LNCaP cells
<p>Valproic Acid Addresses Neuroendocrine Differentiation of LNCaP Cells and Maintains Cell Survival</p>
... in LNCaP cells reduces cell proliferation, decreases the S phase and Cyclin A, and up-regulates the cyclin-dependent kinase inhibitors p21waf and ...in LNCaP prostate tumor cells, although it ...
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<p>Androgen upregulates the palmitoylation of eIF3L in human prostate LNCaP cells</p>
... We supplied three individual pairs of androgen-treated and non-treated LNCaP cells to screen the androgen-induced palmitoylated proteins. As a result, we identi fi ed 4351 unique peptides corresponding to ...
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Reciprocal regulation of PCGEM1 and miR-145promote proliferation of LNCaP prostate cancer cells
... line LNCaP but not in noncancerous prostate lines or androgen- receptor negative Pca lines ...in LNCaP cells promotes cell proliferation and a dramatic increase in colony formation, suggesting a role ...
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Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer
... in LNCaP cells (p-value < ...VCaP cells (Supplementary ...the LNCaP and VCaP neo-enhancers and found a remarkably high concordance in the significant gene sets (Supplementary ...blue). ...
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HMGB1 Promotes Prostate Cancer Development and Metastasis by Interacting with Brahma-Related Gene 1 and Activating the Akt Signaling Pathway
... Next, we sought to determine the role of HMGB1 in tumor invasion and metastasis. Results of migration and invasion in vitro assays showed that depleted HMGB1 suppressed cell migration and invasion of PC-3 and ...
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High intracellular Zn2+ ions modulate the VHR, ZAP-70 and ERK activities of LNCaP prostate cancer cells
... in LNCaP prostate cancer cells. LNCaP cells were used because they have been shown to exhibit the characteristics of the lateral prostate cells of the rat, which is homologous to the ...
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SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-Myc in prostate cancer
... cancer cells has been closely linked with epithelial-mesenchymal transition (EMT), which represents a series of phenotypic and behavioral changes in tumor cells, allowing their transition from indolent to ...
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Cell Cycle Arrest and Cytotoxic Effects of SAHA and RG7388 Mediated through p21WAF1/CIP1 and p27KIP1 in Cancer Cells
... cell cycle arrest effects of SAHA and RG7388 on using MCF-7 and LNCaP cells.. The cytotoxicity, cell 29.[r] ...
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Androgen receptor signaling is required for androgen-sensitive human prostate cancer cell proliferation and survival
... for LNCaP cell proliferation, GFP enriched LNCaP cells were collected through cell sorting at 24 hours following ...transfection. LNCaP cells transfected with the pSiCon-EGFP construct ...
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A re-evaluation of LINE-1 ORF2 expression in LNCaP prostate cancer cells
... cancer cells and found the highest rate of retrotransposition in LNCaP cells, followed by PC3 cells, 22Rv1 cells and very low levels in LAPC4 ...cancer cells were actively regu- ...
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IgG silencing induces apoptosis and suppresses proliferation, migration and invasion in LNCaP prostate cancer cells
... The Ig constant regions of human IgA, IgM, IgD, IgG3, IgG1 and IgE can be detected in many cancer cell lines via nested RT-PCR [7]. However, the individual functions of each Ig isotype in cancers are not clearly ...
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Luteolin inhibited proliferation and induced apoptosis of prostate cancer cells through miR-301
... heK-293T cells were cotransfected with mir-301-MiMic, psi-check2, WT-psi-check2, or MUT-psi-check2 of DeDD2 ...and lncaP cells transfected with mir-301-MiMic or mir-301-aMO were determined by qrT-Pcr ...
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Anti-tumor effects of a recombinant anti-prostate specific membrane antigen immunotoxin against prostate cancer cells
... Methods: We established a novel fusion gene, immunocasp-3, composed of NH2-terminal leader sequence fused with an anti-prostate-specific membrane antigen (PSMA) antibody (J591), the furin cleavage sequences of diphtheria ...
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Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability.
... treatment, LNCaP cells were washed twice in serum free RPMI and cultured for 72 hr in complete RPMI supplemented with 5% charcoal stripped serum instead of 10% ...FCS. LNCaP cells were ...
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Delivery of retinoic acid to LNCap human prostate cancer cells using solid lipid nanoparticles
... the LNCap prostate cancer cell line using the MTT assay. Cells were seeded in a 24 well flat-bottom plates at a cell density of 1 × 10 6 cells/well in 1 ml DMEM and incubated for 24 ...non-treated ...
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USP35 activated by miR let-7a inhibits cell proliferation and NF-κB activation through stabilization of ABIN-2
... cancer cells than that in non-malignant prostate epithelial cells ...cancer cells as well as in H1299 and A549 lung cancer cells compared with that in non-malignant breast epithelial ...
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TWIST1, A novel androgen-regulated gene, is a target for NKX3-1 in prostate cancer cells
... expression. LNCaP cells cultured in RPMI medium containing 10% FCS were transfected with 100 nM of siRNA against AR (AR) or a non-silencing control ...of LNCaP cells transfected with a ...
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Original Article MicroRNA-194-5p directly targets Rab23 and inhibits tumor progression in prostate cancer
... mal cells (Figure ...and LNCaP cells were among the most signifi- cantly downregulated cells regarding miR-194- 5p expression, we selected these two cell lines for further ...
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Original Article Differential expression of long non-coding RNAs in prostatic carcinoma cell line LNCaP after occurrence of androgen independent transformation
... CaP cells and LNCaP androgen-independent cells (LNCaP-AI cells) after the occurrence of androgen independent transformation using Human LncRNA Array containing 30,586 lncRNAs and 26,109 ...
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A dimerized urea-based inhibitor of the prostate-specific membrane antigen for 68Ga-PET imaging of prostate cancer
... on LNCaP and PC-3 cells indicated specific cell surface binding and internalization of [ 68 Ga]6 and [ 68 Ga]7 (Figure ...+ LNCaP cells was blocked in the presence of 2-PMPA, and both ...
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