Locoregional control
A comparative evaluation of acute toxicity and locoregional control by concomitant chemoradiation therapy with or without neoadjuvant chemotherapy in locally advanced head and neck squamous cell carcinoma
... As stage wise response assessment was carried out it was seen that for stage III disease, 13 patients (86.7%) in the study arm had complete response and 2 patients (13.7%) had poorer response. In the control arm ...
6
Prediction of Locoregional Control in Head and Neck Squamous Cell Carcinoma with Serial CT Perfusion during Radiotherapy
... in a study of 105 patients treated with definitive radiation ther- apy for HNSCC, that the perfusion rate by using dynamic CT before treatment was a predictor for local outcome with lower pretreatment perfusion rates of ...
7
Primary surgery for locoregional advanced oropharyngeal cancer: prognostic factors
... As previously mentioned, NCCN guidelines4 for OPSCC defined several risk factors, namely extranodal extension, nodal disease in levels IV or V, positive surgical margins, pT3-4 stage, perineural infiltration and ...
7
Patterns of failure and survival in patients with nasopharyngeal carcinoma treated with intensity-modulated radiation therapy in Saudi Arabia
... were locoregional control, distant metastasis control, and disease-free survival ...(DFS). Locoregional recurrence was defined as the time from diagnosis to reappearance of locoregional ...
7
Comparison of altered fractionation schedule with concurrent chemo-radiation for squamous cell carcinoma of head and neck
... loco-regional control and has become the standard of care for locally advanced ...of locoregional control and survival, in altered fractionation, led many investigators to evaluate concurrent CTRT ...
5
<p>Characteristic And Novel Therapeutic Strategies Of Nasopharyngeal Carcinoma With Synchronous Metastasis</p>
... the one hand, IMRT could increase locoregional control, which might translate into survival bene fi t in patients with smNPC. On the other hand, relatively low incidence of grade 3/4 acute toxicities was ...
12
Tumor aromatase expression as a prognostic factor for local control in young breast cancer patients after breast conserving treatment
... ER β expression in breast (normal and tumor) and the relation between ERβ and other clinicopathologic features and its role in hormone therapy have been extensively investigated (recently reviewed by Zhao and others ...
11
Impact of age, tumor characteristics, and treatment on local control and disease outcome in early stage breat cancer : an EORTC translational research project
... after locoregional therapy alone, meaning that 20–30% of these patients will eventually develop distant metastases and subsequently die of breast ...better locoregional control in favour of the ...
152
Efficacy of intensity-modulated radiotherapy combined with chemotherapy or surgery in locally advanced squamous cell carcinoma of the head-and-neck
... In summary, the present study showed that IMRT combined with surgery or chemotherapy achieved excel- lent long-term locoregional control and OS in locally advanced [r] ...
7
Postmastectomy locoregional recurrence and recurrence free survival in breast cancer patients
... Many reports suggested that premenopausal and younger age at breast cancer diagnosis were unfavorable prognostic factors for locoregional control and survival [8,9,31]. In the study of Mansell et al, large ...
7
Delineation of clinical target volume for postoperative radiotherapy in stage IIIA-pN2 non-small-cell lung cancer
... high locoregional relapse rate and the improvement of radiation technology, postoperative radiotherapy (PORT) has been widely used in the treatment of completely resected stage IIIA-pN2 non-small-cell lung cancer ...
9
Rare Occurrence of a Poorly Differentiated Neuroendocrine Tumor of the Bladder
... Because most treatments for SCCB have not been proven through clinical research, the first phase II clinical trial for surgically resectable SCCB is groundbreaking. By adding a neoadjuvant chemotherapy regimen, groups of ...
5
Locoregional therapy of breast cancer: maximizing control, minimizing morbidity
... local control does impact long-term survival, the focus of breast cancer treatment should not be on how much locoregional recurrence is acceptable, but rather how we can achieve optimum control while ...
19
Hepatocellular carcinoma: early-stage management challenges
... Laparoscopic liver resection was first pioneered in the 1990s, though it was initially slow to gain popularity. Concerns among surgeons included loss of tactile feedback in an already challenging operation, reduced ...
12
Prognostic prediction across a gradient of total tumor volume in patients with hepatocellular carcinoma undergoing locoregional therapy
... undergoing locoregional therapy, therefore the strategy for selecting appropriate cutoffs of TTV for patients receiving other treatment modalities may not be the ...
11
Comparison of 3 image guided adaptive strategies for bladder locoregional radiotherapy
... precision locoregional irradiation due to the presence of 2 independent moving targets: the PLN, which is relatively immobile with respect to the bony anatomy, and the highly distensible bladder, whose volume and ...
9
Possible influence of mammographic density on local and locoregional recurrence of breast cancer
... This study is an extension of a large case-control study among all Swedish residents who were born in Sweden and who were 50 to 74 years old at the time of enroll- ment (1 October 1993 to 31 March 1995). Details ...
9
Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer
... already close to the assumed lifetime tolerance doses following prior irradiation. Treatment approaches that allow dose escalation for tumor control and can effectively spare normal tissue during re-irradiation ...
5
Surgical Margins in Breast Cancer: Finally Defined?
... Breast cancer is now recognized to be a heterogeneous disease with different behaviors. Both tumor burden and tumor biology contribute to its clinical outcomes. Adequate local control has been shown to confer a ...
9
Hypofractionated whole breast radiotherapy: current perspectives
... Regarding efficacy, the British Columbia randomized trial of postmastectomy RT (PMRT) used a 16-fraction treatment schedule. This trial randomly allocated 318 premenopausal women with node-positive breast cancer treated ...
8