Lymphoblastic leukaemia
Investigation of TEL/AML1 and BCR/ABL Fusion Genes in Patients Affected by Acute Lymphoblastic Leukaemia Using Interphase in situ Hybridization
... acute lymphoblastic leukaemia (ALL), including thirty children and thirty adults were studied by the conventional cytogenetics and fluorescence in situ hybridization (FISH) ...
9
Hypereosinophilia in childhood acute lymphoblastic leukaemia at diagnosis: report of 2 cases and review of the literature
... acute lymphoblastic leukaemia (ALL) and hypereosinophilia represents a distinct clinico-patho- logical entity [2-4], although rarely described in childhood [2,5,6], with 44 paediatric cases reported to date ...
5
Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10p21.2.
... Despite high-hyperdiploid acute lymphoblastic leukaemia (HD-ALL) being the most common subgroup of paediatric ALL, its aetiology remains unknown. Genome-wide association studies have demonstrated ...
9
Study of fingerprints in children under 15 years of age with acute lymphoblastic leukaemia
... of leukaemia will also be excluded from this ...acute lymphoblastic leukaemia below the age of 15years attending to Indo-American Cancer Institute and Little stars children hospital, Hyderabad will ...
5
French “real life” experience of clofarabine in children with refractory or relapsed acute lymphoblastic leukaemia
... Acute lymphoblastic leukaemia (ALL) is the most com- mon form of cancer in children, responsible for approxi- mately 30 percent of all childhood malignancies. Despite substantial improvements in the ...
8
Third-generation CD28/4-1BB chimeric antigen receptor T cells for chemotherapy relapsed or refractory acute lymphoblastic leukaemia: a non-randomised, open-label phase I trial protocol
... Introduction: There is no curative treatment available for patients with chemotherapy relapsed or refractory CD19+ B cells-derived acute lymphoblastic leukaemia (r/r B-ALL). Although CD19-targeting second- ...
7
Osteonecrosis in patients with acute lymphoblastic leukaemia: a national questionnaire study
... Downloaded from http://bmjpaedsopen.bmj.com/ on April 16, 2018 - Published by group.bmj.com Osteonecrosis in patients with acute lymphoblastic leukaemia: a national questionnaire study N[r] ...
8
A causal mechanism for childhood acute lymphoblastic leukaemia.
... In this Review, I present evidence supporting a multi-factorial causation of childhood acute lymphoblastic leukaemia (ALL), a major subtype of paediatric cancer. ALL evolves in two discrete steps. First, in ...
44
Effect of dexamethasone on quality of life in children with acute lymphoblastic leukaemia: a prospective observational study
... Acute Lymphoblastic Leukaemia (ALL) is the most com- mon form of childhood cancer. Over the past decades sur- vival following treatment for childhood ALL has improved substantially, now reaching about 80%. ...
8
Longitudinal assessment of nutritional status and its effects on the outcome of children completed treatment for Acute Lymphoblastic Leukaemia.
... Acute Lymphoblastic Leukaemia (ALL) is the most common cancer in children and it accounts for 25% of all childhood malignancies 4 .Survival rates of ALL has improved dramatically since 1980. Improvement in ...
152
Acute disseminated encephalomyelitis mimicking late CNS relapse of acute lymphoblastic leukaemia: case report
... Case presentation: A 13-year old girl presented with a severe acute myelopathy and encephalopathy. She was in prolonged remission from a central nervous system and bone marrow relapse of an acute lymphoblastic ...
5
Determination of the DNA repair pathways utilised by acute lymphoblastic leukaemia cells following daunorubicin treatment
... Factors influencing choice between NHEJ and HR are still unclear as many factors influence these processes including MRN complex, cell cycle checkpoints, and DNA-DSB effector proteins [14]. The aim of this study was to ...
5
The Role of MicroRNA in Paediatric Acute Lymphoblastic Leukaemia: Challenges for Diagnosis and Therapy.
... Acute lymphoblastic leukaemia (ALL) is the most common cancer of ...90%, leukaemia remains one of the leading causes of death from ...childhood leukaemia, focussing primarily on their use as ...
15
Understanding Acute Lymphoblastic Leukaemia
... It is important to remember that you may not be suitable for it. The type of leukaemia, your age, medical history and viral status can affect your suitability. Your doctor will arrange for you to have a blood test ...
41
Osteonecrosis in patients with acute lymphoblastic leukaemia: a national questionnaire study
... Age and ethnicity were found to be the most significant risk factors for development of ON, with Asian patients and patients aged 10–20 years at diagnosis of ALL at greatest risk.. Th[r] ...
7
Cytogenetic and molecular aberrations in childhood B lineage acute lymphoblastic leukaemia
... Acute Lymphoblastic Leukemia (ALL) is a common hematological malignancy in children and is characterized by genetic changes such as mutations and chromosomal ...
5
Nutritional Assessment and Serum Zinc Level in Children with Acute Lymphoblastic Leukaemia
... malnutrition in their children with newly diagnosed leukaemia. They found that 45 children enrolled in the study only 5(12.1%) children were malnourished. Three patients had a weight-for-height score of less than ...
5
The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia.
... the leukaemia initiating or so called ‘ cancer stem-cell ’ compartment providing insight in to genetic driver stability and evolutionary pressures on clonal ...the leukaemia initiating cell ...
10
Prospective evaluation of quality of life in children treated in UKALL 2003 for acute lymphoblastic leukaemia: A cohort study
... Specifically, the following were determined i generic HRQoL compared with population norms; ii changes in generic and disease-specific HRQoL over time, depending on child age, gender and[r] ...
16
Chromosome 6q16-21 deletions in acute lymphoblastic leukaemia
... In leukaemia lymphoma cell lines with MSI, frameshift mutations were most frequently detected in the BAX gene (82%), while the MSH3, MSH6, TGF-p type II receptor, IGF-IIR genes were less frequently mutated ...
234