Lipoprotein lipase
A missense mutation at codon 188 of the human lipoprotein lipase gene is a frequent cause of lipoprotein lipase deficiency in persons of different ancestries
... Lipoprotein lipase (LPL) plays a crucial role in the regulation of lipoprotein metabolism by hydrolysing the core triglycerides of circulating chylomicrons and ...
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High density lipoprotein2 Relationship of the plasma levels of this lipoprotein species to its composition, to the magnitude of postprandial lipemia, and to the activities of lipoprotein lipase and hepatic lipase
... Lipoprotein lipase (LPL) activity in postheparin plasma of 38 normolipidemic volunteers was related to the magnitude of postprandial lipemia after a fat meal, to triglyceride content of high density ...
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The novel compound NO 1886 increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol, and long term administration inhibits atherogenesis in the coronary arteries of rats with experimental atherosclerosis
... We have discovered a novel compound, NO-1886, which possesses a powerful lipoprotein lipase (LPL) activity-increasing action. Administration of NO-1886 increased LPL activity in the postheparin plasma, ...
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Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormones sensitive lipase in human subcutaneous abdominal adipocytes
... between lipoprotein lipase activity and plasma sex steroid levels in obese ...tissue lipoprotein lipase - Possible mechanism of body fat ...
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Lipoprotein metabolism during acute inhibition of lipoprotein lipase in the cynomolgus monkey
... of lipoprotein lipase (LPL) in the catabolism of nascent and circulating very low density lipoproteins (VLDL) and in the conversion of VLDL to low density lipoproteins (LDL), studies were performed in which ...
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Effects of insulin and exercise on muscle lipoprotein lipase activity in man and its relation to insulin action
... The effects of exercise and a physiological increase in plasma insulin concentration on muscle lipoprotein lipase activity (mLPLA), leg exchange of glucose, and serum lipoprotein levels were ...
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Effect of heparin induced lipolysis on the distribution of apolipoprotein e among lipoprotein subclasses Studies with patients deficient in hepatic triglyceride lipase and lipoprotein lipase
... hepatic lipase or of lipoprotein lipase and compared them with normal ...triglyceride lipase deficiency (n = 2) differ markedly from normal in that fraction II is the dominant apo E-containing ...
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Role of adipocyte-derived lipoprotein lipase in adipocyte hypertrophy
... The availability of VLDL-derived fatty acids for energy needs and adipocyte storage is dependent upon hydrolytic activity of lipoprotein lipase (LPL) [3-6], and to a lesser extent, endothelial lipase ...
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Lipoprotein particle distribution and skeletal muscle lipoprotein lipase activity after acute exercise
... The NMRS technique provides new insights about the concentration of lipoprotein particles with more clarity than possible from biochemical methods. Although there are far more apoB-100 containing VLDL particles in ...
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Schickel, Ralph (2005): Identification of the nucleotide sequence of the lipoprotein lipase gene as well as its role in the development of hyperlipidemia and pancreatitis in the Miniature Schnauzer. Dissertation, LMU München: Tierärztliche Fakultät
... Based on these findings we were evaluating a possible role of the lipoprotein lipase gene in the development of pancreatitis and hyperlipidemia in the Miniature Schnauzer. First, we identified the genetic ...
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Bovine milk lipoprotein lipase transfers tocopherol to human fibroblasts during triglyceride hydrolysis in vitro
... Lipoprotein lipase appears to function as the mechanism by which dietary vitamin E (tocopherol) is transferred from chylomicrons to ...with lipoprotein lipase deficiency, more than 85% of both ...
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Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase–deficient mouse adipose tissue
... Lipoprotein lipase (LPL) is responsible for the generation of fatty acids from circulating triglyceride-rich (TG-rich) lipoproteins. The enzyme is predominantly found in adipose tissue (AT) and muscle, ...
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The regulation of adipose tissue and muscle lipoprotein lipase in runners by detraining
... To study the mechanism of lipoprotein lipase (LPL) regulation by exercise, we recruited 16 healthy athletes to undergo a 2-wk period of detraining. Fasting fat and muscle biopsies were performed both before ...
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Regulation of lipoprotein lipase immunoreactive mass in isolated human adipocytes
... Previous studies of human adipose tissue lipoprotein lipase (LPL) have focused on enzyme catalytic activity, and have not measured the LPL protein directly. To study the regulation of the LPL protein, an ...
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Regulation of lipoprotein lipase in primary cultures of isolated human adipocytes
... To study the regulation of adipose tissue lipoprotein lipase (LPL) in human adipocytes, omental adipose tissue was obtained from healthy subjects and digested in collagenase. The isolated adipocytes thus ...
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Increase of adipose tissue lipoprotein lipase activity with weight loss
... tissue lipoprotein lipase activity per fat cell when compared with lean control ...of lipoprotein triglyceride in adipose tissue, has been shown to be further elevated in a group of previously obese ...
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The effect of estrogen on the lipoprotein lipase activity of rat adipose tissue
... tissue lipoprotein lipase activity from ...tissue lipoprotein lipase activity from ...tissue lipoprotein lipase activity: 17beta-estradiol ...decreased lipoprotein ...
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THE REMOVAL OF LIPOPROTEIN LIPASE FROM THE BLOOD BY THE NORMAL AND DISEASED LIVER
... HEPATIC REMOVAL OF LIPOPROTEIN LIPASE IN Two DOGS BEFORE AND AFTER DEVELOPMENT OF AcuTE HEPATIC NECROSIS The peripheral vein-hepatic vein differences for optical density change and glyce[r] ...
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KINETIC STUDIES ON METABOLISM OF LIPOPROTEIN LIPASE
... Coefficient and exponential constants of lipoprotein lipase LPL activity curve in human subjects, dogs, and rabbits injected with heparin, 0.1 mg per kg of body weight K*.. Mean Acute he[r] ...
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Lipoprotein lipase levels in patients with Coronary Artery Disease with Type 2 Diabetes Mellitus
... density lipoprotein cholesterol (HDL-C), both risk factors for the development of coronary artery disease ...the Lipoprotein lipase levels in patients with Coronary Artery Disease and in patients ...
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