L-Asparaginase
Immunological responses to l asparaginase
... In a series of 40 patients treated with L-asparaginase for various neoplastic diseases, 6 patients had generalized anaphylactic reactions to L-asparaginase. Each of these reactors had ...
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Bench-scale production of l-asparaginase form erwinia carotovora in a laboratory fermenter
... in L-asparaginase ...of L-asparaginase by S. marcescens in 55 L scale ...of L-asparaginase by ...and L-asparaginase production by ...U) ...
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Role of L-Asparaginase as an Effective Chemotherapeutic agent for Acute Lymphoblastic Leukemia in Children’s
... immunological reactions to a foreign protein or due to events taking place in the body due to inhibition of protein synthesis. The toxicity levels are almost similar for the enzyme from different preparations. ...
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Isolation and Characterization of L- Asparaginase Producing Endophytic Bacteria from Simarouba Gluaca
... study, L-asparaginase enzyme is produced from Bacillus species which sustain as endophytes in certain species of plants which have anticancer ...produces L- asparaginase are Erwinia corotovora ...
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Scale-Up Studies on Microfiltration of Bacterial Broth Containing L-Asparaginase Enzyme
... of L-asparaginase ...of L -Asparagine by crude enzyme solution was estimated using Nessler’s Reagent in spectrometric analysis at 480 ...of L-asparaginase activity is defined as the ...
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ISOLATION AND SCREENING OF L- ASPARAGINASE PRODUCING BACTERIA FROM VISAKHAPATNAM SOIL SAMPLES
... L-asparaginase (E.C No 3.5.1.1) is a potential anti-carcinogenic enzyme. Six different soil samples of Vishakhapatnam regions were screened for potential producers of L-asparaginase using ...
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Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis in vitro and in vivo
... coli-derived L-asparaginase on a number of different glioma cell cultures including patient-derived xenograft (PDX) and stem cell-like glioma ...to L-asparaginase in contrast to LN229 GBM ...
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Enhancement of L-asparaginase Production by Candida utilis in a 13L Fermenter and its Purification
... of asparaginase enzyme dates back to 1922, when clementi reported the presence of the enzyme in blood of guinea pig serum ...of asparaginase enzyme [3]. Asparaginase enzyme catalyzes the hydrolyses ...
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Production and optimization of L asparaginase by E coli ATCC10536 from food waste
... for L-asparaginase production by ...of L-asparaginase enzyme, so there is no previous ...for L- asparaginase production by Serratia ...of L-asparaginase.[10]. ...
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L ASPARAGINASE: AN ULTIMATE ANTI NEOPLASTIC ENZYME ISOLATED FROM BACILLUS SPECIES
... L- asparaginase is enzyme acting on L- asparagine and is widely used as anticancer ...- L-asparaginase from Bacillus species from ...Potential L-asparginase producer isolates ...
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Production of l asparaginase as anticancer agent by alomonasalkaliantarctica isolated from marine samples
... Halomonas alkaliantarctica. (Kalyanasundarram et al., 2015) reported, the presence of nitrogen sources along with nitrogenous compounds present in the substrate promotes enhanced growth and consequent enzyme production. ...
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Pterostilbene Enhances Anticancer Effects of L-asparaginase in Lymphoblastic Leukemia Cell Line
... with L-asparaginase in Jurkat cell ...with L-asparaginase for 24, 48 and 72 ...IU/ml L-asparaginase reduced relative cell growth to a significant ...IU/ml ...
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Improved Biological Activity and Stability of enzyme L-Asparaginase in Solid Lipid Nanoparticles Formulation
... Enzyme L-Asparaginase is used specifically in the treatment acute lymphoblastic ...leukaemia. L-Asparaginase is well known for its ability to catalyse the biochemical reaction that converts ...
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Media optimization and growth parameters for the production of L asparaginase enzyme from bacterial isolate
... The strain is isolated from the soil samples of RVCE. The screened bacterial isolate [Fig 1] that produces L- asparaginase was employed for the present study. The isolate was sub cultured on nutrient agar ...
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A SIMPLE AND EFFICIENT DYE-BASED TECHNIQUE FOR RAPID SCREENING OF FUNGI FOR L-ASPARAGINASE PRODUCTION
... of L-asparaginase in pharmaceutical and food industries in general and favorable characteristics of L-asparaginase derived from fungal sources; there has been a constant search for ...
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STUDY ON PRODUCTION, PURIFICATION AND CHARACTERISATION OF L-ASPARAGINASE FROM ESCHERICHIA COLI AND PSEUDOMONAS AERUGINOSA
... of L- asparaginase using modified M-9 medium plate ...indicate L-asparaginase producing ...of L-asparaginase was produced when pseudomonas aeruginosa was grown in the modified ...
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Effect of Nutritional Factors on Growth and L-asparaginase Production by Three Thermophilic Caprophilous Fungi
... and L-asparaginase production by three species of thermophilic caprophilous fungi was studied by substituting L-asparagine so as to supply equal amount of nitrogen of yeast extract starch (YES) ...
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Strain improvement of isolated bacillus subtilis strain HSWX88 for extracellular l-asparaginase production
... The methods available to applied genetics involved trial and error. The major motivation for industrial strain development is economic, since the metabolic concentrations produced by wild strains are usually too low for ...
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The genus Fusarium as source of the anti leukemic enzyme l asparaginase: adjustment of the productive conditions
... enzyme L-asparaginase is used to avoid acrylamide formation in food, and as a pharmaceutical to treat Acute Lymphoblastic ...fungal L-asparaginase as an alternative to the bacterial enzymes ...
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A molecular genetic analysis of L asparaginase II synthesis in Erwinia Chrysanthemi NCPPB 1066
... of L-asparagine-requiring tumours. Indeed, only the L- asparaginase from ...of L- asparagine does not become rate-limiting In protein synthesis until it is reduced to ...coll ...
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