live attenuated influenza vaccine
Live Attenuated Influenza Vaccine: Will the Phoenix Rise Again?
... The live attenuated influenza vaccine (LAIV) (FluMist) has undergone a roller coaster journey since its licensure in 2003 for eligible individuals 5 to 49 years of age and subsequent expansion ...
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Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children in The Gambia : an open-label, observational, phase 4 study
... of vaccine strain shedding at day 2 after LAIV at a given baseline serum HAI titre to each matched ...to vaccine haemagglutinin-matched and neuraminidase-matched influenza ...(G) vaccine ...
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Acceptability of intranasal live attenuated influenza vaccine; influenza knowledge and vaccine intent in The Gambia
... Influenza vaccine intent was assessed by asking participants if they would accept an influenza vaccine if it was freely available for themselves during pregnancy or for their children ...high ...
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Live Attenuated Influenza Vaccine Enhances Colonization of Streptococcus pneumoniae and Staphylococcus aureus in Mice
... WT influenza virus infection ...following influenza virus-pneumococcal coinfections of human middle ear epithelial cells ...seasonal influenza A viruses ...WT influenza virus within the URT ...
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Comparisons of the Humoral and Cellular Immune Responses Induced by Live Attenuated Influenza Vaccine and Inactivated Influenza Vaccine in Adults
... Both live attenuated influenza vaccines (LAIV) and inactivated influenza vaccines (IIV) induce protective immunity against ...increased vaccine-induced T cell and/or sIgA ...of vaccine-induced ...
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Reversion of Cold-Adapted Live Attenuated Influenza Vaccine into a Pathogenic Virus
... Although under current recommendations infants and immuno- compromised individuals should not take the vaccine, it may be administered to immunocompromised individuals who have not yet been diagnosed. In such an ...
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Interaction between the nasal microbiota and S pneumoniae in the context of live attenuated influenza vaccine
... between live-attenuated in fl uenza vaccine (LAIV), successive pneumococcal challenge, and the healthy adult nasal microbiota and mucosal immunity using an experimental human challenge ...
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HAI and NAI titer correlates of inactivated and live attenuated influenza vaccine efficacy
... future vaccine development efforts may consider prioritizing post-vaccination titer endpoints as criteria for screening and advancement of candidate vaccines, as better correlates of VE than fold- rise in ...the ...
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Interaction between the nasal microbiota and S pneumoniae in the context of live attenuated influenza vaccine
... (Supplementary Table 9). Initially, a multiplex PCR was carried out to detect parainfluenza virus 1 and 3, parainfluenza virus 2 and 4 or human coronavirus OC43, NL63, and 229E. If positive, a monoplex species-specific ...
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Development of a Mouse-Adapted Live Attenuated Influenza Virus That Permits In Vivo Analysis of Enhancements to the Safety of Live Attenuated Influenza Virus Vaccine
... 22. Miller MS, Gardner TJ, Krammer F, Aguado LC, Tortorella D, Basler CF, Palese P. 2013. Neutralizing antibodies against previously encoun- tered influenza virus strains increase over time: a longitudinal ...
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A Live Attenuated Equine H3N8 Influenza Vaccine Is Highly Immunogenic and Efficacious in Mice and Ferrets
... Equine influenza viruses (EIV) are responsible for rapidly spreading outbreaks of respiratory disease in ...a live attenuated candidate vaccine by re- verse genetics with the hemagglutinin and ...
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Evaluation of Live Attenuated Influenza A Virus H6 Vaccines in Mice and Ferrets
... Avian influenza A virus A/teal/HK/W312/97 (H6N1) possesses seven gene segments that are highly homol- ogous to those of highly pathogenic human influenza H5N1 viruses, suggesting that a W312-like H6N1 virus ...
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Temperature-Sensitive Live-Attenuated Canine Influenza Virus H3N8 Vaccine
... H3N8 LACIV is attenuated in canine tracheal explants compared to H3N8 WT CIV. To compare LACIV and WT H3N8 CIV pathogenicity and replication efficiency at the site of infection within dogs (Fig. 7), we inoculated ...
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Influenza B Virus NS1-Truncated Mutants: Live-Attenuated Vaccine Approach
... limiting influenza B virus vaccine studies. Only mouse- adapted influenza B viruses result in severe symptoms, such as weight loss and death, in infected ...current influenza B viruses are not ...
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Patterns of Illness in the Highly Febrile Young Child: Epidemiologic, Clinical, and Laboratory Correlates
... With the exception of a small group partic- ipating in live, attenuated influenza trials in which protective efficacy of the vaccine was demon- strated,8 the immunizing agents studied we[r] ...
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The Receptor Binding Specificity of the Live Attenuated Influenza H2 and H6 Vaccine Viruses Contributes to Vaccine Immunogenicity and Protection in Ferrets
... for influenza pandemics that may be caused by the H2 and H6 subtype influenza viruses, live attenuated influenza virus (LAIV) H2 and H6 vaccines are being developed and ...H6 ...
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Assessment of Route of Administration and Dose Escalation for an Adenovirus-Based Influenza A Virus (H5N1) Vaccine in Chickens
... recombinant vaccine technologies for use in poultry, such as the reverse-genetics-produced live attenuated influenza A vi- rus vaccine (18, 25, 33) and a Newcastle disease virus (NDV)- ...
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Attenuation of influenza A virus by insertion of a foreign epitope into the neuraminidase.
... 4647 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest As the initial step in generating a live attenuated influenza A vaccine, we attempted to substitute an unrelated ami[r] ...
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Live Attenuated and Inactivated Influenza Vaccine Effectiveness
... of influenza infection among those aged 9 to 17 ...of influenza A/H1N1pdm09 infection compared with IIV recipients (OR = ...of influenza A/H3N2 infection compared with IIV recipients (OR = ...of ...
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Seasonal Effectiveness of Live Attenuated and Inactivated Influenza Vaccine
... or influenza B virus infections over several ...in influenza positivity in the 2 vaccine ...2003–2004 influenza seasons demonstrated superior efficacy of trivalent LAIV over trivalent IIV ...
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