Long-acting insulin
Mechanism of exercise induced hypoglycemia in depancreatized dogs maintained on long acting insulin
... immunoreactive insulin indicating either that some released insluin was not active or that a moderate immunoreactive insulin increment induced a near-maximal ...zinc insulin, exercise accelerates ...
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Treatment intensification using long-acting insulin –predictors of future basal insulin supported oral therapy in the DIVE registry
... Risks were expressed in terms of unadjusted and mul- tivariable adjusted hazard ratios (HRs) with 95 % CIs ob- tained from Cox proportional hazards models regarding the event of interest ‘Initiation of BOT’ (state 1). ...
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Insulin analogues dosing and costs - comparing real-life daily doses of insulin detemir and insulin glargine in type 2 diabetes patients
... daily insulin dose. Nei- ther concomitant insulin use nor use of non-insulin anti- diabetic medication was ...concomitant insulin use and use of non- insulin anti-diabetic medication ...
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IJPCBS 2013, 3(2), 242-246 Sandozi Tasneem et al. ISSN: 2249-9504 242
... peakless insulin which has a broad plasma concentration plateau and is an ultra long acting insulin ...hour insulin coverage than ultlralente or NPH ...
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An update on the treatment of type 1 and type 2 diabetes mellitus: focus on insulin detemir, a long-acting human insulin analog
... with insulin analogs versus regular human insulin or one long-acting insulin analog versus ...comparing insulin detemir and NPH insulin in 2558 type 1 DM adult patients, ...
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Lixisenatide: evidence for its potential use in the treatment of type 2 diabetes
... first-phase insulin release in patients with type 2 diabetes and improves the second-phase insulin ...and long-acting insulin analogs have demonstrated protective effects on beta cells ...
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Safety, effectiveness, and cost of long-acting versus intermediate-acting insulin for type 1 diabetes: Protocol for a systematic review and network meta-analysis
... contact insulin manufacturers, scan the reference lists of included studies and relevant reviews, and contact prolific authors of T1DM long-acting insulin ...
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Click here to download PDF version of the article !
... a long acting insulin which is injected subcutaneously once daily in patients with type 1 or 2 DM; its onset of action is about an hour and create a relatively stable concentration of insulin ...
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GLYCEMIC CONTROL WITH DIFFERENT TYPES OF INSULIN IN THE MANAGEMENT OF GESTATIONAL DIABETES MELLITUS
... levels. Insulin Glargine, the first long-acting insulin analogue was approved for clinical use in patients with Type 1 and Type 2 diabetes in 2000 and it was introduced in 2001 in the ...USA. ...
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A prospective randomised cross-over study of the effect of insulin analogues and human insulin on the frequency of severe hypoglycaemia in patients with type 1 diabetes and recurrent hypoglycaemia (the HypoAna trial): study rationale and design
... of insulin-treated diabetes with respect to glycae- mic control and avoidance of hypoglycaemic ...Short-acting insulin analogues (aspart, lispro and gluli- sine) were designed to mimic the fast ...
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Nephrotoxicity in Recipients of Vancomycin vs. Vancomycin with Vitamin C
... by insulin deficiency.Insulin degludec is newly developed ultra-long-acting insulin ...of insulin degludec on the artery is ...of insulin degludec on ...bolus insulin ...
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Pharmacokinetics and pharmacodynamics of insulin analogs in special populations with type 2 diabetes mellitus
... or long-acting insulin ...of insulin analogs may seem subtle, they may account for the difficulties encountered by providers when establishing glycemic ...affecting insulin PK/PD may ...
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Is Postprandial Glucose Control Important? Is It Practical In Primary Care Settings?
... (including insulin injection); self-monitoring of blood glucose (SMBG); utilization of pat- tern management to adjust therapy; prevention/treatment of hypo- glycemia; and general health main- tenance (foot exams, ...
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Large pre and postexercise rapid acting insulin reductions preserve glycemia and prevent early but not late onset hypoglycemia in patients with type 1 diabetes
... rapid- acting insulin dose, which protected all patients from hypoglycemia throughout the postexercise meal period, whereas blood glucose concentrations declined under both Full and 75% doses ...of ...
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Combination therapies in the management of type 2 diabetes: the use of insulin degludec/liraglutide
... Abstract: The global burden of type 2 diabetes is estimated to currently affect over 350 million people worldwide and is anticipated to continue increasing over the next 20 years. Current treatment guidelines recommend ...
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Long-acting preparations of exenatide
... the acting time of exenatide by preparing sustained-release dosage forms, modifying its structure, gene therapies, and other ...in long- acting exenatide ...
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Cost-effectiveness analysis of a fixed-dose combination of indacaterol and glycopyrronium as maintenance treatment for COPD
... Objective: The aim of this study was to evaluate the cost-effectiveness of the long-acting beta-2 agonist (LABA)/long-acting muscarinic antagonist (LAMA) dual bronchodilator indacaterol[r] ...
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Insulin degludec as an ultralong-acting basal insulin once a day: a systematic review
... 24 hours with the glucose clamp technique (Biostator; Miles Laboratories, Elkhart, IN). IDeg produced significantly less pharmacodynamic variability than IGlar on all protocol pharmacodynamic variability parameters, ...
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A comparison of tiotropium, long-acting β2-agonists and leukotriene receptor antagonists on lung function and exacerbations in paediatric patients with asthma
... This literature review compares the efficacy and safety of long-acting β 2 -agonists (LABAs), leukotriene receptor antagonists (LTRAs) and long-acting muscarinic antagonists (LAMAs) as a[r] ...
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Inhaled drugs to reduce exacerbations in patients with chronic obstructive pulmonary disease: a network meta-analysis
... general, long-acting beta-agonists or anticholinergics appear to be the treatment of choice to reduce exacerba- tion ...and long-acting anticholinergics should be favored because they reduce ...
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