Lung infections
Comparative genomics of isolates of a pseudomonas aeruginosa epidemic strain associated with chronic lung infections of cystic fibrosis patients
... This study focusses on seven isolates of the P. aeruginosa LES: LES400, LES431 and LESB65, which were isolated in the UK and exhibit varying levels of virulence in a murine respiratory infection model [13], and four ...
15
Study of Secondary Lung Infections in Newly Diagnosed Pulmonary Tuberculosis
... Secondary lung infection is one of the most important complications in patients with pulmonary ...secondary lung infections in pulmonary tuberculosis and hence, the need for our ...
6
Treatment Strategies for Reducing Damages to Lungs in Coronavirus and Other Lung Infections
... If the virus infects one alveolus, the virus may quickly damage the alveolus. The air space of alveolus is in close proximity (0.2 µm) to pulmonary capillaries [11]. Air is exchanged around 10 to 15 times a minute. If ...
31
Immune risk phenotype is associated with nosocomial lung infections in elderly in-patients
... nosocomial infections, we found that the group with nosocomial infections had significantly lower values for the CD4/CD8 ratio and naive CD8 and CD4 T-cell counts and higher counts of memory CD8 T- cells ...
7
Bacterial activity in cystic fibrosis lung infections
... In the case of bands not being detected in the correspond- ing RT-T-RFLP analysis, it is likely that these bacteria were either dead or active at very low metabolic rates. The iden- tification of bands in RT-T-RFLP ...
12
Virally Delivered Cytokines Alter the Immune Response to Future Lung Infections
... previous infections or vaccination with RSV ...and lung eosinophilia and enhanced dis- ease during RSV infection, but this disease has recently been shown to be abrogated by the reduction of carbonyl groups ...
7
Case Report A case of reduced Th17 cell numbers in a 61-year-old man with hyper IgE syndrome
... Abstract: Hyper immunoglobulin E syndrome (HIES) is a rare primary immunodeficiency disorder characterized by eczema, recurrent skin and lung infections, and significantly elevated plasma IgE levels. ...
5
Cystic Fibrosis: A Review
... Nutritional therapy can improve strength and ability to stay active. It also can improve growth and development in children. Nutritional therapy also may make strong enough to resist some lung infections. A ...
7
Molybdate transporter ModABC is important for Pseudomonas aeruginosa chronic lung infection
... chronic lung infections [43], reduced biofilm production in STM_modA may be related to the virulence defect observed in the rat model of chronic lung infection, in conjunction with anaerobic growth ...
9
Life-Threatening Pneumopathy and U urealyticum in a STAT3-Deficient Hyper-IgE Syndrome Patient
... repeated lung infections, and periinfectious, noneczematic skin lesions, food polyallergy, total immunoglobulin E levels >1000 kUI/L, and moderate asthma with chronic reversible obstructive ...
6
Binding of nonmucoid Pseudomonas aeruginosa to normal human intestinal mucin and respiratory mucin from patients with cystic fibrosis
... Binding of nonmucoid Pseudomonas aeruginosa to normal human intestinal mucin and respiratory mucin from patients with cystic fibrosis.. Lung infections due to Pseudomonas aeruginosa and [r] ...
10
Individualized therapy for Cystic Fibrosis using artificial intelligence
... Cystic Fibrosis (CF) is the most common lethal hereditary disorder with autosomal recessive heredity in Caucasians (Ratjen, 2001) that affects approximately 30,000 people in the United State, and 70,000 people worldwide. ...
92
The Triggering Receptor Expressed on Myeloid Cells 2 Inhibits Complement Component 1q Effector Mechanisms and Exerts Detrimental Effects during Pneumococcal Pneumonia
... upon lung infections and since we observed a modest increase in neutrophil influx early during pneumococcal pneumonia in Trem-2 2/2 mice, these cells could contribute to the enhanced bacterial clearance in ...
17
Alginate/Chitosan Particle Based Drug Delivery Systems for Pulmonary Applications
... with lung infections (via inhibition of neutrophil elastase activity) and enhance their interaction with cystic fibrosis mucus (assayed via reduction of the depth of particle penetration into the mucus) in ...
12
Phenotypic comparison of Pseudomonas aeruginosa strains isolated from a variety of clinical sites
... Elevated levels of elastase were demonstrated in strains isolated froni acute lung infections, phospholipase C levels were elevated in urinary tract and blood isolates, exotoxin A levels[r] ...
5
Pyocyanin-induced mucin production is associated with redox modification of FOXA2
... Importantly, we have shown that PCN is important for both acute and chronic lung infections [30,31]. GCHM, excessive mucus secretion and defective mucociliary clearance, airway obstruction, bacterial ...
14
Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug resistant Gram negative bacteria in patients without cystic fibrosis
... treat lung infections with P aeruginosa ...of lung infec- tions and subsequently the decline in lung function among patients with cystic fibrosis ...
7
Morbidity and mortality related to pneumonia and TRACHEOBRONCHITIS in ICU after lung transplantation
... and Lung Transplantation Infectious Diseases Council working group defined proven pneumonia in cardiothoracic transplant recipients on the basis of clin- ical, radiologic and laboratory ...
9
Immunology of fibrotic lung disease: managing infections whilst preventing autoimmunity?
... Interstitial lung disease (ILD) and lung fibrosis are characterized by different grades of fibrosis and ...bacterial infections can cause ILD, although not usually in the form of usual interstitial ...
7
Costs and health care resource utilization among chronic obstructive pulmonary disease patients with newly acquired pneumonia
... Our results should be viewed in light of a number of limitations. First, due to the use of an administrative claims database, errors in reporting or missing data could have occurred using the ICD-9-CM codes for ...
8