lung injury
Biomarkers of acute lung injury: worth their salt?
... of lung injury and lower levels of lung derived inflammatory cytokines ...tissue injury and VALI should be devel- oped and incentive for this will be greatly increased as novel therapeutics ...
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The role of high airway pressure and dynamic strain on ventilator-induced lung injury in a heterogeneous acute lung injury model
... Severe systemic inflammation and shock can result in the development of acute respiratory distress syndrome (ARDS), which remains a serious clinical problem associated with an unacceptably high mortality [1]. Currently, ...
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Heparin-binding protein in ventilator-induced lung injury
... cause injury to the lungs. The lung injury is caused by not only high pressure and mechanical forces but also by inflammatory processes that are not fully ...the lung injury associated ...
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Acute lung injury Pathogenesis of intraalveolar fibrosis
... acute lung injury, interstitial mesenchymal cells migrate into the airspace where they replicate and deposit connective ...diffuse lung injury (n = 26) underwent bronchoalveolar ...without ...
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Transfusion related acute lung injury-TRALI: a review
... acute lung injury and absence of signs suggesting cardiogenic origin of pulmonary ...acute lung injury secondary to other etiologies, severe cases require endotracheal intubation and ...
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The proteomics of lung injury in childhood: challenges and opportunities
... pediatric lung injury unique challenges and opportunities ...of lung tissue provides an opportunity to directly study the proteome associated with lung injury and repair, however ...
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Vildagliptin induced acute lung injury: a case report
... Background: Dipeptidyl peptidase-4 inhibitors are a class of oral hypoglycemic drugs and are used widely to treat type 2 diabetes mellitus in many countries. Adverse effects include nasopharyngitis, headache, elevated ...
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PO2 oscillations induce lung injury and inflammation
... of lung injury has been proposed to capture the pathological hallmarks of early acute lung injury (ALI), as defined by diffuse alveolar ...endothelial injury and activation of the ...
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TGF β is a critical mediator of acute lung injury
... of injury, while patients do not come to medical atten- tion until after the lung injury has ...of injury, targeting the integrin αvβ6, the process of inte- grin-mediated TGF- β activation or ...
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CXCR2 is critical for dsRNA-induced lung injury: relevance to viral lung infection
... in lung injury in dsRNA-treated lungs, we next identified which specific factors, such as chemokines, were responsible for neu- trophil ...in lung KC/CXCL1 mRNA levels as well as in protein levels ...
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CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury
... Acute lung injury (ALI), a syndrome of rapid-onset bilateral pulmo- nary infiltrates of noncardiac origin, is characterized by alveolar- capillary injury, inflammation with neutrophil accumulation, ...
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Extravascular lung water index improves the diagnostic accuracy of lung injury in patients with shock
... of lung injury? (2) How well do the different EVLW indices relate to ICU mortality? (3) By applying EVLW as a bedside test, can the chances of diagnosing lung injury be increased? We ...
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Contribution of Neutrophils to Acute Lung Injury
... acute lung injury (ALI) and its most severe form, acute respiratory distress syndrome (ARDS), remain unsolved problems of intensive care ...by lung edema due to increased permeability of the ...
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Mechanical ventilation using non injurious ventilation settings causes lung injury in the absence of pre existing lung injury in healthy mice
... Introduction Mechanical ventilation (MV) may cause ventilator- induced lung injury (VILI). Present models of VILI use exceptionally large tidal volumes, causing gross lung injury and ...
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Incidence and Outcomes of Pediatric Acute Lung Injury
... RESULTS: Thirty-nine children met the criteria for acute lung injury, resulting in a calculated incidence of 12.8 cases per 100 000 person- years. Severe sepsis (with pneumonia as the infection focus) was ...
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Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury
... binding over controls. This binding was blocked by the addition of an excess amount of nitrotyrosine and was absent when the nitrotyrosine antibody was replaced with nonimmune IgG. In additional experiments we ...
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Application of flexible bronchoscopy in inhalation lung injury
... inhalational injury in most of our patients would not have been ...identifying injury early, those patients’ with more advanced exposures can be closely observed, allowing quick clinical response to any ...
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Perioperative ARDS and lung injury: for anaesthesia and beyond
... induced lung injury include minimising alveolar damage through the reduced transfer of energy to at-risk lung ...of lung injury into a single ...
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Using a non-invasive assessment of lung injury in a murine model of acute lung injury
... assess lung function following IT-LPS we investigated how these parameters relate to quantitative markers of lung in fl ammation and ...the lung injury, in fl ammatory cell recruitment and ...
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Lung injury edema in dogs Influence of sympathetic ablation
... characterizes lung injury pulmonary edema and renders fluid balance in the injured lung especially sensitive to changes in hydrostatic ...injured lung. We produced lung injury ...
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