Leptin Resistance
<p>Leptin resistance: underlying mechanisms and diagnosis</p>
... of leptin resistance based on the assumption that leptin itself regulates the activity of its own ...of leptin, leptin receptors, and the regulation of food intake, as well as body ...
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Agrarian diet and diseases of affluence – Do evolutionary novel dietary lectins cause leptin resistance?
... [39]. Leptin also affects the growth of blood vessels and bone; the immune system; glucose- and fat metabolism and the reproductive system ...[32,40]. Leptin administered peripherally in animal models such ...
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Leptin resistance contributes to obesity and hypertension in mouse models of Bardet Biedl syndrome
... hormone leptin. The effect of exogenous leptin on body weight and food intake was attenuated in BBS mice, which suggests that leptin resistance may contribute to ...obesity, leptin ...
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Two defects contribute to hypothalamic leptin resistance in mice with diet induced obesity
... increased leptin levels (Fig- ure 2c). The ability of leptin to induce STAT3 signaling was first studied after 4 weeks on the ...mouse leptin by the ip ...peripheral leptin treatment induced ...
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Does elevated bilirubin aid weight control by preventing development of hypothalamic leptin resistance?
... of leptin-responsive neurons—can be reversed by elevation of bilirubin (or administration of PhyCB) in patients who have already developed obesity with leptin resistance remains to be ...
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Attenuation of Zn-induced hyperleptinemia/leptin resistance in Wistar rat after feeding modified poultry egg
... The implication of these reports has a direct relationship of excessive Zn in diet to the obesity and obesity related diseases, the incidence of which are increasing consistently during the past two decades due to its ...
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Hepatic CB1 receptor is required for development of diet induced steatosis, dyslipidemia, and insulin and leptin resistance in mice
... lipid profile as well as leptin and insulin levels. Obesity induced by high-fat diets in mice is associated with changes char- acteristic of the metabolic syndrome, i.e., altered plasma lipid profile as well as ...
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Beta-Carotene: Positive Effect on Oxidative Stress, Lipid Peroxidation, Insulin and Leptin Resistance Induced by Dietary Fat Consumption
... puncture, Leptin and insulin hormonal assay and oxidative enzyme markers were evaluated using the respective standard ...of leptin, insulin and Malondialdehyde (MDA)were higher for group B when compared to ...
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KBH 1, an herbal composition, improves hepatic steatosis and leptin resistance in high fat diet induced obese rats
... through leptin resistance as the pathological status in clinics ...[2]. Leptin, an adipose-derived hormone, is known to act on the hypothalamus of the brain to reduce food in- take and increase ...
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Role of leptin resistance in the development of obesity in older patients
... obesity, resistance to hormones such as insulin and leptin can be ...observed. Leptin is a circulating hormone/cytokine with central and peripheral effects that is released mainly by subcutaneous ...
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Resistance to adenovirally induced hyperleptinemia in rats Comparison of ventromedial hypothalamic lesions and mutated leptin receptors
... of leptin, the fat content of their pancreatic islets ranges from 10 to 100 times normal ...of leptin, an increase in fat content and the appearance of diabetic ab- normalities should have been ...to ...
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Diet induced obese mice develop peripheral, but not central, resistance to leptin
... in leptin-deficient ob/ob mice; its effects in obese humans, who have high circulating leptin levels, remain to be ...produces resistance to peripheral and/or central leptin ...Serum ...
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The long road to leptin
... of leptin for the treat- ment of obesity has been augmented by combining it with other agents that cause weight loss, in particular, short- term signals including intestinal peptides that modulate meal ...of ...
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THE UNFOLDING TALE OF LEPTIN
... to leptin deficiency, leptin resistance is hypothesized to occur at various levels in the leptin ...of leptin antibodies, or (b) increased leptin binding proteins, or (c) ...
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Effects of a single session of concurrent exercise on leptin levels and insulin resistance index in sedentary males
... and resistance to insulin. In the obese mice (zucher) with leptin receptors disorder, hyperlipidemia and -cell disorder, it was noticed that leptin injection in the -cell isolated from this animal ...
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ROLE OF LEPTIN IN OBESITY .......
... to leptin resulting in a lack of satiety and appetite sup- ...more leptin into the circulation in an attempt to send the message to the brain that fat stores are adequate, and appetite needs to be reined ...
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Intermittent Hypoxia Affects Leptin and Leptin Receptor Signaling in the Rat Carotid Body
... of leptin were made immediately after the exposure of the animals to IH or the normoxic ...later leptin analysis. Plasma was aliquoted and leptin was measured using a TiterZyme enzyme immunometric ...
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Maternal serum adiponectin, leptin and adiponectin-leptin ratio as possible biomarkers of preeclampsia
... between leptin and blood pressure in the normal pregnant women, and the increase in strength of this positive correlation in preeclampsia suggests that the pathophysiological progression of preeclampsia may ...
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Association of serum leptin and adiponectin with anthropomorphic indices of obesity, blood lipids and insulin resistance in a Sub-Saharan African population
... We found that plasma adiponectin concentrations are positively correlated to age, and negatively related with BMI, WC, BF%, WHR, triglycerides, insulin levels, and HOMA-IR. In contrast, leptin plasma levels ...
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Serum concentrations of cortisol, interleukin 6, leptin and adiponectin predict stress induced insulin resistance in acute inflammatory reactions
... insulin resistance in humans ...insulin resistance [18,19], while antibody-neutralisation exper- iments of IL6 were found to do the opposite ...insulin resistance in humans [22] and was even ...
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