JC Virus
Glial Cell-Specific Regulation of the JC Virus Early Promoter by Large T Antigen
... polyomavirus JC virus is the etiologic agent of progressive multifocal leukoencephalopathy ...(PML). JC virus selectively destroys oligodendrocytes, leading to multiple areas of demyelination ...
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DNA from BK Virus and JC Virus and from KI, WU, and MC Polyomaviruses as Well as from Simian Virus 40 Is Not Detected in Non UV Light Associated Primary Malignant Melanomas of Mucous Membranes
... simian virus 40 (SV40), since some of these viruses are potentially neurotropic and melanocytes have a neuroepi- thelial ...BK virus (BKV) and JC virus (JCV) (10, 18) had been the only known ...
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Copy Number Heterogeneity of JC Virus Standards
... the JC virus reference genome in NCBI (GenBank accession number ...The JC virus plasmid pMAD1 contains a 4-kb backbone insert within this PCR ...a JC virus from a clinical urine ...
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Genotypes of John Cunningham (JC) Virus Urinary Excretion in Pregnant and Non-Pregnant Women in Isfahan, Iran
... of JC virus in different geographical areas is a useful tool for reconstructing of the genetic information and understanding of the evolution of the virus and also in tracing of the last and present ...
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NFAT4 Is Required for JC Virus Infection of Glial Cells
... polyomavirus JC virus (JCV) is the causative agent of a fatal central nervous system (CNS)-demyelinating disease known as progressive multifocal leukoencephalopathy (PML) ...common virus, with 70% of ...
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Molecular Cloning and Expression of Major Structural Protein VP1 of the Human Polyomavirus JC Virus: Formation of Virus-Like Particles Useful for Immunological and Therapeutic Studies
... polyomavirus JC virus (JCV), the causative agent of progressive multifocal leukoencephalopathy (PML), was expressed by using recombinant ...formed virus-like particles (VLP) with the typical ...
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Age-Specific Seroprevalence of Merkel Cell Polyomavirus, BK Virus, and JC Virus
... Using a newly developed VLP-based ELISA, we determined the age-specific seroprevalence of Merkel cell polyomavirus, a recently discovered human polyomavirus implicated in the eti- ology of Merkel cell cancer, and ...
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Functional comparison of PML-type and archetype strains of JC virus.
... of JC virus T antigen on early- gene expression could be detected, it was an inhibitory ...case, JC virus T antigen does not seem to be as strong an inhibitor of viral early-gene expression as ...
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Human fetal Schwann cells support JC virus multiplication.
... 1002 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The human papovavirus JC virus JCV, the etiologic agent of progressive multifocal leukoencephalopathy, displays a n[r] ...
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Genotyping of JC Virus in Clinical Samples in North Eastern Iran
... the JC virus in response to immunosuppressive drugs (32) and because PML is thought to be the source of cascading events that start with reactivation of JCV after immune suppression (6, ...between JC ...
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Dual Qualitative Quantitative Nested PCR for Detection of JC Virus in Cerebrospinal Fluid: High Potential for Evaluation and Monitoring of Progressive Multifocal Leukoencephalopathy in AIDS Patients Receiving Highly Active Antiretroviral Therapy
... out the role of potential inhibitors causing false-negative re- sults, an internal amplification control was constructed (pGem- bla; Materials and Methods, Fig. 1a) and included in all assays. The amplification of the ...
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Oligosaccharides as Receptors for JC Virus
... JC virus (JCV) belongs to the polyomavirus family of double-stranded DNA viruses and in humans causes a demyelinating disease of the central nervous system, progressive multifocal ...generated ...
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Comparison of infectious JC virus DNAs cloned from human brain.
... 299-308 0022-538X/83/010299-10$02.00/0 Copyright © 1983, American Society for Microbiology Comparison of Infectious JC Virus DNAs Cloned from Human Brain We cloned JC virus DNA obtained [r] ...
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JC virus detection and JC virus specific immunity in natalizumab treated Multiple Sclerosis patients
... allowing JC virus reactivation from ...for JC virus as other opportunistic infections are only occasionally reported in natalizumab- treated MS patients ...of JC virus within the ...
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JC virus in the pathogenesis of colorectal cancer, an etiological agent or another component in a multistep process?
... JCV is a human neurotropic polyomavirus, and neuro- logical diseases, such as progressive multifocal leukoence- phalopathy have been associated to JC virus [11,31]. Initial studies suggested that the ...
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JC Virus Infection of the Brain
... immunodeficiency virus; ICL ⫽ idiopathic CD4 lymphocytopenia; iPML ⫽ inflammatory PML; IRIS ⫽ immune reconstitution inflammatory syndrome; JCE ⫽ JCV encephalopathy; JCM ⫽ JCV meningitis; JCV ⫽ JC ...
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Differences in regulatory sequences of naturally occurring JC virus variants.
... That the common repeated sequence itself is important, as opposed to the core sequences of various enhancers 66, is suggested by the fact that the tandem repeat which altered the host ra[r] ...
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Brain tumors of owl monkeys inoculated with JC virus contain the JC virus genome.
... From analysis of the restriction endonuclease fragments, the two areas have cells that have common viral integration sites, but the second site of inoculation does not show all the sites[r] ...
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Detection of BK virus and JC virus in urine and brain tissue by the polymerase chain reaction
... These were i 11 urine specimens from renal allograft and bone marrow transplant recipients which were positive by in situ filter hybridization by using mixed BKV and JCV probes, ii 30 ur[r] ...
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JC Virus Evolution and Its Association with Human Populations
... If JCV had been transmitted primarily vertically and had codiverged with human populations, we would expect to see a strong geographical grouping of the viral isolates matching the structure of human populations, with ...
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