Large cell lung cancer
Identification of lipid-phosphatidylserine (PS) as the target of unbiasedly selected cancer specific peptide-peptoid hybrid PPS1
... HCC4017 lung cancer cells but not normal HBEC epithelial cells ...other lung cancer cell lines and the activity profile of PPS1D1 on those cell ...of lung cancer ...
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Large-cell neuroendocrine carcinoma of lung with epidermal growth factor receptor (EGFR) gene mutation and co-expression of adenocarcinoma markers: a case report and review of the literature
... in cancer reduction and quality of life improvement in patients with advanced NSCLC harboring EGFR gene ...of Lung Cancer/American Thoracic Society/European Respiratory Society about lung ADC ...
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Large bilateral adrenal metastases in non small cell lung cancer
... primary lung site is surgically resectable (T1, T2 and maybe T3), with no involvement or the involvement of only the peribronchial and portal lymph nodes (N0, N1) and where the adrenal metastasis constitutes the ...
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TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens
... Signals were recognized in the cytoplasm and occasionally in nuclei of tumor cells. There was a conspicuous amount of signal-containing alveolar macrophages and alveolar epithelial cells type II (AEC II cells), observed ...
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Endoplasmic reticulum Ca2+-homeostasis is altered in small and non-small cell lung cancer cell lines
... small cell lung carcino- mas to origin from neuro-epithelial ...of large cell carcinomas and adeno carcinomas is less ...malignant cell lines with, we decided to use normal human ...
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Multiplexed methylation profiles of tumor suppressor genes and clinical outcome in lung cancer
... of cancer- related genes may be essential for the diagnosis, prog- nosis and/or detection of metastatic potential of tumors, including lung ...in cancer is large and increasing, sensitive and ...
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Superior vena cava syndrome in a patient with locally advanced lung cancer with good response to definitive chemoradiation: a case report
... non-small cell lung cancer who had no clinical symptoms of superior vena cava syndrome at the time of ...her large right hilar primary ...
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Non-small cell to small cell lung cancer on PD-1 inhibitors: two cases on potential histologic transformation
... in the left hilar region occluding the left mainstem bronchus, hypermetabolic lesions (SUV 6.6) on both sides of the medi- astinum and a large left-sided pleural effusion. MRI brain did not show metastasis. He was ...
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Mutational and gene fusion analyses of primary large cell and large cell neuroendocrine lung cancer
... in lung cancer today ...studies, lung cancer patients with tumors harboring ROS1 or RET gene fusions have shown notable responses to ALK or other multi-target kinase inhibitors [28, ...
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Pathological transition as the arising mechanism for drug resistance in lung cancer
... small cell lung cancer; NSCLC: non-small cell lung cancer; ADC: adenocarcinoma; SCC: squamous cell carcinoma; LCC: large cell carcinoma; TTF1: thyroid ...
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Nitrilase 1 modulates lung tumor progression in vitro and in vivo
... human lung cancer and normal tissue microarrays (BC01115b, US BioMax, ...of lung squamous cell carcinoma (2 lung adenosquamous carcinomas), 44 lung adenocarcinoma, 4 each of ...
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SYNTHESIS AND PRELIMINARY EVALUATION OF NOVEL 1, 5-BENZOTHIAZEPINE DERIVATIVES AS ANTI-LUNG CANCER AGENTS
... In summary, we have developed a new series of 1,5- benzothiazepine derivatives. Our method has many advantages over existing conventional method, including high yield, simple work-up, shorter reaction span, no side ...
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Original Article Methylation of PRDM2, PRDM5 and PRDM16 genes in lung cancer cells
... for cancer diagnos- tics and treatment ...noma cancer cell line) and HTB-182 (lung can- cer cell line) as the experimental model, with HBE (normal bronchial epithelium cell line) ...
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Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo
... The effect of TQ on tumor cell invasion was assayed using a Matrigel based assay. Trans well inserts (Corn- ing Life Science, Corning, NY) with 8 micron diameter pores were coated with 20 μL of Matrigel (BD Bios- ...
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<p>MicroRNA-30a-3p inhibits the progression of lung cancer via the PI3K/AKT by targeting DNA methyltransferase 3a</p>
... suppressed cell growth, arrest of the G1 phase and inhibited apoptosis (Figure 5C – ...with cell cycle and ...the cell cycle regulators CDK2 and cyclin D were reduced by siDNMT3a, whereas those ...
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17α-Ethynylestradiol and 4-Nonylphenol Stimulate Lung Adenocarcinoma Cells Production in Xenoestrogenic Way
... 1. Wang, S.; Sun, T.; Sun, H.; Li, X.; Li, J.; Zheng, X.; Mallampati, S.; Sun, H.; Zhou, X.; Zhou, C., et al. Survival improvement in patients with non-small cell lung cancer between 1983 and 2012: ...
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ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer
... primary cancer samples and correlate expression with ZAR1 promoter methylation but also study interacting partners, which would give insight into its network and signalling path- ...somatic lung cells, as ...
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Scriptaid overcomes hypoxia-induced cisplatin resistance in both wild-type and mutant p53 lung cancer cells
... S2B). Cell cycle analysis using flow cytometry showed a G2-M and S-phase arrest at lower doses of cisplatin and a dose-dependent increase in cell death in normoxic ...conditions, cell cycle arrest ...
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Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment
... on lung malignancy, we performed cDNA microarray analysis to identify genes whose expression was coregulated by WDR4 overexpres- sion and PML knockdown in the A549 lung cancer cell ...healing, ...
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An adherent subline of a unique small cell lung cancer cell line downregulates antigens of the neural cell adhesion molecule
... However, expression of the neuroendocrine marker neuron-specific enolase in the floating cells was three times that found in the adherent cells. The floating subline also had much greater surface expression of ...
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