Long term safety
Rationale and design of the VISION study: a randomized, open-label study to evaluate the long-term safety of vonoprazan as maintenance treatment in patients with erosive esophagitis
... However, long-term data on vonoprazan use are ...the long-term efficacy and safety of vonoprazan in comparison with the PPI ...mg). Safety populations in both phases are defined ...
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Long-term safety and efficacy of infliximab for the treatment of ankylosing spondylitis
... on long-term efficacy and safety of infliximab in AS, with special emphasis on axial and extra- articular disease, predictors of response, and radiological ...the long-term effects of ...
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Long-term safety and efficacy of budesonide in the treatment of ulcerative colitis
... Abstract: Ulcerative colitis (UC) is a chronic, relapsing, and remitting inflammatory disease involving the large intestine (colon). Treatment seeks to break recurrent inflammation episodes by inducing and maintaining ...
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An open-label study to evaluate the long-term safety and efficacy of lanadelumab for prevention of attacks in hereditary angioedema: design of the HELP study extension
... the long-term safety of repeated subcutaneous administrations of lanadelumab in patients with type I/II ...and safety/efficacy in patients who switch to lanadelumab from another pro- phylactic ...
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Long-term safety of biologics in the treatment of psoriasis
... Lastly, safety registries allow prospective systematic collection of large quantities of “real world” data over prolonged periods, so can provide valuable data on long-term safety and ...
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Long-term safety of aromatase inhibitors in the treatment of breast cancer
... 4. Extended hormonetherapy strategy: The duration of hormonal treatment in adjuvant situation is an old question, but remains a fundamental issue. Results from the EBCTG analysis (EBCTCG 2005) clearly demonstrated that 5 ...
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Long Term Safety and Efficacy of Tacrolimus in Myasthenia Gravis
... that long-term treatment with tacrolimus may improve the clinical status and decrease the re- quired dose of oral prednisolone in patients with ...a long and intractable disease courses, the ...
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Long-term safety and efficacy of etanercept in the treatment of ankylosing spondylitis
... Abstract: To date, anti-tumor necrosis factor alfa (anti-TNF-α) therapy is the only alternative to nonsteroidal anti-inflammatory drugs for the treatment of ankylosing spondylitis. Etanercept is a soluble TNF receptor, ...
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Long-term safety and efficacy of romiplostim for treatment of immune thrombocytopenia
... The incidence of adverse events in each cohort of patients receiving long-term romiplostim treatment for chronic ITP is summarized in Table 3. Treatment-related adverse events were highest in cohort 1: the ...
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<p>Efficacy and safety of controlled-release oxycodone for the management of moderate-to-severe chronic low back pain in Japan: results of an enriched enrollment randomized withdrawal study followed by an open-label extension study</p>
... Patients and methods: An initial enriched enrollment randomized withdrawal, double-blind, placebo-controlled, 5-week phase III trial was conducted across 54 centers in Japan to assess the efficacy of S-8117 vs placebo in ...
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Long-term Efficacy and Safety of Laronidase in the Treatment of Mucopolysaccharidosis I
... the long-term safety and efficacy of laronidase among children and adults with attenuated MPS I disease and a wide range of long-standing clinical ...that long-term use of enzyme ...
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Long-term effectiveness and safety of sirolimus drug-eluting stents
... the long-term safety and efficacy of drug-eluting stents, due to the occur- rence of late adverse clinical events, such as stent ...pharmacology, safety, and various therapeutic options that ...
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Long-term efficacy and safety of raltegravir in the management of HIV infection
... alike, including patients with extensive antiretroviral history and documented antiretroviral resistance. Studies have also exhibited low adverse effect rates and reliable long-term safety lending to ...
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Deferasirox: appraisal of safety and efficacy in long-term therapy
... the long term in both pediatric and adult ...during long-term deferasirox treatment. Long-term safety of iron chelators is critical in β -thalassemia patients, since most ...
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Long-term efficacy and safety of human papillomavirus vaccination
... Recently, a pooled analysis of large-scale and long-term safety data from the 42 completed/ongoing clinical trials with bHPV vaccine has been published. Overall, 31,173 adolescent girls/women ...
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Five-year follow-up of a woman with pregnancy and lactation-associated osteoporosis and vertebral fractures
... shows long-term changes in bone turnover markers and lumbar spine bone mineral density, as well as long-term safety of alfa- calcidol treatment in a young woman with pregnancy and ...
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Linagliptin as add-on therapy to insulin for patients with type 2 diabetes
... CV safety studies since preclinical research and post hoc analyses of clinical trials have come up with interesting findings suggesting a positive cardiovascular risk profile of DPP-4 ...
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Effects of treatment with bimatoprost 0.03% for 3 years in patients with normal-tension glaucoma
... The objective of the present study is the efficacy of the drug in decreasing IOP, maintenance efficacy of the visual field, and to investigate the safety of long-term administration of bimatoprost ...
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Quality Improvement on the Long-term Care Ventilator Unit: Interventions to Increase Patient Safety and Prevent Patient Harm
... Quality Improvement on the Long-term Care Ventilator Unit: Interventions to Increase Patient Safety and Prevent Patient Harm.. Billie Anderson.[r] ...
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Clinical use, safety and effectiveness of novel high cost anticancer therapies after marketing approval: a record linkage study
... Healthcare databases are a uniquely useful source of data for pharmacoepidemiologic investigations and for comparative effectiveness research [18, 19]. The main advantages of such an approach are the representativeness ...
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