lncRNA TUG1
LncRNA TUG1 was upregulated in osteoporosis and regulates the proliferation and apoptosis of osteoclasts
... (LncRNA) TUG1 plays critical roles in the development of human ...of lncRNA TUG1 in ankylosing ...of lncRNA TUG1 in plasma of 98 patients with osteoporosis and 60 healthy ...
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<p>LncRNA TUG1 Regulates Cell Viability and Death by Regulating miR-193a-5p/Rab10 Axis in Acute Myeloid Leukemia</p>
... of lncRNA TUG1 and Rab10 mRNA expression, total RNA was isolated using TRIzol LS Reagent (Ambion, Carsland, CA, USA), and then reversely transcribed into cDNA using PrimeScript RT Reagent kit (Takara Bio, ...
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Original Article lncRNA TUG1 promotes cell growth and epithelial-mesenchymal transition in human cervical cancer
... that lncRNA TUG1 play important roles in tumor ...high TUG1 expression was asso- ciated with chemotherapy resistance and poor prognosis in esophageal squamous cell carci- noma ...of TUG1 ...
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Original Article LncRNA TUG1 ameliorates diabetic nephropathy by inhibiting miR-21 to promote TIMP3-expression
... of lncRNA TUG1 on cell fibrosis, we overexpressed lncRNA TUG1 in high glucose-suppressed NRK-52E cells and down- regulated the expression of lncRNA TUG1 by small RNA interference ...
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Astragaloside IV/lncRNA-TUG1/TRAF5 signaling pathway participates in podocyte apoptosis of diabetic nephropathy rats
... and lncRNA-TUG1 overexpression decreased the TRAF5 protein level in 293 T cells (Figure ...between lncRNA- TUG1 knockdown and overexpression (Figure ...g/mL), lncRNA-TUG1 ...
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lncRNA TUG1 modulates proliferation, apoptosis, invasion, and angiogenesis via targeting miR-29b in trophoblast cells
... of lncRNA TUG1 and it was also reported to be one target of lncRNA TUG1 ...whether lncRNA TUG1 could modulate tropho- blast behaviors via sponging miR-29b remains ...and ...
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LncRNA TUG1 promoted KIAA1199 expression via miR-600 to accelerate cell metastasis and epithelial-mesenchymal transition in colorectal cancer
... that lncRNA TUG1 was upregulated in CRC cells, miR-600 was downregulated in CRC tissues, cell lines and CRC metastatic tissues, and low miR-600 expression predicted a poor clinical ...Moreover, TUG1 ...
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<p>lncRNA TUG1 Promotes Cell Proliferation, Migration, and Invasion in Hepatocellular Carcinoma via Regulating miR-29c-3p/<em>COL1A1</em> Axis</p>
... such as DBH-AS1, 5 MCM3AP-AS1 6 and CARL. 7 LncRNAs may act as competitive endogenous RNA (CeRNA) through sponging miRNAs, thus regulating miRNA expression in cells. 8 MiRNAs are an abundant class of highly conserved ...
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<p>Knockdown of lncRNA TUG1 Enhances Radiosensitivity of Prostate Cancer via the TUG1/miR-139-5p/SMC1A Axis</p>
... of TUG1 in PCa, qRT-PCR was performed to detect the expression of TUG1 in PCa tissues and ...of TUG1 was signi fi cantly increased in PCa tissues compared with the corresponding normal tissues (Figure ...
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The lncRNA <em>TUG1</em> promotes epithelial ovarian cancer cell proliferation and invasion via the WNT/β-catenin pathway
... IOSE80, lncRNA TUG1 was upregulated in the HO8910, SKOV3, and CAOV3 cell lines (Figure ...of TUG1 in 80 paired EOC and adjacent nontumor tissue samples. TUG1 was significantly upregulated in ...
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<p>Transcription factor <em>Nrf2</em> induces the up-regulation of lncRNA <em>TUG1</em> to promote progression and adriamycin resistance in urothelial carcinoma of the bladder</p>
... ed TUG1 associated with UCB progression. High expression of TUG1 has been documented to be correlated with enhanced UCB cell proliferation and ...of TUG1, and its knockdown facilitated the ...
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Screening of long non-coding RNA and TUG1 inhibits proliferation with TGF-β induction in patients with COPD
... Objective: To evaluate differentially expressed long noncoding RNAs (lncRNAs) and the potential role of lncRNA TUG1 in patients with chronic obstructive pulmonary disease (COPD). Methods: Total RNA was ...
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LncRNA-ANCR regulates the cell growth of osteosarcoma by interacting with EZH2 and affecting the expression of p21 and p27
... of lncRNA TUG1 reduced the prolifera- tion rate and increased apoptosis rate in OS cell [9], which indicated that lncRNAs may be considered as bio- markers for the diagnosis of OS and potential molecular ...
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<p>Metformin Activates the AMPK-mTOR Pathway by Modulating lncRNA <em>TUG1</em> to Induce Autophagy and Inhibit Atherosclerosis</p>
... follows: lncRNA TUG1 (human): forward 5 ′ -CCACTTTGTCACAAGAGA AGGC-3 ′ , reverse 5 ′ -CACAAATTCCCATCATTCCC-3 ′ ; lncRNA TUG1 (rat): forward 5 ′ -TGCTGAAGTTGTT TGCCTGC-3 ′ , reverse 5 ′ ...
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Effect of lncRNA ANRIL silencing on anoikis and cell cycle in human glioma via microRNA-203a
... of lncRNA ANRIL silencing on anoikis and the cell cycle in human glioma, and found that lncRNA ANRIL silencing could induce anoikis and cell cycle arrest in G0/G1 phase in U251 cells and that miR-203a ...
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LncRNA MEG3 promotes melanoma growth, metastasis and formation through modulating miR-21/E-cadherin axis
... of lncRNA MEG3, E-cadherin and miR- 21 were further examined using the SYBR-Green PCR Master Mix kit (TAKARA, Japan) on an ABI Prism 7900 Sequence Detection System (Applied Biosystems, ...human lncRNA MEG3 ...
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Original Article Overexpression of lncRNA-422 inhibits proliferation and invasion in colorectal cancer
... SW1116 cells were lysed with RIPA protein extraction reagent (Beyotime, Beijing, China) supplemented with a protease inhibitor cock- tail (Roche, CA, USA). Protein extracts (40 μg) were separated by 10% ...
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Original Article High expression of long noncoding RNA AB073614 in colorectal cancer patients and its clinical significance
... The present study didn’t find obvious correla- tions of lncRNA AB073614 level with tumor size, lymphatic metastasis and vascular inva- sion in the multivariate logistic regression anal- ysis (Table 2). This might ...
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Identification of long non-coding RNAs biomarkers for early diagnosis of myocardial infarction from the dysregulated coding- non-coding co-expression network
... analyzed lncRNA expression profiles of 151 samples (80 AMI patients and 71 healthy samples) by repurposing two publicly available microarray expression datasets to determine whether there is significantly altered ...
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Long noncoding RNA Braveheart promotes cardiogenic differentiation of mesenchymal stem cells in vitro
... during lncRNA-Bvht induced transdifferentiation of ...after lncRNA-Bvht transfaection, in- dicating that it might facilitate the cardiac lineage differenti- ation of ...after lncRNA-Bvht ...in ...
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