Leishmania (L.) amazonensis
Essential oils: in vitro activity against Leishmania amazonensis, cytotoxicity and chemical composition
... Background: The current chemotherapy for cutaneous leishmaniosis (CL) has a series of drug limitations such as toxic side effects, long duration, high costs and drug resistance, which requires the development of new ...
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The use of kDNA minicircle subclass relative abundance to differentiate between Leishmania (L ) infantum and Leishmania (L ) amazonensis
... the Leishmania (Leish- mania) and Leishmania (Viannia) subgenera could be distinguished by exploiting kDNA variability through HRM analysis of qPCR-ML amplicons ...different Leishmania species were ...
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IL 32γ promotes the healing of murine cutaneous lesions caused by Leishmania braziliensis infection in contrast to Leishmania amazonensis
... Leishmania (L.) amazonensis (MHOM/BR/1973/ M2269) and L. (V.) braziliensis (MHOM/BR/2003/IMG) strains were obtained from patients with localized cuta- neous lesions [19, 20]. L. ...
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Resistance of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensisto nitric oxide correlates with disease severity in Tegumentary Leishmaniasis
... Leishmaniasis is a parasitic disease caused by the Leishma- nia spp. protozoa, transmitted to the skin of a mammalian host during the bite of an infected female sand fly vector. Infections range in severity from ...
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In vitro activity of Morinda citrifolia Linn fruit juice against the axenic amastigote form of Leishmania amazonensis and its hydrogen peroxide induction capacity in BALB/c peritoneal macrophages
... against L. infantum chagasi [7] and Leishmania amazonensis [8], however, the activity against axenic amastigote has not yet been ...against L. amazonensis correlated macrophage acti- ...
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Impact of reactive oxygen species (ROS) on the control of parasite loads and inflammation in Leishmania amazonensis infection
... genus Leishmania: some parasites are susceptible to their action, while others seem to be ...in L. amazonensis infection in vivo has not been addressed to ...of L. amazonensis to ...
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Leishmania braziliensis and Leishmania amazonensis amastigote extracts differ in their enhancement effect on Leishmania infection when injected intradermally
... of Leishmania amazonensis amastigote extract (LaE) in BALB/c mice exacerbates the infection of these mice by Leishmania ...a Leishmania braziliensis amastigote extract (LbE) would exert the ...
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Imipramine alters the sterol profile in Leishmania amazonensis and increases its sensitivity to miconazole
... biosynthesis, Leishmania also uptakes a significant amount of exogenous cholesterol, mainly through the endocytosis of LDL particles ...in L. amazonensis increases the intake of cholesterol from the ...
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Intranasal vaccination with extracellular serine proteases of Leishmania amazonensis confers protective immunity to BALB/c mice against infection
... from L. ama- zonensis culture. Exogenous antigens from Leishmania major culture (SEAgs) have been evaluated as vaccine can- didates against ...from Leishmania amazonensis and we predicted the ...
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ANTILEISHMANIAL ACTIVITY OF LEAF EXTRACT FROM CALOPHYLLUM RIVULARE AGAINST LEISHMANIA AMAZONENSIS
... In the present study, we report for the first time the evaluation of leaves from C. rivulare against L. amazonensis. Table 1 shows the antileishmanial activity and cytotoxicity of evaluated products. The ...
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Low-Dose UVB Contributes to Host Resistance against Leishmania amazonensis Infection in Mice through Induction of Gamma Interferon and Tumor Necrosis Factor Alpha Cytokines
... for Leishmania disease ...against Leishmania infection (27, 43) and most likely acts in synergy with IFN-␥ to activate macro- phages to synthesize nitric oxide, which kills the intracellular parasites ...
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Transcriptional responses of Leishmania (Leishmania) amazonensis in the presence of trivalent sodium stibogluconate
... of Leishmania and other trypanosomatid spe- cies ...that L. amazonensis reduces the expression of some genes involved in virulence, inter- action and survival in macrophages that are not neces- sary ...
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Efficacy of intranasal LaAg vaccine against Leishmania amazonensis infection in partially resistant C57Bl/6 mice
... different Leishmania parasites is the priority to control leishman- iasis ...whole Leishmania amazonensis antigens, has been studied for several ...
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EVALUATION OF THE IMMUNOMODULATORY EFFECT OF PIPLARTINE AND ITS DERIVATIVE ON PERITONEAL MACROPHAGES OF SWISS MICE INFECTED WITH LEISHMANIA AMAZONENSIS
... peritoneal macrophages of mice infected with L. amazonensis, as well as with other species of Leishmania sp. which cause cutaneous leishmaniasis 10-32 . It is known that the interaction of ...
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Leishmania amazonensis infection impairs dendritic cell migration from the inflammatory site to the draining lymph node
... that Leishmania infection decreases the adhesion of inflammatory phagocytes to connective tissue by a mechanism dependent on the modulation of integrin ...of L. amazonensis infection on the ability ...
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Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis
... with Leishmania amazonensis, different co- cultures were ...for Leishmania major infection, where C57BL/6 peritoneal macrophages exposed to AD-MSCs through transwell plates and then infected did not ...
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A lupane triterpene isolated from Combretum leprosum Mart fruit extracts that interferes with the intracellular development of Leishmania (L ) amazonensis in vitro
... The 3β,6β,16β-trihydroxylup-20(29)-ene concentration adopted in this study was sufficient to reduce the rate of infected macrophages and the number of intracellular amastigotes from 24 h-post treatment onwards. The ef- ...
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Lipophosphoglycan polymorphisms do not affect Leishmania amazonensis development in the permissive vectors Lutzomyia migonei and Lutzomyia longipalpis
... Several studies have already described the differenti- ation of Le. amazonensis, Le. braziliensis and Le. infantum in New World sand fly species including Lu. longipalpis and Lu. migonei [12, 19, 20, 45]. Con- ...
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Extracellular matrix alterations in experimental Leishmania amazonensis infection in susceptible and resistant mice
... Leishmania is inoculated, by the bite of an infected sandfly, into the skin of the host, where the promastigotes are phagocyted by dermal macrophages. The dermal region comprises cells and abundant extracellular ...
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In vitro biological action of aqueous extract from roots of Physalis angulata against Leishmania (Leishmania) amazonensis
... (L.) amazonensis promastigotes (10 6 parasites/mL) in the logarithmic growth phase were inoculated in a 24- well plate containing RPMI medium supplemented with 10 % FBS with different concentrations of ...
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