latent membrane proteins 1
Identification of a Spliced Gene from Kaposi’s Sarcoma-Associated Herpesvirus Encoding a Protein with Similarities to Latent Membrane Proteins 1 and 2A of Epstein-Barr Virus
... a latent form, with only a limited set of viral genes expressed in a tissue-specific ...encode membrane proteins with similarities to the LMP2A and LMP1 proteins of Epstein-Barr ...for ...
11
Epstein-Barr Virus Represses the FoxO1 Transcription Factor through Latent Membrane Protein 1 and Latent Membrane Protein 2A
... of proteins mediating lymphocyte apoptosis and differentiation, and bcl-6 transcription is activated by FoxO1 ...lines. Proteins were resolved by SDS-PAGE and immunoblotted with the anti-FoxO1 ...either ...
9
Tumor Suppressor p53 Stimulates the Expression of Epstein-Barr Virus Latent Membrane Protein 1
... IRF5 is associated with p53-mediated induction of LMP1. The LMP1 promoter region does not contain an obvious p53 binding site based on bioinformatics analyses (data not shown). It is suspected that p53 may use one or ...
14
A Membrane Leucine Heptad Contributes to Trafficking, Signaling, and Transformation by Latent Membrane Protein 1
... two membrane-spanning domains of LMP1 or LZ1 tagged with either GFP or mRFP (termed wt 1-2TM and LZ1 1-2TM) because they were suffi- cient for targeting to lipid rafts (6, ...Wt 1-2TM and LZ1 ...
10
Regulation of Latent Membrane Protein 1 Signaling through Interaction with Cytoskeletal Proteins
... between proteins, including LMP1-TRAF BiFC ...binding proteins are functionally related in LMP1 signaling, then BiFC should be sensitive to mutations in CTAR1 and/or ...actin-binding proteins, BiFC ...
14
Characterization of the latent membrane protein 1 signaling complex of Epstein Barr virus in the membrane of mammalian cells with bimolecular fluorescence complementation
... fusion proteins with the amino-terminus of YFP (NYFP) or the carboxyl-terminus of YFP ...fusion proteins with CYFP at the amino-termini, CYFP-TRAF2 and CYFP-TRAF3, were ...
15
Epithelial Cell Adhesion to Extracellular Matrix Proteins Induces Tyrosine Phosphorylation of the Epstein-Barr Virus Latent Membrane Protein 2: a Role for C-Terminal Src Kinase
... basement membrane occurs. Differentiating cells detach from the basement membrane and form the upper layers of the epithelium. At the same time, integrin expression is downregu- lated and the cellular ...
9
Epstein-Barr Virus Regulates STAT1 through Latent Membrane Protein 1
... 171 is an EBV-immortalized LCL derived from the same pa- tient as BL41. The second set consists of Mutu I and Mutu III (16). These are two sublines from an EBV-positive BL tumor. Mutu I expresses only the EBNA1 viral ...
5
Oncogenic Activity of Epstein-Barr Virus Latent Membrane Protein 1 (LMP-1) Is Down-Regulated by Lytic LMP-1
... from 1:1 to 10:1 did not necessarily increase the quantity of lyLMP-1 expressed in each individual cell, but it did significantly increase the number of cells in which lyLMP-1 was ...
9
Latent Membrane Protein 1 Is a Novel Determinant of Epstein-Barr Virus Genome Persistence and Reactivation
... antigen 1 (EBNA1) protein is required for tethering EBV episomes to cellular DNA and for mitotic segre- gation to daughter ...EBV latent membrane protein 1 (LMP1) is an onco- genic signaling ...
11
Induction of Epstein-Barr Virus Latent Membrane Protein 1 by a Lytic Transactivator Rta
... fusion proteins with full-length (amino acids 1 to 605), carboxyl-terminally truncated (amino acids 1 to 441), or amino-terminally truncated (amino acids 100 to 605) ...
9
Strong Selective Pressure for Evolution of an Epstein-Barr Virus LMP2B Homologue in the Rhesus Lymphocryptovirus
... references 1 and ...for latent infection nuclear proteins (EBNA-LP, -1, -2, -3A, -3B, and -3C) and membrane proteins (LMP1 and LMP2A) have been conserved in baboon and rhesus ...
6
Interferon Regulatory Factor 7 Is Induced by Epstein-Barr Virus Latent Membrane Protein 1
... antigen 1 (EBNA-1), and in some cases latent membrane protein 2A (LMP-2A), is expressed in this form of latency (7, 35, 36, 41, ...viral proteins, in- cluding six nuclear ...
8
The Epstein-Barr virus latent membrane protein 1 regulates gene expression by engaging multiple signaling pathways
... among these suggested mechanism is that they are all proteasome-dependent. The data presented here indicate that CTAR1 indeed induces processing of p50, which is consistent with previous studies (43). Proteasome ...
212
Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer
... LMP-1: Latent membrane protein 1; LMP-2A: Latent membrane protein 2A; EBER-1: EBV encoded small RNAs-1; EBER-2: EBV encoded small RNAs-2; BARF1: BamHI-A Reading ...
13
Strategies for the purification of membrane proteins
... organisms like yeast or bacteria and plant cells are more difficult to disrupt. Different techniques for breaking down cell walls include glass bead milling, grinding mills, homogenization, ultrasonication, osmotic ...
22
Characterization of Two Putative Protein Translocation Components in the Apicoplast of Plasmodium falciparum
... PfsDer1- 1-HA detect three HA-positive proteins ...inner membrane TPT protein, PfiTPT (20), and the ...apicoplast membrane protein FtsH1 (12, 13), but the sequence of events and what proteases ...
9
Abstract: In order to alter and adjust the shape of the membrane, cells harness various mechanisms of curvature
... of membrane curvature generation due to protein interactions in different continuum elastic ...with membrane produces a spontaneous curvature ...conical proteins on one side of the membrane ...
21
Latent Membrane Protein 1 of Epstein-Barr Virus Inhibits as Well as Stimulates Gene Expression
... in latent infection of resting B cells in cell ...in latent infection are indicated by arrowheads, with the primary RNA transcripts generated from these promoters indicated by dashed lines and the open ...
7
Deletion of DNA encoding the first five transmembrane domains of Epstein-Barr virus latent membrane proteins 2A and 2B.
... The last seven transmembrane and carboxy-terminal cytoplasmic domains of Epstein-Barr virus latent membrane 2 LMP2 are dispensable for lymphocyte infection and growth transformation in v[r] ...
7