Latent Membrane Protein
Latent membrane protein 1 (LMP1) expression in Hodgkin lymphoma and its correlation with clinical and histologic parameters
... tent membrane protein 1 (LMP1), LMP2a, EBV nuclear antigen 1 (EBNA1), EBV small nuclear RNA transcripts (EBER), and the BamHI A region transcripts ...of latent membrane protein 1 (LMP1) ...
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Latent Membrane Protein 1 of Epstein-Barr Virus Inhibits as Well as Stimulates Gene Expression
... The latent membrane protein 1 (LMP-1) of Epstein-Barr virus (EBV) functionally resembles a constitutively active, CD40-like receptor and contributes to the maintenance of proliferation of ...
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Two Pathways of p27Kip1 Degradation Are Required for Murine Lymphoma Driven by Myc and EBV Latent Membrane Protein 2A
... (EBV) latent membrane protein 2A (LMP2A), expressed in EBV latency, contributes to Burkitt lymphoma (BL) development in a murine model by acting as a constitutively active B cell receptor (BCR) ...
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Interferon Regulatory Factor 7 Is Induced by Epstein-Barr Virus Latent Membrane Protein 1
... cases latent membrane protein 2A (LMP-2A), is expressed in this form of latency (7, 35, 36, 41, ...integral membrane proteins (LMP-1, LMP-2A, and LMP-2B), are ex- ...
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Epstein Barr virus latent membrane protein 1 suppresses reporter activity through modulation of promyelocytic leukemia protein nuclear bodies
... encoded Latent Membrane Protein 1 (LMP1) has been shown to increase the expression of promyelocytic leukemia protein (PML) and the immunofluorescent intensity of promyelocytic leukemia nuclear ...
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MUC1 Induced by Epstein-Barr Virus Latent Membrane Protein 1 Causes Dissociation of the Cell-Matrix Interaction and Cellular Invasiveness via STAT Signaling
... express latent membrane protein 1 (LMP1), the main viral oncoprotein, and that the level of MUC1 was suppressed by expression of a dominant-negative mutant of ...
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Epstein-Barr Virus Latent Membrane Protein 2A Contributes to Anoikis Resistance through ERK Activation
... the latent membrane protein 2A (LMP2A) is responsible for induc- tion of ERK-mediated anoikis resistance, although the expression level of LMP2A is much lower in EBV-positive cells than in ...
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A Membrane Leucine Heptad Contributes to Trafficking, Signaling, and Transformation by Latent Membrane Protein 1
... Latent membrane protein 1 (LMP1) of Epstein Barr virus (EBV) is important for maintaining proliferation of EBV-infected B ...first membrane-spanning domain that was shown to be necessary for ...
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Epstein-Barr Virus Regulates STAT1 through Latent Membrane Protein 1
... viral protein, a limited viral protein expression termed latency ...EBV latent genes—EBNA1, EBNA2, EBNA 3A, EBNA 3B, EBNA 3C, EBNA-LP, latent membrane protein 1 (LMP-1), and ...
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EBV latent membrane protein 1 abundance correlates with patient age but not with metastatic behavior in north African nasopharyngeal carcinomas
... nuclear protein called EBNA1 (Epstein-Barr nuclear antigen 1) detected in all NPC biopsies and visualized in the major- ity of malignant ...EBV protein called LMP1 (Latent membrane ...
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Latent Membrane Protein 1 Is a Novel Determinant of Epstein-Barr Virus Genome Persistence and Reactivation
... (EBNA1) protein is required for tethering EBV episomes to cellular DNA and for mitotic segre- gation to daughter ...EBV latent membrane protein 1 (LMP1) is an onco- genic signaling ...
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Epstein-Barr virus latent membrane protein 2 associates with and is a substrate for mitogen-activated protein kinase.
... The latent membrane protein 2 (LMP2) of Epstein-Barr virus interferes with B-lymphocyte signal trans- duction through the immunoglobulin (Ig) ...fusion protein containing the 119 amino acids ...
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Maintenance of Epstein-Barr Virus Latent Status by a Novel Mechanism, Latent Membrane Protein 1-Induced Interleukin-32, via the Protein Kinase Cδ Pathway
... EBV latent membrane protein 1 (LMP1) is responsible for inducing IL-32 expression at the mRNA and protein ...activator protein kinase C␦ (PKC␦) and inhibits its translocation from the ...
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Epstein-Barr Virus Latent Membrane Protein 2B (LMP2B) Modulates LMP2A Activity
... Latent membrane protein 2A (LMP2A) and LMP2B are viral proteins expressed during Epstein-Barr virus (EBV) latency in EBV-infected B cells both in cell culture and in ...
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Induction of Epstein-Barr Virus Latent Membrane Protein 1 by a Lytic Transactivator Rta
... Latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV) is a transforming protein that affects multiple cell signaling pathways and contributes to EBV-associated ...lytic protein ...
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Latent Membrane Protein 2B Regulates Susceptibility to Induction of Lytic Epstein-Barr Virus Infection
... of latent membrane protein 2 (LMP2), LMP2A and LMP2B, which are expressed during latency in B ...its latent to its lytic form upon BCR cross-linking, as indicated by a more-enhanced ...
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Latent Membrane Protein 2A-Mediated Effects on the Phosphatidylinositol 3-Kinase/Akt Pathway
... (EBV) latent membrane protein 2A (LMP2A) is expressed on the membranes of B lymphocytes and blocks B-cell receptor (BCR) signaling in EBV-transformed B lymphocytes in ...The protein kinase Akt ...
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Tumor Suppressor p53 Stimulates the Expression of Epstein-Barr Virus Latent Membrane Protein 1
... ABSTRACT Epstein-Barr virus (EBV) is associated with multiple human malignancies. EBV latent membrane protein 1 (LMP1) is required for the efficient transformation of primary B lymphocytes in vitro ...
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The Epstein-Barr virus latent membrane protein 1 regulates gene expression by engaging multiple signaling pathways
... others. Latent membrane protein 1 (LMP1), which is expressed in latency type II and III, is considered the EBV oncoprotein due to its ability to transform rodent fibroblasts and its critical roles in ...
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Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1.
... i Acute transfection and expression of EBNA-2 under control of simian virus 40 or Moloney murine leukemia virus promoters resulted in increased LMP1 expression in P3HR-1-infected Burkitt[r] ...
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