lamin A/C
The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer
... A, lamin B and lamin B receptor (LBR), are nuclear proteins that are found on the inner side of the nuclear ...and C make up the nuclear lamina, interacting with many integral membrane proteins of ...
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Reduced expression of lamin A/C correlates with poor histological differentiation and prognosis in primary gastric carcinoma
... of lamin A/C between tumour and control was made with Paired-samples t-test in all ...of lamin A/C expression with various clinicopathological parameters was calculated with Chi- square test ...
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Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C–deficient mice
... LV, LA, and skeletal muscle are more extensive than reported previously in hepatocytes (25), suggesting that structural defects in the lamina may render the nucle- us more susceptible to deformation within a contrac- ...
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Interruption of progerin–lamin A/C binding ameliorates Hutchinson Gilford progeria syndrome phenotype
... 6, C and ...from lamin A, may lose its ...of lamin A–progerin but not on that of lamin A–lamin ...of lamin A and progerin by JH4 in human ...from lamin A/C was ...
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Nuclear accumulation of UBC9 contributes to SUMOylation of lamin A/C and nucleophagy in response to DNA damage
... that lamin A/C could be a target of SUMOylation medi- ated by UBC9 ...that lamin A/C was SUMOylated by ...or lamin A/C, suggesting that UBC9 interacts with lamin ...of ...
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Effects of Lamin A/C, Lamin B1, and Viral US3 Kinase Activity on Viral Infectivity, Virion Egress, and the Targeting of Herpes Simplex Virus UL34-Encoded Protein to the Inner Nuclear Membrane
... of lamin A/C have been described previously ...talized lamin A/C knockout mouse embryonic fibroblast (MEF) cell line lacking the gene encoding lamin A/C (LmnA ⫺/⫺ ) was a gift ...
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Late gadolinium enhanced cardiovascular magnetic resonance of lamin A/C gene mutation related dilated cardiomyopathy
... also non-CAD pattern was documented in seven sub- jects [20]. A healthy control group of DCM patients in study by Zimmerman et al [18] showed no myocardial LGE. As LGE imaging is widely used as a gold standard in cardiac ...
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SUN2 Modulates HIV 1 Infection and Latency through Association with Lamin A/C To Maintain the Repressive Chromatin
... a C-terminal hemagglutinin (HA) tag was cloned into the ...the C-terminus deletion [SUN2(1–334)- and SUN2(1–189)-containing mutant] were constructed from the ...3=; lamin A/C shRNA, 5= CAT GGG ...
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US3 of Herpes Simplex Virus Type 1 Encodes a Promiscuous Protein Kinase That Phosphorylates and Alters Localization of Lamin A/C in Infected Cells
... of lamin A/C isoforms from mock-infected and HSV-infected ...against lamin A/C or a rabbit antibody against lamin B1 and lamin ...of lamin B-specific spots and by distance ...
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Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction
... lack lamin A and lamin C, most human diseases arise from heterozygous lamin ...mutant lamin often appears as stable as WT lamin and is expressed at similar levels ...of ...
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Circulation autoantibody against Lamin A/C in patients with Sjögren’s syndrome
... expression. Lamin A/C has been confirmed as an autoantigen in RA, SLE and ...confirm Lamin A/C is an autoantigen in Han Chinese patients with confirmed Sjögren’s syndrome ...of Lamin ...
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Original Article Investigation of splicing changes and post-translational processing of LMNA in sporadic inclusion body myositis
... proteins lamin A/C through alternative splicing, and aberrant splicing of exon 11 leads to the premature ageing disease, Hutchinson-Gilford progeria ...towards lamin A-related transcripts, which was ...
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The cancer-testis antigens SPANX-A/C/D and CTAG2 promote breast cancer invasion
... SPANX-A/ C/D was causal in supporting metastasis or epiphenomenon was not ...SPANX-A/ C/D proteins are 97 amino acids in length and do not have predicated enzymatic functions, suggesting that SPANX- ...
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Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer
... for lamin A/C expression by ...uniform lamin A/C staining around the nuclear envelope of all ovarian surface epithelial cells (Figure ...lack lamin A/C expression in epithelial ...
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Nuclear Connectivity in Mesenchymal Stem Cell Differentiation and its Role in Mechanotransduction
... does an amazing job keeping chaotic aspects of the Mauck lab at bay. Without her I know that many of my experiments would not have gone as smoothly as they did. Brian Cosgrove has established protocols for traction force ...
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From Engineering of Tumor Shrinking Dds to Engineering the Nucleus for Tumor Growth
... undetectable Lamin-A,C level and increase the expression along differentiation ...but Lamin-A,C expression ...nucleus. Lamin-A,C is connected to the cytoskeleton (actin ...
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Human Cytomegalovirus UL97 Phosphorylates the Viral Nuclear Egress Complex
... of lamin A/C by ...typical lamin A/C thinning and deformities in AA mutant-infected cells, we infer that the substitutions affect a step of nuclear egress other than lamina ...
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Human Cytomegalovirus Protein pp71 Disrupts Major Histocompatibility Complex Class I Cell Surface Expression
... a lamin a/c-specific RNAi ...or lamin a/c-specific RNAi duplexes did not appreciably alter cell surface MHC class I levels in unin- fected cells, and mock transfection resulted in only ...
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Diversity of high risk human papilloma viruses in women treated with antiretroviral and in healthy controls and discordance with cervical dysplasia in the South of Benin
... and lamin A/C analyses, a dis- posable sterile speculum was introduced in the vagina along with a disposable cytobrush to reach the cervical- uterine junction where cells were collected by rotating the ...
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Molecular Genetic Analysis of the Nested Drosophila melanogaster Lamin C Gene
... to lamin aggregations observed in mammalian cell culture upon overexpressing human lamin rod domain mutants (O stlund et ...2003). Lamin aggregration phenotypes, including O-ring structures, are ...
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