lung adenocarcinoma A549 cells
Nanostructured delivery system for zinc phthalocyanine: preparation, characterization, and phototoxicity study against human lung adenocarcinoma A549 cells
... human lung adenocarcinoma A549 cells. Cells were incubated with free ZnPc or ZnPc-loaded NPs for 4 h and then washed with phosphate-buffered ...the cells. Finally, the ...
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Original Article Effects of okadaic acid combined with cisplatin on the proliferation and apoptosis of human lung adenocarcinoma A549 cells
... in lung cancer ...of lung cancer achieving favorable efficacy. However, lung cancer in some pa- tients is progressively resistant to the plati- num based chemotherapy, resulting in a poor ...human ...
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RGD-modified liposomes enhance efficiency of aclacinomycin A delivery: evaluation of their effect in lung cancer
... Abstract: In this study, long-circulating Arg-Gly-Asp (RGD)-modified aclacinomycin A (ACM) liposomes were prepared by thin film hydration method. Their morphology, particle size, encapsulation efficiency, and in vitro ...
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Recombinant Newcastle disease virus rL RVG enhances the apoptosis and inhibits the migration of A549 lung adenocarcinoma cells via regulating alpha 7 nicotinic acetylcholine receptors in vitro
... cancer cells since the early 1980s, and the homomeric α7 nAChR accelerates proliferation, migra- tion, angiogenesis, neurogenesis and metastasis in most common human cancers by stimulating the synthesis and ...
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Chemosensitivity of radioresistant cells in the multicellular spheroids of A549 lung adenocarcinoma
... few cells survived, proliferated and relapsed after prolonged ...descendant cells was slow with low sensitivity to radiation ...radioresistant cells may result in reduction and resistant, or ...
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ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF SELECTED PLANT EXTRACTS AGAINST HUMAN NON SMALL CELL LUNG ADENOCARCINOMA (A549), HUMAN COLON CARCINOMA CELLS (HCT116) AND CHINESE HAMSTER NORMAL OVARY CELLS (AA8)
... Research studies are currently geared in the evaluation and determination of the cytotoxicity and antioxidant activity of plant extracts. These are important in obtaining possible plant-based anti- oxidant-supplements ...
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The long non-coding RNA HNF1A-AS1 regulates proliferation and metastasis in lung adenocarcinoma
... RIP experiments were performed using the Mag na RIP™ RNA-Binding Protein Immunoprecipitation Kit (Millipore, Billerica, MA, USA) according to the manufacturer’s protocol. Antibodies used in the DNMT1 RIP assays were ...
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Interferon gamma induces prostaglandin G/H synthase 2 through an autocrine loop via the epidermal growth factor receptor in human bronchial epithelial cells
... epithelial cells (NHBECs), interferon-gamma (IFN-gamma, 10 ng/ml for 24 h) increased the amount of prostaglandin E2 (PGE2) released in response to stimulation with exogenous arachidonic acid (5 ...in A549 ...
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B7-H3 promotes metastasis, proliferation, and epithelial-mesenchymal transition in lung adenocarcinoma
... transfecting A549 cells with B7-H3-siRNA or a scrambled siRNA, green fluorescence was observed in the ...of A549 cells, indicating that B7-H3 was involved in cell cycle progression and cell ...
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RNF4-mediated SUMOylation is essential for NDRG2 suppression of lung adenocarcinoma
... We next performed Nickel pull-down assays. A549 cells were transiently transfected with WT or mutant NDRG2, alone or with His-tagged SUMO1 and RNF4, in presence of MG132 (Figure 3A). Cell extracts were ...
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Efficacy of adjuvant chemotherapy for non-small cell lung cancer assessed by metastatic potential associated with ACTN4
... In order to develop a predictive biomarker for efficacy of ADJ, we reanalyzed patient data using a public database enrolled by JBR.10, which was a clinical trial to probe the clinical benefits of ADJ in stage-IB/II ...
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TGFβ upregulates PAR-1 expression and signalling responses in A549 lung adenocarcinoma cells
... in A549 cells at baseline, stimulating cells with thrombin and the PAR-1 activating peptide, TFLLR, produced a delayed and modest release of intracellular calcium as determined by monitoring changes ...
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Ligand-dependent differences in estrogen receptor beta-interacting proteins identified in lung adenocarcinoma cells corresponds to estrogenic responses
... and A549 cells were incubated with FLAG-ERb as described in Materials and ...and A549 cell lysates incubated with purified rhFLAG-ERb protein but not in H1793 or A549 cell extracts incubated ...
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Journal of Applied Pharmaceutical Science
... (breast adenocarcinoma), HepG2 (hepatocellular carcinoma), HT29 (colon carcinoma), A549 (lung carcinoma) and MDBK (bovine kidney) cells, obtained from National Cell Bank of Iran, were used to ...
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Overexpression of RBM5 induces autophagy in human lung adenocarcinoma cells
... on lung cancer cells in vivo, A549 xenografts were treated with control plasmid or GV287-RBM5 plasmid via attenuated ...in A549 xenografts in previous studies [18, ...
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Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells
... cancer cells and higher levels of CAXII were also found in chemoresistant lung cancer A549/dx cells compared to chemosensitive A549 cells (Figure ...U2-OS cells with ...
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Synthesis and Cytotoxic Evaluation of Bisphosphoramidates in A549 Human Lung Adenocarcinoma Cell Line
... or 6 at same concentration range and cisplatin and hydrogen peroxide as positive and negative control respectively The two active compounds 4 and 6, decreased the cell viability significantly when compared with ...
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Therapeutic Evaluation of microRNAs by Molecular Imaging
... (colon adenocarcinoma), CT-26 (colon adenocarcinoma), TPC-1 (papillary thyroid carcinoma), NPA (papillary thyroid carcinoma), U-2OS (osteogenic sarcoma), HeLa (cervical cancer), A549 (non-small ...
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Mechanisms of lung fibrosis induced by carbon nanotubes: towards an Adverse Outcome Pathway (AOP)
... human lung adenocarcinoma epithelial cell line; AM: alveolar macrophages; AO: adverse outcome; AOP: adverse outcome pathway; ATII: primary human alveolar type-II epithelial cells; BEAS-2B: bronchial ...
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Cytotoxic activity of L-asparaginase isolated from endophytic aspergillus nomius of Justicia adhatoda on A549 cell lines
... The A549 lung adenocarcinoma cell line was procured from National Centre for Cell Science, Pune, India, with the passage number of ...24. Cells were maintained in Dulbecco’s Minimum Essential ...
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