Local Drug Delivery
Local Drug Delivery System of Chitosan Strips Containing Sparfloxacin for Periodontal Disease
... An objective of periodontal treatment is to suppress or eliminate sub gingival periodontal pathogens. This is generally achieved through sub gingival debridement, resulting in the reduction of the total bacterial load. ...
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Nanotechnology Controlled Local Drug Delivery System for the Treatment of Periodontitis
... In the current data polymer, matrix-based nanocomposites have produced a significant amount of attention. The architecture of polymers or microparticle-based hydrogels influences the rate of release thereby, enabling ...
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Microspheres for local drug delivery in bone joints
... of drug delivery have certain disadvantages which can be improved ...A local drug delivery system (DDS) is, therefore, necessary which can deliver the drug at or to the diseased ...
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Oral local drug delivery: An overview
... Oral local drug delivery is a most efficient drug delivery approach than systemic drug delivery ...for drug application, into which more targeted delivery of ...
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Local Drug Delivery to Bone Joints with Microspheres
... of local drug delivery in the form of microspheres has potential for use as an alternative to conventional therapy strategies in the treatment of pain and inflammatory symptoms in case of certain ...
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Soft and flexible poly(ethylene glycol) nanotubes for local drug delivery
... Systemic delivery of anticancer drugs as part of an adjuvant chemotherapy regime for breast cancer patients is associated with severe adverse side ...20 Local drug delivery strategies ...
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LOCAL DRUG DELIVERY SYSTEMS IN THE TREATMENT OF PERIODONTITIS: A REVIEW
... the delivery of triclosan to periodontal ...The delivery of triclosan and chlorhexidine was studied for several liposomal compositions involving cationic as well as anionic ...
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Role Of Local Drug Delivery Agents In The Treatment Of Periodontal Diseases
... Tetracycline is available in the formn of fibers which, if placed locally can control or treat periodontal disease. They are non-resorbable cylindrical drug delivery devices made of a biologically inert, ...
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Nanoengineered drug-releasing Ti wires as an alternative for local delivery of chemotherapeutics in the brain
... curved Ti wire. The SEM images show randomly dispersed vertical cracks (width 1–1.5 µ m and .1 mm long) across the entire wire length (Figure 2B and C). The formation of these cracks is explained by radial growth of TNT ...
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Perioceutics in the management of Periodontal Disease
... of drug via local drug delivery system have shown to achieve better clinical results when used as an adjunct to conventional non-surgical periodontal therapy, as periodontal pockets holds ...
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Original Article Efficacy of tobramycin-loaded coating K-wire in an open-fracture rabbit model contaminated by staphylococcus aureus
... As indicated form results of the study, PDLLA was effective as a local drug delivery material for tobramycin application from titanium Kirs- chner wires at the fracture site to control bacte- rial ...
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Microneedles: An advancement to transdermal drug delivery system approach
... the drug through the hollow bore channel present in the ...the drug is allowed to pass through the bore which diffuses into the systemic circulation (Kurz et ...intradermal drug delivery ...
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ROLE OF NOVEL DRUG DELIVERY TECHNOLOGIES IN THE TREATMENT OF PERIODONTAL DISEASES
... periodontal disease, the expression of microbial pathogenic factors alone may not be sufficient to cause periodontitis.Therapeutic approaches include mechanical scaling and root planing (SRP) and in some cases surgery. ...
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... Localized delivery of the drug to a particular body compartment, which lowers the systemic drug level, reduces the need for follow up care, preserves medications that are rapidly destroyed by the ...
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A Review on Novel Techniques for Drug Delivery to the Brain
... Drug delivery to brain is still a challenging task due to the presence of the blood–brain barrier (BBB), a very restrictive barrier mainly composed of tightly sealed endothelial ...thus delivery of ...
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NIOSOME DRUG DELIVERY SYSTEM: ADVANCES AND MEDICAL APPLICATIONS AN OVERVIEW
... Niosomes, vesicular systems made of nonionic surfactants, have several advantages over conventional non-vesicle formulations. In recent years, Niosomes have become the vesicles of choice in drug delivery. ...
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TRANSDERMAL DRUG DELIVERY SYSTEM: A NOVEL DRUG DELIVERY SYSTEM
... controlled drug delivery has become increasingly important in the pharmaceutical ...of drug application both for local and systemic ...to drug penetration thereby limiting topical and ...
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Drug-eluting scaffold to deliver chemotherapeutic medication for management of pancreatic cancer after surgery
... nanoparticle-mediated drug delivery because of its potential ...the local delivery of a reduced dosage of FOLFIRINOX, a four-drug regimen comprising oxaliplatin, leucovorin, irinotecan, ...
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NANOPARTICULATE DRUG DELIVERY SYSTEMS: PROMISING APPROACHES FOR DRUG DELIVERY
... A further possibility for the production of drug nanocrystals in solid matrices is high-pressure homogenization in hot melts. It offers advantages over production in aqueous solution and subsequent spray drying. ...
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A BRIEF REVIEW ON MEDICATED CHEWING GUM’S
... useful delivery system for agents intended for systemic delivery. Drug that is released from MCGs within oral cavity can be absorbed via buccal ...
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