Key Player
Context-aware services in cooperative value chains: a key player-centred approach
... 5. Conclusions. So far, the potential of context-aware computing has been recognised only in a few industries such as manufacturing or retail in which some context-aware applications have been introduced. In several ...
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Macrophage Migration Inhibitory Factor (MIF): A Key Player in Protozoan Infections
... fined years ago, specific therapeutic or preventive interventions are not yet available, and better under- standing of the immune response to these protozoans is required. Recently, MIF has been considered a key ...
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Bronchial epithelium in children: a key player in asthma
... a key player in health and ...The key to promoting prevention at any stage of lung development will be the analysis of responses to microorganisms, allergens and ...
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Is Korea Ready to Be a Key Player in the Medical Tourism In-dustry? An English Education Perspective
... South Korea’s medical technology is world-class, but it is not a key player in the Asian medical tourism market. One of the biggest reasons that Korea is not one of the main destinations for medical tourism ...
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Adipose tissue as a key player in obstructive sleep apnoea
... conditions found in patients with severe OSA [18]. This IH condition, applied for at least 2 weeks, induces vascular dysfunctions and reproduces glucose and lipid homeostasis disturbances similar to those observed in OSA ...
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Myo9b is a key player in SLIT/ROBO mediated lung tumor suppression
... a key player in lung cancer and as a ROBO- interacting protein in what is, to the best of our knowledge, a newly defined SLIT/ROBO/Myo9b/RhoA signaling pathway that restricts lung cancer progression and ...
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Php4 Is a Key Player for Iron Economy in Meiotic and Sporulating Cells
... GGG031898 3077 3095 INVESTIGATION Php4 Is a Key Player for Iron Economy in Meiotic and Sporulating Cells Ariane Brault,* Charalampos Rallis,†,1 Vincent Normant,* Jean Michel Garant,* Jürg Bähler,† and[.] ...
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History and development of coronal mass ejections as a key player in solar terrestrial relationship
... Coronal mass ejections (CMEs) are relatively a recently discovered phenomenon—in 1971, some 15 years into the Space Era. It took another two decades to realize that CMEs are the most important players in solar ...
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Azoreductase: a key player of xenobiotic metabolism
... major player and an anaerobic pathway in which the azo compound reduction is mediated by reduced quinone compounds resulting from quinone reductase activities (Kudlich et ...
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The prostaglandin D2 receptor 2 pathway in asthma: a key player in airway inflammation
... IL-4 enhances the migration of eosinophils, which is a key step in the inflammatory cascade. To do this, in synergy with tumour necrosis factor (TNF)- α , IL- 4 increases the expression of vascular cell adhesion ...
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Is IgE or eosinophils the key player in allergic asthma pathogenesis? Are we asking the right question?
... Among structural cells, airway smooth muscle cells (ASMCs) have been considered for many years to only be involved in bronchoconstriction during acute exacer- bations of asthma. We need to underline that the activa- tion ...
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Circular RNAs in cancer: an emerging key player
... It has been reported that RNA-binding proteins (RBPs), such as RNA polymerase II [8], Argonaute [3], and MBL [50], can bind to circRNAs. In addition, several studies showed that circRNAs may play a role in the genesis ...
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Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer’s disease
... Synapse loss in forebrain, but not cerebellum, is a key hallmark of in Alzheimer’s disease. However, the mecha- nisms causing brain region-dependent synapse loss and protection are unknown. Here we provide ...
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Brachyury as a potential modulator of androgen receptor activity and a key player in therapy resistance in prostate cancer
... We showed that Brachyury overexpression in prostate cancer cells lines increased resistance to docetaxel and cabazitaxel drugs, whereas Brachyury abrogation induced decrease in therapy r[r] ...
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The alternative sigma factor SigF is a key player in the control of secretion mechanisms in Synechocystis sp. PCC 6803.
... The two holistic approaches used to evaluate the impact of SigF in Synechocystis physiology, namely the iTRAQ quantitative proteomic analysis and the in silico search for Accepted Articl[r] ...
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MST1, a key player, in enhancing fast skeletal muscle atrophy
... In the present study, we examined expression of MST1 in multiple striated muscles during postnatal development. We observed that the protein level of MST1 was enriched at early postnatal stages and dramatically declined ...
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PAFc, a Key Player in MLL-rearranged Leukemogenesis
... Aside from our identification of the PAFc-MLL interaction, several lines of evidence also indicate the direct role of PAFc in Hox gene dysregulation in MLL- rearranged leukemias. First, increasing evidence suggests that ...
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GLUCAN SYNTHASE-LIKE 8: A Key Player in Early Seedling Development in Arabidopsis
... Arabidopsis thaliana , callose, GLUCAN SYNTHASE-LIKE 8, cytokinesis, plasmodesmata, β-1,3-GLUCANASE, PLASMODESMATA-LOCALIZED PROTEIN 5,.. intercellular signaling, symplastic traff[r] ...
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Clusterin: a key player in cancer chemoresistance and its inhibition
... These data suggest that sCLU plays a significant role in tumor growth and metastatic progression in certain breast cancer cell lines.. The authors consider that knocking down sCLU g[r] ...
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The HBZ gene, a key player in HTLV 1 pathogenesis
... Lemasson I, Lewis MR, Polakowski N, Hivin P, Cavanagh MH, Thebault S, Barbeau B, Nyborg JK, Mesnard JM: Human T-cell leukemia virus type 1 HTLV-1 bZIP protein interacts with the cellular[r] ...
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