Lung inflammation
In vivo monitoring of lung inflammation in CFTR deficient mice
... airway inflammation in CF is important for initiating the anti-inflammatory treatment and monitor- ing its ...models, inflammation is induced by instillation of bacterial products with pro-inflammatory ...
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Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation
... allergic lung inflammation, a mouse model for asthma, by reversing the ratio of effector T cells to Tregs in the lung, suppressing IL-13 and Th2 cytokine production, and blocking eosino- phil ...
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Interferon β attenuates lung inflammation following experimental subarachnoid hemorrhage
... The major finding of our study was that IFN- b treat- ment strongly attenuates the SAH mediated pulmonary inflammation. The decreased influx of neutrophils in response to IFN- b administration was accompanied by ...
6
Suppression of lung inflammation in an LPS induced acute lung injury model by the fruit hull of Gleditsia sinensis
... suppressing lung inflammation, we took transgenic NF-κB reporter mice and measured bioluminescence from the chest of the mice intermittently for 24 ...induces lung inflammation (top ...on ...
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Yap/Taz regulate alveolar regeneration and resolution of lung inflammation
... in lung alveoli, followed by alveolar epithelial regeneration and resolution of lung ...the lung and were delayed in alveolar epithelial regeneration during bacterial ...of lung ...
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A role for B cells in organic dust induced lung inflammation
... against lung tissue antigens ...in lung inflammation and oxidative stress has been shown to induce autoantibodies such as anti- citrullinated protein antibody (ACPA) that are impli- cated in ...
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Lung inflammation following a single exposure to swine barn air
... induces lung inflammation and AHR ...alters lung susceptibility to secondary challenges with microbes or their components such as lipopolysaccharide ...
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Aminoguanidine affects systemic and lung inflammation induced by lipopolysaccharide in rats
... of lung injury, inflammation and oxidative stress are involved as the underlying patho- physiological ...alleviate lung injury ...acute lung injury ...rat lung injury ...
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Sepsis-induced lung inflammation is modulated by insulin
... Lung inflammation was examined 6 h after sepsis by measuring leucocyte infiltration, edema and PGE2 levels in the ...animals. Lung edema was evaluated as increased protein concentration in the ...
8
Allergic lung inflammation promotes atherosclerosis in apolipoprotein E-deficient mice
... allergic inflammation increased atherosclerotic lesion sizes in the aortic root, along with increased lesion macrophages, increased splenic Th17 and Th2 cells, and reduced splenic regulatory T cells, without ...
22
Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury
... endotoxin are responsible for the enhanced inflamma- tory response of ALI and ARDS [3]. The LPS- induced mouse model of ALI is associated with increased neu- trophilic lung inflammation and endothelial ...
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The effects of Gamijinhae tang on elastase/lipopolysaccharide induced lung inflammation in an animal model of acute lung injury
... and lung inflammation ...diabetes, inflammation and neurodegenerative disease ...treat inflammation, cancer, bacterial and viral infections of the respiratory and gastrointestinal tracts ...
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Fipronil induces lung inflammation in vivo and cell death in vitro
... Lung inflammation is regulated through activation of innate immune system comprised of Toll-like receptors such as TLR4 and TLR9 that bind, respectively, to lipo- polysaccharides and CpG molecules ...
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Regulation of alveolar macrophage death in acute lung inflammation
... pulmonary infiltrates, hypoxemia, and injury to both the vascular endothelium and lung alveolar epithelium. Al- veolar macrophages (AM) account for approximately 95% of airspace leukocytes [15], and through the ...
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Lung inflammation caused by inhaled toxicants: a review
... Abstract: Exposure of the lungs to airborne toxicants from different sources in the environment may lead to acute and chronic pulmonary or even systemic inflammation. Cigarette smoke is the leading cause of ...
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The molecular fingerprint of lung inflammation after blunt chest trauma
... acute lung injury (ALI) progression and is known to increase ...that lung contusion is the major contributor to post- traumatic inflammation even in combined injury and in the presence of hemorrhagic ...
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The role of toll-like receptors in acute and chronic lung inflammation
... [113]. A detailed analysis showed that these responses were dependent on bacterial flagellin and TLR5 expres- sion. Peripheral blood mononuclear cells from CF patients also responded more vigorously to stimulation with ...
14
The role of PPARγ in carbon nanotube-elicited granulomatous lung inflammation
... in lung tissue and induce granu- lomatous changes (reviewed in ...human lung in response to a wide spectrum of environmental stimuli including intracellular pathogens, inert materials, and organic ...
10
Role of TNF-α in lung tight junction alteration in mouse model of acute lung inflammation
... v). After deparaffinization, for Claudin-2, Claudin-4, Clau- din-5, ZO-I and β -catenin detection, slices were treated with protease (type XIV, Sigma) (2 mg/ml) and for 10 min at 37°C. Detection of BCL-2 and Bax was ...
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Persistence of lung inflammation and lung cytokines with high-resolution CT abnormalities during recovery from SARS
... Each lung zone (total of 6 lung zones) was assigned a score, modified from previously described [9], based on the following: 0 when no involve- ment, 1 when <25% involvement, 2 when 25 <50% ...
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