Invasion and migration
Inhibition of invasion and migration of prostate cancer cells by miRNA-509-5p via targeting MDM2.
... To substantiate the relationship between miRNA-509-5p and MDM2 further, we performed the luciferase reporter assay. We observed reduced luciferase activity in HGC-27 cells co-transfected with MDM2 3'-UTR and ...
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Original Article MiR-23b inhibits cell migration and invasion through targeting PDE7A in colon cancer cells
... the invasion and metas- tasis of colon cancer by regulating PDE7A ...cell invasion and migration was determined by Transwell ...and invasion abilities of SW620 cells or SW480 ...the ...
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Original Article NUAK1 knockdown suppresses prostate cancer cell epithelial-mesenchymal transition, migration, and invasion through microRNA-30b-5p
... overexpression suppressed EMT, migration, and invasion in prostate cancer cells. Fur- thermore, we described that introduction of NUAK1 counteracted the miR-30b-5p-mediat- ed role, which also uncovered that ...
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<p>HNF1A-AS1 Regulates Cell Migration, Invasion and Glycolysis via Modulating miR-124/MYO6 in Colorectal Cancer Cells</p>
... cell migration and invasion are important processes in the treatment of ...including invasion and ...cell invasion and migration through regulating FOXO3 via sponging miR-96 in ...
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The inhibition role of miR-22 in hepatocellular carcinoma cell migration and invasion via targeting CD147
... RT‑PCR. Invasion assay, MTT proliferation assay and wound‑healing assay were performed to test the invasion and proliferation of HCC cell after overexpression of ...proliferation, migration and ...
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Roles of CXCL5 on migration and invasion of liver cancer cells
... proliferation, migration, and invasion [28] and to assist cancer cells in evading stress-induced apoptosis ...LCC migration and invasion when the concentration of CXCL5 in the environment ...
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The role of SH3GL3 in myeloma cell migration/invasion, stemness and chemo-resistance
... cell migration and invasion, we first overexpressed SH3GL3 in a myeloma cell ...cell migration (Figure ...enhanced migration and invasion of myeloma ...
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ECM1 promotes migration and invasion of hepatocellular carcinoma by inducing epithelial mesenchymal transition
... cell migration and invasion, the exact mechanisms by which ECM1 promoted tumor progression remained ...and migration and invasion are the main factors of recurrence of ...the migration ...
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RND3 promotes Snail 1 protein degradation and inhibits glioblastoma cell migration and invasion
... the migration and invasion of multiple tumors, including glioblastoma multiforme ...cell migration and invasion remains largely ...cell migration and ...glioblastoma migration ...
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Migration and invasion enhancer 1 (MIEN1) is overexpressed in breast cancer and is a potential new therapeutic molecular target.
... with migration and invasion in various types of cancer cells (Slamon et ...the migration and invasion of tumor cells in prostate cancer (Dasgupta et ...
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<p>lncRNA DSCAM-AS1 downregulates miR-216b to promote the migration and invasion of colorectal adenocarcinoma cells</p>
... Although miR-216b has been characterized as a tumor suppressor in many types of cancer, 13,14 the function of miR-216b in CRA is still controversial. Zou et al reported that miR-216b promoted cell growth in colon cancer, ...
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Original Article Retinol-binding protein 4 regulates the biological functions and molecular mechanisms of JEG-3 cells
... inadequate invasion of trophoblasts and spiral artery remo- deling [4, ...the invasion and migration capacities of EVTs and placental hypoperfusion, hypoxia, or isch- aemia may occur and thus induce ...
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Acidic Microenvironment Up-Regulates Exosomal miR-21 and miR-10b in Early-Stage Hepatocellular Carcinoma to Promote Cancer Cell Proliferation and Metastasis
... proliferation, migration, and invasion. MTT, invasion and migration assays showed that acidic HCC- derived exosomes significantly increased cell prolifer- ation, migration, and ...
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<p>Numb inhibits cell proliferation, invasion, and epithelial–mesenchymal transition through PAK1/β-catenin signaling pathway in ovarian cancer</p>
... cells’ invasion and migration were also ...the migration and invasion abilities were significantly promoted in PAK1- overexpressing cells while knocking down PAK1 yielded the opposite results ...
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Emerging role of LOXL2 in the promotion of pancreas cancer metastasis
... LOXL2, a member of the LOX family, is responsible for the stabilization of collagen and elastin fibers in ECM through covalent oxidative deamination. Tissue fibrosis is associated with cancer progression through direct ...
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MiR-206 suppresses epithelial mesenchymal transition by targeting TGF-β signaling in estrogen receptor positive breast cancer cells
... EMT inhibition caused by miR-206 overexpression. Interestingly, we found both TGF-β transcription level and the TGF-β autocrine production level were downregulated in the miR-206 overexpressing cell lines. We also found ...
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<p>Circular RNA circHIPK3 promotes cell proliferation and invasion of prostate cancer by sponging miR-193a-3p and regulating MCL1 expression</p>
... the migration and Transwell assays results, we also demonstrated that MCL1 overexpression significantly increased the migration and invasion of PCa cells and that circHIPK3 knockdown significantly ...
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Cross-linked hyaluronic acid gel inhibits metastasis and growth of gastric and hepatic cancer cells: in vitro and in vivo studies
... on migration, invasion, growth and implantation of gastric and hepatic cancer ...the migration and the invasion activities of gastric and hepatic cancer ...
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<p>Long Non-Coding RNA PVT1 Regulates BAMBI To Promote Tumor Progression In Non-Small Cell Lung Cancer By Sponging miR-17-5p</p>
... For migration, the lower chamber was added with RPMI-1640 medium containing 10% FBS while the upper chamber was fi lled with serum-free ...the invasion assay were similar with that in migration ...the ...
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SPANXA suppresses EMT by inhibiting c-JUN/SNAI2 signaling in lung adenocarcinoma
... vitro migration and matrigel invasion assay The migration and invasion abilities were determined using a Transwell apparatus without or with Matrigel-coated membranes (BD Biosciences, Franklin ...
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