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ligamentum flavum

Phenotypic Characterization of Ligamentum Flavum Cells from Patients with Ossification of Ligamentum Flavum

Phenotypic Characterization of Ligamentum Flavum Cells from Patients with Ossification of Ligamentum Flavum

... of ligamentum flavum cells from patients with ossification of the ligamentum flavum ...Methods: Ligamentum flavum tissues were harvested from OLF and non-OLF patients during ...

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A cervical ligamentum flavum cyst in an 82 year old woman presenting with spinal cord compression: a case report and review of the literature

A cervical ligamentum flavum cyst in an 82 year old woman presenting with spinal cord compression: a case report and review of the literature

... lesions. Ligamentum flavum cysts appear as well-demarcated, isointense lesions on T1- weighted images, while they are usually hyperintense on T2-weighted images ...tum flavum cysts ...

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Thoracic myelopathy caused by ossification of ligamentum flavum of which fluorosis as an etiology factor

Thoracic myelopathy caused by ossification of ligamentum flavum of which fluorosis as an etiology factor

... Fluoride is an important element for bone mineralization. It causes an increase in bone mass by stimulation of the osteogenetic process [1]. However, over intake of fluoride may cause fluoride intoxication, so-called ...

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Ossification process involving the human thoracic ligamentum flavum: role of transcription factors

Ossification process involving the human thoracic ligamentum flavum: role of transcription factors

... Real-time RT-PCR was used for semiquantitative ana- lysis of the relative mRNA expression levels of tran- scriptional factors (repeated 3 times for each sample), by using cultured ligamentum flavum cells ...

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The expression of P16 and S100 associated with elastin degradation and fibrosis of the Ligamentum Flavum hypertrophy

The expression of P16 and S100 associated with elastin degradation and fibrosis of the Ligamentum Flavum hypertrophy

... Background: One of the characteristics of lumbar spinal stenosis (LSS) is elastin degradation and fibrosis in the ligamentum flavum (LF). However, the biochemical factors that cause these histologic changes ...

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Simultaneous Diffuse Idiopathic Hyperostosis, Ossification of the Posterior Longitudinal Ligament and Ligamentum Flavum

Simultaneous Diffuse Idiopathic Hyperostosis, Ossification of the Posterior Longitudinal Ligament and Ligamentum Flavum

... Background and Importance: A 60-year-old diabetic man with simultaneous diffuse idiopathic hyperostosis, massive ossification of the posterior longitudinal ligament and cervical and higher part of thoracic ...

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Original Article Increased expression of WISP-1 (CCN4) contributes to fibrosis in the hypertrophied lumber ligamentum flavum

Original Article Increased expression of WISP-1 (CCN4) contributes to fibrosis in the hypertrophied lumber ligamentum flavum

... Abstract: The molecular mechanism of the tissue fibrosis of ligamentum flavum (LF) in patients with lumbar spinal canal stenosis (LSCS) has not been ascertained. Wnt-induced secreted protein-1 (WISP-1) is a ...

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MiR-490-3p inhibits osteogenic differentiation in thoracic ligamentum flavum cells by targeting FOXO1

MiR-490-3p inhibits osteogenic differentiation in thoracic ligamentum flavum cells by targeting FOXO1

... that miR-490-3p could directly target the 3’-UTR of FOXO1 mRNA and is identified as a regulator of FOXO1 in thoracic ligamentum flavum cells. This finding led us to further explore the effect of miR-490-3p ...

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Multilevel thoracic ossification of ligamentum flavum coexisted with/without lumbar spinal stenosis: staged surgical strategy and clinical outcomes

Multilevel thoracic ossification of ligamentum flavum coexisted with/without lumbar spinal stenosis: staged surgical strategy and clinical outcomes

... Surgical management of multilevel thoracic ossifica- tion of ligamentum flavum, especially discontinuous multi-segmental lesions, can be a complex undertaking involving considerable risk. Two surgical ...

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Comparison of Histological Changes in the Ligamentum Flavum from Spinal Canal Stenosis Patients with and without Diabetes Mellitus

Comparison of Histological Changes in the Ligamentum Flavum from Spinal Canal Stenosis Patients with and without Diabetes Mellitus

... Materials and Methods: In this case control study, during 9 months, twenty-nine patients, who were candidate for decompressive laminectomy because of ligamentum flavum hypertrophy, were studied. They were ...

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CT-Guided Percutaneous Lumbar Ligamentum Flavum Release by Needle Knife for Treatment of Lumbar Spinal Stenosis: A Case Report and Literature Review

<p>CT-Guided Percutaneous Lumbar Ligamentum Flavum Release by Needle Knife for Treatment of Lumbar Spinal Stenosis: A Case Report and Literature Review</p>

... the ligamentum flavum also forms part of the posterior edge of the intervertebral foramen, under hypertrophic conditions it causes a decrease in the width of the interver- tebral foramen, which results in ...

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Ligamentum flavum cyst in the lumbar spine: a case report and review of the literature

Ligamentum flavum cyst in the lumbar spine: a case report and review of the literature

... the ligamentum flavum have myxoid degener- ation and arise from or are partially embedded in the inner surface of this ligament, and in contrast to juxta-articular cysts, are not related to the facet joint ...

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Congenital lumbar spinal stenosis with ossification of the ligamentum flavum in achondroplasia: a case report

Congenital lumbar spinal stenosis with ossification of the ligamentum flavum in achondroplasia: a case report

... Concerning treatment after diagnosis, it is important to decide the optimal timing of surgical intervention for achondroplastic patients with spinal stenosis. In the present case, decompressive wide laminectomy and re- ...

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Original Article Application of piezosurgery to treat thoracic myelopathy caused by ossification of the ligamentum flavum

Original Article Application of piezosurgery to treat thoracic myelopathy caused by ossification of the ligamentum flavum

... Abstract: Objective: Piezosurgery is based on microvibrations generated by the piezoelectrical effect, which results in selective bone cutting with preservation of adjacent soft tissue. We aimed to study the ...

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Dose dependent regulation of cell proliferation and collagen degradation by estradiol on ligamentum flavum

Dose dependent regulation of cell proliferation and collagen degradation by estradiol on ligamentum flavum

... Surgical specimens of ligamentum flavum were obtained from 14 patients (8 female and 6 male, mean age was 58.8, range from 45 to 78 years) undergoing spinal surgery under the diagnosis of lumbar spinal ...

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Assessment of ligamentum flavum thickness correlation with demographic variables and disc degeneration in Erbil governorate population sample

Assessment of ligamentum flavum thickness correlation with demographic variables and disc degeneration in Erbil governorate population sample

... The LF is an important anatomical structure, which might cause lower back or leg pain. Therefore, the thickness of the LF should be measured and evaluated carefully in the case of spinal stenosis 7 . This study aims to ...

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Predictive factors for surgical outcome of ossification of ligamentum flavum of spine in a series of 31 cases

Predictive factors for surgical outcome of ossification of ligamentum flavum of spine in a series of 31 cases

... This is to certify that Dr. JOHN CHRISTOPHER. S., who is appearing for M.Ch. degree examination in Neurosurgery in August 2010 has prepared this dissertation entitled “PREDICTIVE FACTORS FOR SURGICAL OUTCOME OF ...

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Subsection Laminectomy with Pedicle Screw Fixation to Treat Thoracic Ossification of Ligamentum Flavum: A Comparative Analysis with Lamina Osteotomy and the Replantation Technique

<p>Subsection Laminectomy with Pedicle Screw Fixation to Treat Thoracic Ossification of Ligamentum Flavum: A Comparative Analysis with Lamina Osteotomy and the Replantation Technique</p>

... the ligamentum fl avum at the zygapophysial joints and gradually forms a nodular ossi fi ca- tion process that projects into the spinal canal and extends to the ligamentum fl avum at the central portion of the ...

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Original Article Transforming growth factor β/Smad pathway participates in lumbar ligamentum flavum hypertrophy

Original Article Transforming growth factor β/Smad pathway participates in lumbar ligamentum flavum hypertrophy

... Notably, increased p-Smad 2/3 levels were cor- related with increased expression of type I col- lagen. These findings suggest that collagen deposition in the ligamentum flavum is depen- dent on TGFβ/Smad pathway ...

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Original Article Expression and role of osteopontin in ossification of ligmentum flavum

Original Article Expression and role of osteopontin in ossification of ligmentum flavum

... of ligamentum flavum (OLF) is an ectopic ossification disease that may lead to spinal cord compression, but identifying patho- genesis still needs further ...of ligamentum flavum progresses by ...

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