liver metastasis
Surgical treatment of recurrent urachal carcinoma with liver metastasis: a case report and literature review
... Background: Urachal carcinoma is a rare malignancy with poor prognosis due to late presentation of the disease and its aggressiveness. Surgery remains the mainstay of therapy even in cases of disease recurrence. To the ...
6
Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis
... Using reporter assays and chromatin immunoprecipitation approaches, it has recently been shown that the EGFR-MEK-ERK1/2 pathway can regulate the transcription of CLDN2 in A549 lung adenocarcinoma cells [28]. In these ...
12
Prognostic effect of liver metastasis in lung cancer patients with distant metastasis
... of metastasis and treatment ...to liver (61.9%). The incidence of liver metastasis in patients with lung cancer has been reported to be 37–51% in autopsy ...distant metastasis, of which ...
9
Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages
... MiR-18a, an important member of miR-17–92 family, has been shown various effects on different tumors. It was reported that miR-18a could act as a tumor suppressor. Our previous study published showed that miR- 18a ...
15
A case of long-term survival following hepatectomy for liver metastasis of Merkel cell carcinoma
... early metastasis to the lymph nodes, lung, skin, and central nervous system ...with liver metastasis of MCC rarely have a chance undergoing hepatectomy, and there are no reports of any long-term ...
6
Mechanisms involved in breast cancer liver metastasis
... initiate liver metastasis, of which C-X-C Chemokine Receptor type 4 (CXCR4) is the most ...the liver [30], indicating that the CXCL12/CXCR4 interaction might contribute to ...to-liver ...
10
Does Liver Resection Provide Long Term Survival Benefits for Breast Cancer Patients with Liver Metastasis? A Single Hospital Experience
... consider liver metastasis from malignant cancer as a sys- temic recurrence rather than a local recurrence, their therapeutic aim is only to im- prove the quality of life using conservative ...However, ...
5
Intrapancreatic bile duct metastasis from colon cancer after resection of liver metastasis with intrabiliary growth: a case report
... between liver metas- tasis with intrabiliary growth and intrahepatic cholangio- carcinoma, not only on the basis of preoperative imaging findings but also on the basis of histologic examination with ...
7
The paradigm of tumor shrinkage and rapid liver remnant hypertrophy for conversion of initially unresectable colorectal liver metastasis: a case report and literature review
... colorectal liver metastasis (CRLM) patients, hepatic resection is currently the sole cure offering the chance of long-term ...planned liver remnant hypertrophy are the two key strategies for ...
5
Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival
... Resected colorectal cancer and paired liver metastasis tis- sue specimens were sliced into 3.5-μm-thick sections and deparaffinized in five min. After blocking nonspecific binding with 10% bovine serum ...
7
APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis
... hepatic metastasis, we generated retrovirus- encoded shRNAs (Supplemental Figure 3) and cDNA expression constructs to stably knock down or overexpress these target ...and metastasis activity of L-1 cells (P ...
12
Molecularly annotation of mouse avatar models derived from patients with colorectal cancer liver metastasis
... As already described for other PDXs, histologic and molecular fidelity of the model to the original patient sample was conserved across multiple serial passages [3-5]. All of these are key advantages of these models with ...
16
Risk factors of liver metastasis from advanced pancreatic adenocarcinoma: a large multicenter cohort study
... synchronous metastasis rate in stage IV ...the liver metastases in advanced PDAC and its influencing ...chronous liver metastasis for stage IV ...develop liver metas- tases in stage IV ...
7
FAK is a Critical Regulator of Neuroblastoma Liver Metastasis
... the liver when compared to control (CC), and reintroducing GRP-R (GG) into cells rescued the inhibitory effect of GC ...on liver metastasis, the mean weight of spleen and liver in these mice ...
12
Overexpression of eIF4E in colorectal cancer patients is associated with liver metastasis
... Purpose: Liver metastasis is one of the leading causes of death in colorectal cancer (CRC) ...rectal liver metastasis (CLM) and identify the functional role of eIF4E in CRC ...
8
Gastric neuroendocrine neoplasm with late liver metastasis
... Gastric neuroendocrine neoplasms (GNENs) are classified into three types according to their aetiology. We present a clinical case of a female patient of 66 years and a well-differentiated (grade 2), type 3 GNEN with late ...
5
Laparoscopic liver resection as a safe and efficacious alternative to open resection for colorectal liver metastasis: a meta-analysis
... The results of this meta-anaysis should be interpreted with caution for several reasons. First, it should be noted that patients who underwent LLR were a highly selected population. In general, lesions located in the ...
8
ETIO-PATHOLOGICAL APPROACH OF CANCER IN AYURVEDIC AND CONTEMPORARY SCIENCE w.s.r to SROTAS INVOLVEMENT- A HYPOTHESIS .......
... Cancer is the second most common cause of death in the western world. It accounts for about 25% of death. Cancer is a disease of varied etiology and involves a wide variety of clinical syndromes. The basic underlying ...
5
Intrabiliary growth type of metastasis from colon cancer, 12 years after curative colectomy: a case report
... all liver metastases from colon cancer. Meanwhile, metastasis from other types of cancer ranges from ...identifying liver metastasis from cholangiocarcinoma [5, ...carcinoma metastasis, ...
9
Pattern of distant metastases in colorectal cancer: a SEER based study
... for liver, lung, bone and ...of liver metastasis than rectum cancer ...0.8%) metastasis than colon cancer, ...lung metastasis had a higher risk of bone ...brain metastasis ...
9