Isolated rat heart
Glycemia and the cardioprotective effects of insulin pre-conditioning in the isolated rat heart
... the isolated rat heart using the Langendorff ...the heart was paced at 222 beats/min. Measurements of heart rate, coronary flow and maximum of LV derivative of pressure development ...
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Evaluation of Inotropic Activity of Fluorobenzene Derivative Using an Isolated Rat Heart Model
... Analyzing this hypothesis, in this study the biologic activity of the compound 3 on reperfusion/injury was evaluated using an isolated heart model. The results (Figure 2) showed that the compound 3 reduced ...
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Fatty acid uptake by isolated rat heart myocytes represents a carrier mediated transport process
... The mechanism by which fatty acids enter cardiomyocytes is unclear. Therefore, the influx kinetics of [3H]oleate into isolated rat heart myocytes were examined. Cells were incubated at 37 degrees C ...
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An investigation on cardioprotective potential of Marrubium vulgare aqueous fraction against ischaemia-reperfusion injury in isolated rat heart
... the isolated rat heart along with its antioxidant activity. The phytochemical screening of the aqueous extract showed the presence of acteoside and proanthocya- nidins. Based on our findings, the ...
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Evaluation of Positive Inotropic Activity Induced bya Danazol Derivative in Isolated Rat Heart Model
... in isolated rat heart (Langendorff technique) was ...the isolated rat heart through of molecular me- chanism different than ...
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Original Article Nitric oxide donor, NOC7, reveals dose dependently and cGMP pathway independently biphasic effects on contractile force of isolated rat heart after global ischemia
... the isolated rat heart and main- ly embodied as concentration-dependent: The tiny concentration of NO donor can produce a positive inotropic effect and improve the cardi- ac function after myocardial ...
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Gradual Clamping Reduced Ischemia Reperfusion Injury in an Isolated Rat Heart Model
... The isolated perfused mammalian heart model was established in 1897 by Oscar ...the isolated mammalian heart preparation makes this model high reproducibility and relatively low cost, and a ...
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Allopurinol enhanced adenine nucleotide repletion after myocardial ischemia in the isolated rat heart
... Supplementation of the perfusion medium with hypoxanthine, the substrate for xanthine oxidase, maintained function and replenished ATP content to levels similar to that observed with all[r] ...
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Effects of interleukin 2 on cardiac function in the isolated rat heart
... Adoptive immunotherapy with IL 2 is associated with severe cardiovascular toxicities including peripheral and pulmonary edema, hypotension decreased systemic vascular resistance, increased heart rate, and an ...
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Novel insights into the cardio protective effects of FGF21 in lean and obese rat hearts
... the isolated rat heart Langendorff system, we measured left ventricular developed pressure (LVDP), relating to maximal rates of LV pressure decay; dP/dtmin and dP/dtmax (+/2dp/dt), a specific ...
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EVALUATION OF CARDIOTONIC ACTIVITY OF MORINGA OLEIFERA ROOTS
... follow: Isolated rat heart preparation using normal and hypodynamic Ringer Locke solution on Langendorff’s assembly, to evaluate cardiotonic activity as well as to find underlying mechanism of ...
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EPICARDIAL AUTOFLUORESCENCE NAD(P)H KINETICS IN THE ISCHEMICALLY PRECONDITIONED LANGERDORFF RAT HEART. EFFECTS OF CAPSAICIN. PART 1
... [34] Li Y, Kloner RA. Does protein kinase C play a role in ischemic preconditioning in rat hearts ?. Am J Physiol 1995; 268: H426-H431. [35] Lundmark JL, Ramasamy R, Vulliet PR, Schaefer S. Chelerythrine increases ...
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Antioxidant Activity of Ascorbic Acid on Ischemic and Reperfused Rat Heart
... In addition to this, Vitamin C acts as the first line of defence against oxidative stress during ischemia reperfusion cycle [1]. It is the only antioxidant in plasma capable of completely inhibiting oxidative ...
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EVALUATION OF CARDIOTONIC EFFECT OF HYDROALCOHOLIC LEAF EXTRACT OF NERIUM INDICUM: AN ANIMAL STUDY
... frog heart- the frog were sacrificed by pithing. hypodynamic heart developed with half calcium ringer ...on isolated rat heart-the rat was ...
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Cardiovascular activity of Labdane Diterpenes from andrographis paniculata in isolated rat hearts
... resting heart tension was adjusted to 2 g to the optimum contractile ...tension. Heart rate was also detected through this ...perfused isolated rat heart (PIH) was stabilised for about ...
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BIOLOGICAL EVALUATION OF ETHYL-2-METHYLQUINOLINE-3-CARBOXYLATE IN MYOCARDIAL ISCHAEMIA REPERFUSION INJURY
... perfused heart preparation has been employed in the present study because it permits the use of pharmacological interventions without any interference due to changes in systemic ...in heart following MI by ...
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Hypercholesterolemia downregulates autophagy in the rat heart
... adult rat hearts and that au- tophagy is necessary for cardioprotection by ischemic preconditioning ...whether isolated hypercholesterolemia modulates cardiac autophagy and mTOR pathways in ...
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SEQUESTRATION OF LEUKOCYTES BY THE ISOLATED PERFUSED RAT LUNG
... of rat leukocytes and bone marrow cells by the lung vasculature was studied using an isolated perfused rat lung ...the isolated perfused lung is a physiological process which can be considered ...
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Experimental glomerulonephritis in the isolated perfused rat kidney
... in isolated rat kidneys perfused at controlled perfusion pressure, pH, temperature, and flow rates with recirculating oxygenated perfusate containing bovine serum albumin (BSA) in buffer and sheep antibody ...
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Metabolism of reverse triiodothyronine by isolated rat hepatocytes
... by isolated rat hepatocytes was analyzed by Sephadex LH-20 chromatography, high performance liquid chromatography, and radioimmunoassay, with closely agreeing ...by rat hepatocytes is only observed ...
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