Ischemia/Reperfusion (I/R)
ASSESMENT OF THE ANTI INFLAMMATORY EFFECT OF CINEOL ON CEREBRAL ISCHEMIA REPERFUSION I/R INJURY
... and reperfusion in the brain brings a inflammating reaction that is possibly exacerbating primary stages of tissue ...analytical I/R injury in rat model via interfering with ...cerebral ...
9
Effects of vagus nerve stimulation on cognitive functioning in rats with cerebral ischemia reperfusion
... cerebral ischemia/reperfusion (I/R) injury model in ...The I/R‑related injury was modeled using occlusion and reperfusion of the middle cerebral artery (MCAO/R) in ...
12
Pathophysiology of Ischemia/Reperfusion-induced Myocardial Injury: What We Have Learned From Preconditioning and Postconditioning?
... injury. I/R- induced leukocyte activation has been noted to release ROS, proteases and elastases, which result in increased microvascular permeability, edema, thrombosis, and cell death [ 11, 21, ...of ...
8
Original Article Cardioprotective role of curcumin in myocardial ischemia-reperfusion of male albino rats
... myocardial ischemia- reperfusion (I/R) model of male albino ...reduce ischemia-reperfusion based heart ...cardiac I/R damage. Myocardial I/R rat ...
9
Hepatic leukostasis and hypoxic stress in adhesion molecule deficient mice after gut ischemia/reperfusion
... of ischemia/reperfusion and ...bral ischemia followed by 22 h of reperfusion is associated with an accumulation of neutrophils, an increased ICAM-1 mRNA, and tissue necrosis in the mouse ...
9
Neuroprotective effect of Buyang Huanwu Decoction on spinal ischemia reperfusion injury in rats is linked with inhibition of cyclin dependent kinase 5
... that ischemia-reperfusion injury caused alterations of p25/p35, specifically in up- regulated expression of p25 and down-regulated expression of ...spinal ischemia- reperfusion triggered the ...
7
Cardiac mast cell–derived renin promotes local angiotensin formation, norepinephrine release, and arrhythmias in ischemia/reperfusion
... Having identified renin in cardiac mast cells, we assessed whether its release leads to cardiac dysfunction. In Langendorff-perfused guinea pig hearts, mast cell degranulation with compound 48/80 released Ang ...
9
Ischemic conditioning by short periods of reperfusion attenuates renal ischemia/reperfusion induced apoptosis and autophagy in the rat
... [20], ischemia/reperfusion injury enhanced both apopto- sis and autophagy production in the rat kidney and con- tributed to renal ...the ischemia/reperfusion model, autophagy and apoptosis are ...
10
Cromoglycate, not ketotifen, ameliorated the injured effect of warm ischemia/reperfusion in rat liver: role of mast cell degranulation, oxidative stress, proinflammatory cytokine, and inducible nitric oxide synthase
... Hepatic ischemia/reperfusion (ISCH/REP) is a major clinical problem that is considered to be the most common cause of postoperative liver ...Group I: SHAM (normal saline, intravenously [iv]); Group ...
10
The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment
... Japan). I/R or sham control brain tissues (n = 3 for sham or n = 4 for each treated group) were collected, and tis- sue samples were lysated, homogenized and protein con- centration was measured with ...
13
The cardioprotective effect of danshen and gegen decoction on rat hearts and cardiomyocytes with post ischemia reperfusion injury
... Over recent years, mitochondria have become a major research focus for experimental cardiologists. The ex- ploration of the potential role of mitochondria in the pathogenesis of cardiovascular diseases, particularly in ...
13
Attenuation of Focal Cerebral Ischemic Injury Following Post-Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat
... schemic brain injury is resulting from a complex sequence of pathophysiological events that is developed with time and space [1]. The extent of tissue damage occurring during stroke depends on both the duration and the ...
7
Download Download PDF
... cerebral ischemia, which were designed and synthesized to increase the penetrability and enzymatic stability of ...groups: I - Sham; II - Ischemia- reperfusion (I/R); III - ...
7
Reduction of Cardiac Cell Death after Helium Postconditioning in Rats: Transcriptional Analysis of Cell Death and Survival Pathways
... myocardial ischemia/reperfusion (I/R) it was shown that helium conditioning reduces infarct ...of ischemia and 5, 15 or 30 min of ...of I/R-induced cell ...versus ...
11
Hepatoprotective effects of limb ischemic post-conditioning in hepatic ischemic rat model and liver cancer patients via PI3K/ERK pathways
... organ ischemia makes it difficult to implement in clinical ...the ischemia/reperfusion (I/R) process ...for ischemia, and Zhao et ...5-min ischemia/ 1-min ...
14
Effect of Pioglitazone, Glimepiride and Nebivolol on Renal Marker in Renal Reperfusion Induced Renal Damage in Type 2 Diabetic Rats
... Renal ischemia/reperfusion (I/R) injury is a major cause of acute renal failure (ARF) (2), which is faced in many clinical situations such as kidney transplantation, partial nephrectomy, renal ...
12
C4d Deposition Reveals Myocardial Infarction After Cardiac Arrest – Experimental Study
... with ischemia- -reperfusion injury only (IRI; A), and a graft with ischemia-reperfusion injury and myocardial infarction (IRI + MI; B) 2 days after ...
7
Inhibition of mTOR Pathway by Rapamycin Reduces Brain Damage in Rats Subjected to Transient Forebrain Ischemia
... ebral ischemia was associated with inhibition of the mTOR ...after ischemia, which is likely caused by a low cellular energy state during the ischemic period ...cardiac ischemia and ...
12
Agent-based dynamic knowledge representation of Pseudomonas aeruginosa virulence activation in the stressed gut: Towards characterizing host-pathogen interactions in gut-derived sepsis
... lowing ischemia reperfusion injury was used in in vitro experiments to study the effects of endogenous opioids and ischemia byproducts on virulence expression in ...intestinal ischemia ...
34
Sphingosine-1-phosphate: distribution, metabolism and role in the regulation of cellular functions
... in ischemia- reperfusion events: S1P (1 and 10 mM) decreased infarct size and creatine kinase release while S1P or S1P(1)R-selective agonist SEW2871 was able to improve left ventricular developed ...
17