Leishmania (Leishmania) amazonensis
Resistance of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensisto nitric oxide correlates with disease severity in Tegumentary Leishmaniasis
... Leishmaniasis is a parasitic disease caused by the Leishma- nia spp. protozoa, transmitted to the skin of a mammalian host during the bite of an infected female sand fly vector. Infections range in severity from ...
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In vitro activity of Morinda citrifolia Linn fruit juice against the axenic amastigote form of Leishmania amazonensis and its hydrogen peroxide induction capacity in BALB/c peritoneal macrophages
... like Leishmania inhibits oxidative burst-mediated mac- rophage apoptosis to protect its survival and replication niche, as one of the mechanisms for establishing infec- ...L. amazonensis population, ...
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ANTILEISHMANIAL ACTIVITY OF LEAF EXTRACT FROM CALOPHYLLUM RIVULARE AGAINST LEISHMANIA AMAZONENSIS
... In the present study, we report for the first time the evaluation of leaves from C. rivulare against L. amazonensis. Table 1 shows the antileishmanial activity and cytotoxicity of evaluated products. The CR-2 ...
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Lipophosphoglycan polymorphisms do not affect Leishmania amazonensis development in the permissive vectors Lutzomyia migonei and Lutzomyia longipalpis
... of Leishmania including ...Le. amazonensis was detected for the first time in a New World Leishmania ...World Leishmania species including Le. major [15], Le. tropica /Leishmania ...
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The use of kDNA minicircle subclass relative abundance to differentiate between Leishmania (L ) infantum and Leishmania (L ) amazonensis
... the Leishmania (Leish- mania) and Leishmania (Viannia) subgenera could be distinguished by exploiting kDNA variability through HRM analysis of qPCR-ML amplicons ...different Leishmania species were ...
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Low-Dose UVB Contributes to Host Resistance against Leishmania amazonensis Infection in Mice through Induction of Gamma Interferon and Tumor Necrosis Factor Alpha Cytokines
... for Leishmania disease ...against Leishmania infection (27, 43) and most likely acts in synergy with IFN-␥ to activate macro- phages to synthesize nitric oxide, which kills the intracellular parasites ...
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Intranasal vaccination with extracellular serine proteases of Leishmania amazonensis confers protective immunity to BALB/c mice against infection
... recombinant Leishmania vaccine formu- lated with the MPL-SE adjuvant have progressed to phase-II clinical trials against cutaneous and visceral leishmaniasis [3,4], no vaccine has been considered safe and/or ...
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Essential oils: in vitro activity against Leishmania amazonensis, cytotoxicity and chemical composition
... Background: The current chemotherapy for cutaneous leishmaniosis (CL) has a series of drug limitations such as toxic side effects, long duration, high costs and drug resistance, which requires the development of new ...
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Impact of reactive oxygen species (ROS) on the control of parasite loads and inflammation in Leishmania amazonensis infection
... genus Leishmania: some parasites are susceptible to their action, while others seem to be ...L. amazonensis infection in vivo has not been addressed to ...L. amazonensis to address the effect of ROS ...
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Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis
... cure Leishmania major infection ...of Leishmania amazonensis ...to Leishmania major infection [72, 73] and to Leishmania amazonensis infection ...in Leishmania major ...
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Extracellular matrix alterations in experimental Leishmania amazonensis infection in susceptible and resistant mice
... Leishmania is inoculated, by the bite of an infected sandfly, into the skin of the host, where the promastigotes are phagocyted by dermal macrophages. The dermal region comprises cells and abundant extracellular ...
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Imipramine alters the sterol profile in Leishmania amazonensis and increases its sensitivity to miconazole
... biosynthesis, Leishmania also uptakes a significant amount of exogenous cholesterol, mainly through the endocytosis of LDL particles ...L. amazonensis increases the intake of cholesterol from the culture ...
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Transcriptional responses of Leishmania (Leishmania) amazonensis in the presence of trivalent sodium stibogluconate
... of Leishmania and other trypanosomatid spe- cies ...L. amazonensis reduces the expression of some genes involved in virulence, inter- action and survival in macrophages that are not neces- sary for survival ...
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IL 32γ promotes the healing of murine cutaneous lesions caused by Leishmania braziliensis infection in contrast to Leishmania amazonensis
... Biopsy fragments were obtained from cutaneous lesions to identify Leishmania species by polymerase chain re- action (PCR) as previously described [8], confirming all samples positive for L. amazonensis. ...
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Leishmania braziliensis and Leishmania amazonensis amastigote extracts differ in their enhancement effect on Leishmania infection when injected intradermally
... of Leishmania amazonensis amastigote extract (LaE) in BALB/c mice exacerbates the infection of these mice by Leishmania ...a Leishmania braziliensis amastigote extract (LbE) would exert the ...
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In vitro biological action of aqueous extract from roots of Physalis angulata against Leishmania (Leishmania) amazonensis
... (L.) amazonensis promastigotes (10 6 parasites/mL) in the logarithmic growth phase were inoculated in a 24- well plate containing RPMI medium supplemented with 10 % FBS with different concentrations of AEPa, and ...
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Polymorphism specific PCR enhances the diagnostic performance of American tegumentary leishmaniasis and allows the rapid identification of Leishmania species from Argentina
... that Leishmania (Vian- nia) braziliensis was the prevalent species causing three different clinical forms of ATL: cutaneous (CL), mucocu- taneous (MCL), and recurrent cutaneous leishmaniasis in Salta ...province. ...
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Moroccan strains of Leishmania major and Leishmania tropica differentially impact on nitric oxide production by macrophages
... that Leishmania species block apoptosis of their host cells, thus extending their viability [5, ...L. amazonensis-infection of C57BL/6 mice is con- trolled via NO and reactive oxygen species (ROS) pro- ...
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TLR9/MyD88/TRIF signaling activates host immune inhibitory CD200 in Leishmania infection
... L. amazonensis is dependent on the release of mVEs containing specific DNA sequences inside the macrophage parasitophorous ...L. amazonensis amastigotes reside within acidic parasito- phorous vacuoles with ...
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Identification of Leishmania tropica and Leishmania aethiopica by DNA sequencing and the detection of Leishmania RNA Virus
... of Leishmania infections such as diffuse cutaneous leishmaniasis also occur in other parts of the world other than South America, such as Ethiopia (Zangger at ...as Leishmania panamensis, Leishmania ...
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