of endothelial invasion and sprout extension has been difficult to observe in vivo and models of sprouting in vitro have largely ignored the key initial conditions ...
133
RERG suppresses cell proliferation, migration and angiogenesis through ERK/NF-κB signaling pathway in nasopharyngeal carcinoma
... The tumor microenvironment, composed of non- cancer cells and their stroma, influences on metastasis as a dynamic process [42] and angiogenesis response to a tumor [43]. Various of pro-tumorigenic factors, includ- ...
15
Differential proteomics analysis of low- and high-grade of astrocytoma using iTRAQ quantification
... Abstract: Astrocytoma is one of the most common types of brain tumor, which is histologically and clinically classified into four grades (I–IV): I (pilocytic astrocytoma), II (diffuse astrocytoma), III (anaplastic ...
13
DELTA-TOCOTRIENOL IS THE MOST BIOACTIVE ANTICANCER AGENT AGAINST GASTRIC CANCER
... proliferation, angiogenesis, invasion, and extravasation into liver and ...as invasion of gastric cancer cells, likely limiting the process of metastasis in ...to invasion, intravasation, ...
8
Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications
... and invasion assay demonstrate that Gem-CM-induced effect on HUVEC migration (Figure 6A) and invasion (Figure 6B) was significantly inhibited upon neutralization of IL-8 in ...
11
Original Article CCL4 promotes the cell proliferation, invasion and migration of endometrial carcinoma by targeting the VEGF-A signal pathway
... tion of CCL4, CCR5 and VEGF-A is associated with the clinical grade of the tumors in EC using an immunohistochemistry assay. We further confirmed the increase of CCL4 and VEGF-A using qRT-PCR. In addition, we ...
12
LncRNAs in pancreatic cancer
... adjust angiogenesis in cancer by regulating the expression of hypoxia-inducible factorα (HIF1α) ...microvascular invasion in HCC (MVIH), was found to be up-regulated in HCC ...microvascular invasion, ...
12
NF κB as potential target in the treatment of melanoma
... Its role in the regulation of apoptosis, tumor angiogenesis and proliferation, as well as tumor cell invasion and metastasis indicates that this transcription factor may become a therape[r] ...
8
Paired box 8 suppresses tumor angiogenesis and metastasis in gastric cancer through repression of FOXM1 via induction of microRNA-612
... enhanced osteosarcoma metastasis [3]. Pax4 can pro- mote the invasion and metastasis of epithelial cancers by inhibiting the expression of microRNA (miR)-144 and miR-451 [5]. miRs are thought to act as a negative ...
11