Leukocyte telomere length
Shortened leukocyte telomere length in type 2 diabetes mellitus: genetic polymorphisms in mitochondrial uncoupling proteins and telomeric pathways
... shortened leukocyte telomere length (LTL) as the result of a number of possible causes, including polymorphisms in mitochondrial uncoupling proteins (UCPs) leading to oxida- tive stress, ...
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Leukocyte Telomere Length in Newborns: Implications for the Role of Telomeres in Human Disease
... BACKGROUND AND OBJECTIVE: In adults, leukocyte telomere length (LTL) is variable, familial, and longer in women and in offspring conceived by older fathers. Although short LTL is associated with ...
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Circulating leukocyte telomere length is highly heritable among families of Arab descent
... profile. Leukocyte telomere length was determined using quantitative real time ...Results: Telomere length was highly heritable as assessed by a parent-offspring regression [h2 = ...
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Obesity and inflammation markers in relation to leukocyte telomere length in a cross-sectional study of persons with Barrett’s esophagus
... affect telomere length by promoting inflammation; studies have impli- cated adipokines in the development of insulin resist- ance, accelerated cell senescence and ageing ...to telomere shortening by ...
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Leukocyte telomere length in paediatric critical illness: effect of early parenteral nutrition
... in leukocyte telomere length from admission to the last PICU day was first assessed in a univariate way for the total number of patients for whom leukocyte telomere length was ...
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Leukocyte telomere length and depression, anxiety and stress and adjustment disorders in primary health care patients
... that telomere length is significantly shorter in patients with depression or mood disorders as compared to controls [4, 12, 13, ...between telomere length and severity of depression have also ...
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Genetic Variation of hTERT, Leukocyte Telomere Length and the Risk of Breast Cancer: A Case Control Study in Egyptian Females
... Leukocyte telomere length measurement was carried out according to the quantit- ative PCR method reported previously by Gil et ...the telomere PCR. The primer sequences for both ...
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Association among dispositional mindfulness, self-compassion, and leukocyte telomere length in Chinese adults
... Relative leukocyte telomere length (LTL) measurement Relative LTL was measured using the Cawthon method [32] as previously described by Yim et ...fixed-length telomere product in a ...
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Parental care influences leukocyte telomere length with gender specificity in parents and offsprings
... and leukocyte telomere length in both males and females, ...shorter telomere length ...and telomere length which covers both lower and higher ends of parental ...against ...
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Leukocyte telomere length and serum polyunsaturated fatty acids, dietary habits, cardiovascular risk factors and features of myocardial infarction in elderly patients
... their length is shortened with each cell division. The telomere loss over time is age-dependent in humans [7], ranging 30– 200 base pairs per cell cycle ...certain length, the cells cease to divide, ...
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Leukocyte telomere length and mortality risk in patients with type 2 diabetes
... Leukocyte telomere length (LTL) shortening is found in a number of age-related diseases, including type 2 diabetes (T2DM). In this study its possible association with mortality was analyzed in a ...
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Mendelian randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers
... for telomere maintenance offers some protection against genomic instability due to oxidative stress, declining regenerative capacity and immune function(7, 65, ...
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Cognitive performance and leukocyte telomere length in two narrow age-range cohorts: a population study
... Whether telomere length at Wave 2 was associated with decline in cogni- tive performance from Wave 1 to Wave 2 was underta- ken by assessing cognitive performance at Wave 2 residualised for Wave 1 ...
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Smoking, second-hand smoke exposure and smoking cessation in relation to leukocyte telomere length and mortality
... and telomere length has been reported in a study among older adults (50–75 years) in Germany ...[26]. Telomere elongation may also indicate reactivation of telomerase pathways as reported in some ...
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Mitochondrial DNA copy number variation, leukocyte telomere length, and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study
... on telomere length for 570 controls and 533 cases, measurements on mtDNA copy number on 548 controls and 522 cases, and measurements on mtDNA deletions on 539 controls and 519 ...
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Association of peripheral leukocyte telomere length and its variation with pancreatic cancer and colorectal cancer risk in Chinese population
... In this study, we conducted a nested case–control study in a Chinese population and evaluated the relationships between relative LTL, TLV and risk of pancreatic cancer and CRC. Our results showed that either short or ...
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Leukocyte telomere length and diabetes status, duration, and control: the 1999–2002 National Health and Nutrition Examination Survey
... ening. Telomere length may vary among cells in the same tissue and among chromosomes in the same cell, but a previous study showed telomere length from different tis- sues within the same ...
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An overview of methods to address distinct research questions on environmental mixtures: an application to persistent organic pollutants and leukocyte telomere length
... research questions concerning associations with a specific health outcome and can help identify potentially toxic agents in a mixture, synergistic activities among a mix- ture’s componen[r] ...
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Association between prediagnostic leukocyte telomere length and breast cancer risk: the Singapore Chinese Health Study
... Two sets of Cox regression models were employed in assessing the association between telomere length and breast cancer risk. The first model included age (years) at blood draw and dialect group (Hokkien or ...
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Is Leukocyte Telomere Length Related with Lung Cancer Risk?: A Meta-Analysis
... the telomere length shortening and the increased risk of lung cancer; however, there was no significant correlation was found from the prospective studies ...and telomere length and the risk ...
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