ISATIN DERIVATIVES
Synthesis and α glycosidase inhibitory evaluation of isatin derivatives
... mixture was cooled to room temperature and then poured onto ice (250g). The solid was filtered out and dried over air to yield the crude which was purified by dissolving in dilute sodium hydroxide (5%, 100mL) followed by ...
5
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NEW ISATIN DERIVATIVES
... of isatin and 1,3,4 oxadiazole group at ...the isatin derivatives increases the antimicrobial activity, this is mostly due to increase cell permeability and hydrophobicity of bromo substituted ...of ...
5
A survey on the characterization and biological activity of isatin derivatives
... examined isatin derivatives against fungi is also important for they can be applied as antifungal ...the isatin derivatives synthesized in this research have displayed significant activity ...
22
Synthesis, Characterization, and Antimicrobial Activity of New Schiff’s and Mannich Bases of Isatin and Isatin Derivatives
... From the results in table 1, all the synthesized compounds showed moderate antibacterial activity against E. coli at 500µg/mL and most of them moderately active against K. pneumonia of the same concentration comparable ...
8
Design Synthesis, Characterization and Invitro Biological Evaluation of Novel Series of 1- Substituted Isatin Derivatives by Mannich Reaction.
... pharmaceuticals, isatin itself possesses an extensive range of biological ...activities. Isatin is able to participate in a broad range of synthetic reactions, leading to extensive use as a precursor ...
144
Facile synthesis of Schiff and Mannich bases of isatin derivatives
... indole derivatives which was prepared by oxidation of indigo 1 . Isatin Schiff’s bases are known to possess a wide range of biological activities such as antimicrobial, 2-8 antifungal, 9 anticancer, 10 anti ...
10
Design, synthesis and biological evaluation of N phenyl substituted isatin derivatives
... 7-substituted isatin derivatives possess a wide range of pharmacological activities and biological activities, such as anticancer, antibacterial [3-4], et ...4-substituted isatin derivatives ...
6
SYNTHESIS, CHARACTERIZATION, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF ISATIN DERIVATIVES
... Heterocyclic compounds have a wide range of application in the field of chemistry. The fusions of several rings resulting in polycyclic structures from biologically active heterocyclic templates are always of interest to ...
6
Synthesis and biological evaluation of some novel isatin derivatives as antimicrobial agents
... of isatin derivatives from isatin, malononitrile, and cyclic 1,3-dicarbonyl compounds using tetrabutylammonium bromide (TBAB) as an inexpensive, non-toxic, non-metallic and readily available catalyst ...
5
Facile method for the synthesis of silver nanoparticles using 3-hydrazino-isatin derivatives in aqueous methanol and their antibacterial activity
... hydrazino-isatin derivatives in an aqueous methanol reaction medium is reported ...3-hydrazino-isatin derivatives (3-hydrazino-isatin [IsH] and 1-benzyl-3-hydrazino-isatin ...
8
SYNTHESIS, CHARACTERISATION, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF ISATIN DERIVATIVES
... of isatin were synthesized by condensation of isatin molecule with different anilines after performing the molecular docking and ADME ...prediction. Isatin nucleus contains both the keto and lactam ...
8
Synthesis and Screening of New Isatin Derivatives
... of isatin derivatives and benzimidazole derivatives, it is planned to synthesize new isatin derivatives containing 1-H-benzimidazol-2yl methane-thiol moiety in one side chain at 3rd ...
7
Syntheses and Pharmacological Activities of Isatin Derivatives
... All the chemicals used in the synthesis of isatin derivatives were of synthetic grade and procured locally. Thin layer chromatography was used for monitoring the progress of reaction and product formation. ...
5
Synthesis, characterization and biological activity of novel spiroheterocycles from isatin derivatives
... sugar derivatives, β-lactams, aminoacids and ...Isooxazoline derivatives have been extended to many natural product synthesis and also proved to be an efficient precursor for many synthetic intermediates ...
7
Imide and isatin derivatives as β lactam mimics of β lactam antibiotics
... Method D: Isatin-N-α-acetoxyacetic acid methyl ester (22). Isatin-N-α-hydroxyacetic acid methyl ester 18 (2.0g, 8.5 mmol) was dissolved in pyridine (10 cm 3 ) with stirring and cooled to 0°C. Acetyl ...
20
EVALUATION OF ANTI-INFLAMMATORY ACTIVITIES OF NEWLY SYNTHESIZED ISATIN DERIVATIVES IN RATS
... new isatin-carbamate derivatives (3a-d) have synthesized previously by condensation isatin(2,3-indolinendione) with piperidine(hexahydropyridine), hydrazine hydrate and Boc-amino acids respectively ...
6
CYTOTOXIC ACTIVITY OF NOVEL ISATIN DERIVATIVES
... [8] M. Sarangapani amd V.M.Reddy, “ Synthesis and screening of Isatin-3-[N 2 - (alkoxyethyloxy) acetyl] hydrazones”, Indian drugs 36(6) June 1999(357-362). [9] G.J. Kapadia, Y.N. Shukla, S.P. Basak, E.A. Sokoloski ...
5
Synthesis and Pharmacological Evaluation of Some Novel Isatin Derivatives for Antimicrobial Activity
... that isatin possess diverse chemotherapeutic activities such as antibacterial [1], antifungal [2], antiviral [3], anti- HIV [4], anti-mycobacterial [5], anti cancer [6], anti- inflammatory [7] and anticonvulsant ...
5
Synthesis and Analgesic Activity of 1-(1-((Substituted) Methyl)-5- Methoxy-2-Oxoindolin-3-Ylidene)-4- (Substituted Pyridin-2-Yl)Thiosemicarbazide
... of isatin derivatives were synthesized by condensing the Schiff base of isatin derivative with formaldehyde and various secondary amines (Scheme ...
6
Synthesis, Characterization and DPPH Scavenging Assay of Isatin Related Spiroheterocyclic Compounds
... new isatin derivatives of Schiff bases, spiro-4- thiazolidiones, 5’-methyl-spiro-4-thiazolidiones have been successfully synthesized and evaluated for their antioxidant ...
5