Low–grade squamous intraepithelial lesion:
Original Article p16INK4a and Ki-67 measurement predict progression of cervical low-grade squamous intraepithelial lesion
... of low-grade squamous intraepithelial lesion/cervical intraepi- thelial neoplasia grade I (LSIL/CIN1), and to analyze the predictive values of p16INK4a and Ki-67 for LSIL/CIN1 ...
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Cytologic surveillance versus immediate colposcopy for women with a cervical smear diagnosis of low-grade squamous intraepithelial lesion in a poor setting in Nigeria
... colposcopy, low-grade squamous intraepithelial lesions, Enugu Introduction Papanicolaou smear cytology has remained a important tool in the screening for cervical ...atypical squamous ...
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Comparison of Linear Array and Line Blot Assay for Detection of Human Papillomavirus and Diagnosis of Cervical Precancer and Cancer in the Atypical Squamous Cell of Undetermined Significance and Low Grade Squamous Intraepithelial Lesion Triage Study
... We evaluated Linear Array (LA), a newly commercialized PGMY09/11 L1 consensus primer PCR test that detects 37 human papillomavirus (HPV) genotypes by reverse line blot hybridization, for[r] ...
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Type-specific high-risk human papillomavirus viral load as a viable triage indicator for high-grade squamous intraepithelial lesion: a nested case–control study
... high-grade squamous intraepithelial lesion or worse; NILM/LSIL, negative for intraepithelial lesion or malignancy/low-grade squamous intraepithelial ...
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Colposcopic characteristics and Lugol׳s staining differentiate anal high-grade and low-grade squamous intraepithelial lesions during high resolution anoscopy
... Each lesion was evaluated and coded for the presence or absence of speci fic lesion characteristics using colposcopic criteria commonly used in gyne- cology and previously validated for anal lesions ...AWE ...
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Original Article Feasibility and efficacy of vaginectomy for patients with vaginal vault high-grade squamous intraepithelial lesion after hysterectomy: a retrospective analysis of 52 cases
... high-grade squamous intraepithelial lesion (HSIL) after hysterectomy is some- times seen and the treatment is ...and low incidence of postoperative complications ...was low ...
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Comparison of the diagnostic value of cervical cytology and HPV HR DNA testing for the diagnosis of low-grade and high-grade squamous intraepithelial lesions across different age groups
... MATERIAL AND METHODS Between 2011 and 2014, 1103 patients aged 25 and older underwent in-depth diagnostics at the Laboratory of Cervical Pathophysiology, Gynecology and Obstetrics Clinical Hospital, Karol Marcinkowski ...
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Use of colposcopy for detection of squamous intraepithelial lesions
... as squamous metaplasia, which includes proliferation of undifferentiated reserve cells, columnar cells and their transformation into the squamous ...at low grade level (LGSIL) and during the ...
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γH2Ax Expression as a Potential Biomarker Differentiating between Low and High Grade Cervical Squamous Intraepithelial Lesions (SIL) and High Risk HPV Related SIL.
... well as to determine whether γH2AX can be used as a biomarker to identify early HPV lesions with high-risk oncogenic potential. Our data suggest that there is a different expression of the γH2AX between the basal and ...
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A low-cost HPV immunochromatographic assay to detect high-grade cervical intraepithelial neoplasia
... Only a cohort study could answer this issue. However, one question remains: would it be ethi- cally acceptable not to offer any treatment to women with a confirmed diagnoses of CIN3 and HPV16/18 infection? Table 6. ...
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Expression of Messenger RNA of Oncoproteins E6 and E7 of Human Papilomavirus in Women with Negative Oncotic Cytologies, Epithelial Squamous Atypias of Undefined Significance and Low Grade Intraepithelial Lesions
... and/or squamous intraepithelial neoplasy grade I (SIN 1) of the lower genital tract (LGT); to relate the RNAm expression with viral infection types; to assess the genotyping in single ...with ...
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Evaluation of Reid’s Combined Colposcopic Index as a predictor of cervical intraepithelial lesion
... into Low grade disease predicting histological diagnosis of CIN1 in 47, Intermediate grade disease predicting histological diagnosis of CIN1/2 in 11 and High grade disease predicting ...
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Increased expression of sialic acid in cervical biopsies with squamous intraepithelial lesions
... the grade of squamous intrae- pithelial lesion (SIL) ...in low- and high-grade cervical intrae- pithelial lesions in order to determine the changes in sialylation at early stages of ...
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Peripheral blood lymphocytes from low-grade squamous intraepithelial lesions patients recognize vaccine antigens in the presence of activated dendritic cells, and produced high levels of CD8 + IFNγ + T cells and low levels of IL-2 when induced to proliferate
... These results are consistent with the notion that Th1 profile is necessary for the resolution of infection, as IL- 2 production shows a deficiency that is reflected beyond the local level, to the periphery. However, we ...
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High-grade squamous intraepithelial lesion arising adjacent to vulvar lymphangioma circumscriptum: a tertiary institutional experience
... Patient 2 was a 49-year-old woman who presented with edema and erythema of the right labium majora. Some vesicles, oozing clear fluid, were also noted on the vulva. Eight years earlier, she had undergone a radical ...
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High Risk HPV E6/E7 Oncoprotein Expression in Women with High Grade Squamous Intraepithelial Lesion
... Nevertheless, the detection of DNA only indicates the presence of HPV 7 and few infections are associated with lesions that progress toward malignancy. For this to occur there should be an overexpression of the E6 and E7 ...
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Biomarkers Expression in Cervical Cancer and High Grade Squamous Intraepithelial Lesions
... HIF-1α, VEGF and EpoR expression were analyzed in tissue samples by immunohistochemistry using commercial antibodies. Expression and overexpression of the tumor markers were quantified according to German Immunoreactive ...
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Review Article High-grade Prostatic Intraepithelial Neoplasia of the Prostate: The Precursor Lesion of Prostate Cancer
... Impact of HGPIN on Prostate Cancer Research There are many benign and malignant conditions in the prostate mimicking HGPIN. Since HGPIN is a microscopic finding, only pathologists or investigators with substantial ...
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Detection of HPV RNA molecules in stratified mucin producing intraepithelial lesion (SMILE) with concurrent cervical intraepithelial lesion: a case report
... mucin-producing intraepithelial lesion (SMILE) is a rare precursor lesion in the uterine cervix that is considered a variant of adenocarcinoma in situ ...
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Sensitivity and specificity of HR HPV E6/E7 mRNA test in detecting cervical squamous intraepithelial lesion and cervical cancer
... DISCUSSION According to the paper by Sørbye et al. published in 2014, diagnostic tests detecting HR HPV E6/E7 mRNA are characterized by a higher specificity than tests identify- ing HR HPV DNA. Comparative studies were ...
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