Long-Acting Injection
Patient perspectives in the development and use of long-acting antipsychotics in schizophrenia: focus on olanzapine long-acting injection
... and long-acting injectable “depot” preparations of antipsychotic medications have been used as an alternative to oral medication therapy for patients for whom adherence is a clinically significant problem, ...
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Treatment-completion rates with olanzapine long-acting injection versus risperidone long-acting injection in a 12-month, open-label treatment of schizophrenia: indirect, exploratory comparisons
... risperidone long-acting injection study most similar to the single olanzapine long-acting injection study that was ...risperidone long-acting injection ...
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A pooled analysis of injection site related adverse events in patients with schizophrenia treated with olanzapine long acting injection
... Olanzapine long-acting injection (LAI) is a depot an- tipsychotic formulation consisting of a pamoate salt of olanzapine that is administered by deep intramuscular in- jection every 2 to 4 weeks ...
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Emerging treatments in the management of bipolar disorder – focus on risperidone long acting injection
... Risperidone long acting injection (RLAI) as a monotherapy or as adjunctive therapy to lithium or valproate for the maintenance treatment of bipolar I disorder was approved by Food and Drug ...
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Dose associated changes in safety and efficacy parameters observed in a 24 week maintenance trial of olanzapine long acting injection in patients with schizophrenia
... Olanzapine long-acting injection (LAI) has been studied in both the short-term [1] and long-term [2] treatment of ...have long been observed [6]. Among atypical depots, risperidone ...
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Risperidone long acting injection in Schizophrenia Spectrum Illnesses compared to first generation depot antipsychotics in an outpatient setting in Canada
... Background: Depot formulations of antipsychotics provide a potential solution to the poor adherence to oral therapies in schizophrenia. However, there have been few comparative studies on the effectiveness and ...
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A critical appraisal of paliperidone long-acting injection in the treatment of schizoaffective disorder
... a long-acting injection (LAI) addresses adherence issues, thus potentially reducing ...a long-term, double-blind, randomized, controlled trial of adult patients (n=334; intent-to-treat [ITT]) ...
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Profile of olanzapine long-acting injection for the maintenance treatment of adult patients with schizophrenia
... Olanzapine long-acting injection (OLAI) is a crystalline salt composed of olanzapine and pamoic acid, which permits a depot intramuscular formulation of ...a long-term, controlled trial of 24 ...
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Preparation and in vitro/in vivo evaluation of PLGA microspheres containing norquetiapine for long-acting injection
... The SEM images of NQ ⋅ 2HCl, NQ freebase, PLGA 502, PLGA 502H, and NQ freebase PLGA 502H microspheres are shown in Figure 1. NQ ⋅ 2HCl was shown to have an angular, crystalline form (Figure 1A). NQ freebase microspheres ...
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Treatment and control of bovine hypodermosis with ivermectin long acting injection (IVOMEC® GOLD)
... Conclusions: The results from this study demonstrate that ivermectin in a long-acting formulation is 100 % efficacious in the treatment of cattle naturally infested by H. bovis and H. lineatum larvae at all ...
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Pharmacogenetic evaluation to assess breakthrough psychosis with aripiprazole long acting injection: a case report
... new long-acting injectable formulation of ari- piprazole, aripiprazole lauroxil, was considered due higher dosing options (aripiprazole lauroxil 882 mg every 4- weeks, equivalent to aripiprazole LAI 600 mg) ...
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Post injection delirium/sedation syndrome in patients with schizophrenia treated with olanzapine long acting injection, I: analysis of cases
... proper injection technique does not guarantee that a blood vessel injury has not occurred during the injection process, it is therefore necessary to observe the patient following each ...each ...
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Olanzapine long acting injection: a review of first experiences of post injection delirium/sedation syndrome in routine clinical practice
... in-hospital injection (22 cases) remained in hospital; it is not known whether these events in themselves would have merited hospital- isation or an extension of ...
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Post injection delirium/sedation syndrome in patients with schizophrenia treated with olanzapine long acting injection, II: investigations of mechanism
... equilibrium solubility of the salt could dissolve. Under static conditions, a hematoma consisting of 20 mL blood would appear to be required for the dissolution of approximately 20 mg olanzapine (based upon the 0.986 ...
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Combination treatment with risperidone long-acting injection and psychoeducational approaches for preventing relapse in schizophrenia
... Abstract: A recent meta-analysis showed that long-acting injectable (LAI) antipsychotics were not superior to oral antipsychotics for preventing relapse in patients with schizophrenia. We there- fore ...
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Efficacy and safety of risperidone long-acting injection in elderly people with schizophrenia
... preferred. Long- acting risperidone is the first such antipsychotic available for use in this vulnerable group of patients and offers an attractive alternative to traditional ...that ...
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Long-term functional improvements in the 2-year treatment of schizophrenia outpatients with olanzapine long-acting injection
... Methods: This study describes changes in the levels of functioning among outpatients with schizophrenia treated with olanzapine-LAI compared with oral olanzapine over 2 years. This was a secondary analysis of data from a ...
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Schizophrenia symptoms and functioning in patients receiving long term treatment with olanzapine long acting injection formulation: a pooled analysis
... The objective of the analyses reported is to evaluate how non-acute schizophrenia patients with different baseline status develop in terms of their symptoms and functioning during maintenance treatment as analyzed by ...
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Patient perspectives on use of long-acting antipsychotics in bipolar disorder: focus on risperidone injection
... patients. Long-acting injectable formulations of second-generation antipsychotics could combine the effect of oral second-generation antipsychotics in patients with bipolar disorder and the benefits of ...
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Long acting olanzapine versus long acting risperidone for schizophrenia in Spain – a cost effectiveness comparison
... and long-acting injection formulations of risperidone and other antipsychotics for the treatment of non-adherent and partially adherent patients with schizophrenia within the United States healthcare ...
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