long-term synaptic potentiation
A computational simulation of long-term synaptic potentiation inducing protocol processes with model of CA3 hippocampal microcircuit
... An experimental study of computational model of the CA3 region presents cog- nitive and behavioural functions the hippocampus. The main property of the CA3 region is plastic recurrent connectivity, where the connections ...
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Memory and forgetting processes with the firing neuron model
... The aim of this paper is to present a novel algorithm for learning and forgetting within a very simplified, biologically derived model of the neuron, called firing cell (FC). FC includes the properties: (a) delay and ...
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Emulating long-term synaptic dynamics with memristive devices
... observed synaptic modification, as indicated by a positive or negative percentage change in conductance, was recorded for a range of initial conductance ...of synaptic modification was plotted against the ...
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On the role of arachidonic acid in long-term potentiation
... in synaptic vesicles at the axon terminal. There are two classes of synaptic contact, based on their effects upon the postsynaptic membrane potential; excitatory, tending to lead to the firing of an action ...
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No requirement of TRPV1 in long-term potentiation or long-term depression in the anterior cingulate cortex
... of synaptic plasticity, long-term potentiation (LTP) and long-term depression (LTD), in the anterior cingulate cortex ...
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Synaptic tagging and capture : differential role of distinct calcium/calmodulin kinases in protein synthesis dependent long term potentiation
... strong and weakly tetanized pathways) (Fig. 6B, p ⬎ 0.05). A parsi- monious explanation for this would be the contribution of Figure 5. STO-609 dissects a role for CaMKK in a cell-wide process necessary for late-LTP. A, ...
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Expression mechanisms underlying different forms of hippocampal long-term potentiation
... phenomenon might occur. These include an increased uptake of dye into other non- releasing vesicle pools or into non-vesicular compartments such as endosomes. Alternatively such an increase could result from a change in ...
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Seasonal variation of long term potentiation at a central synapse in the medicinal leech
... during the winter months and that both forms of synaptic plasticity are NMDAR dependent (Grey et al., 2009; Grey and Burrell, 2010) may indicate that NMDAR levels are reduced during the winter. Walton and ...
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Neurobiological Bases of Learning and Their Role for the Paradigm Shift in Education
... in synaptic function, that is to say, the gain or loss of func- tion considered as a whole, making this a remodeling phenomenon and thus learning (Abraham, ...migration, long term potentiation ...
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Neocortical long-term potentiation and experience-dependent synaptic plasticity require alpha-calcium/calmodulin-dependent protein kinase II autophosphorylation
... Previous studies using knock-out mice had concluded that ␣CaMKII is required for hippocampal LTP (Silva et al., 1992). The same point mutation in ␣CaMKII studied here has also been shown to almost completely block LTP in ...
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Imaging synaptic plasticity
... investigate long-term changes in synaptic efficacy following the electrical, pharmacological, or genetic manipulation of synaptic ...of long-term potentiation (LTP), as ...
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Long term potentiation decay and memory loss are mediated by AMPAR endocytosis
... AMPAR synaptic localization and PKMζ expression in the hippocampi of animals subjected to either wIA or sIA ...of synaptic AMPARs) but this would be grad- ually counteracted by a secondary ...
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An investigation of the processes underlying late-phase long-term potentiation
... incorporation (Feig and Lipton, 1993). This dendritic protein synthesis was dependent on NMDA and muscarinic receptor activation and did not occur in response to either stimulation or carbachol application alone. ...
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Erythropoietin enhances hippocampal long-term potentiation and memory
... excitatory synaptic transmission was decreased upon EPO treatment, whereas inhibitory synaptic transmission was ...active synaptic connec- ...
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Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats
... pain. Long-term potentiation (LTP) of insular excitatory synaptic transmission is believed to mediate pathological pain [12, ...Basic synaptic transmission is mainly mediated by ...
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Roth-Alpermann, Claudia (2005): Homeostatic regulation of long-term potentiation. Dissertation, LMU München: Fakultät für Biologie
... global synaptic strength can operate over a timeframe of several days (Turrigiano et ...runaway synaptic strengthening might be necessary, especially in highly plastic brain structures such as the ...
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Effect of Gallic Acid on Dementia Type of Alzheimer Disease in Rats: Electrophysiological and Histological Studies
... mediating synaptic disruption has been examined by studying their direct effects on synaptic mechanisms, especially long-term potentiation ...in synaptic strength that is ...
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Cholinergic modulation of hippocampal long-term potentiation in chronic cerebral hypoperfused rats
... As evidenced in Figure 4A, the LTP of the 2VO group was significantly impaired compared to the SHAM- operated group following TBS. The result is in accordance with the findings of previous studies suggesting that 2VO ...
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Endogenous acetylcholine modulates synaptic plasticity in the hippocampus in vivo
... the long-lasting, protein synthesis-dependent stages o f long-term m emory and synaptic ...short-term synaptic function but may also promote the transcription and translation o f ...
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Differential regulation of synaptic plasticity of the hippocampal and the hypothalamic inputs to the anterior thalamus
... thalamocortical synaptic transmission undergoes potentiation mediated by TrkB receptors (Tsanov and Manahan-Vaughan, ...The long-term response to 900 pulses delivered with rate of 1Hz suggests ...
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