Lymphocyte Activation
Lymphocyte Sub-populations and Lymphocyte Activation Markers in Pulmonary TB Patients
... for lymphocyte sub-populations as CD3, CD4, CD8, CD4/CD8 ratio, CD19, CD16+56, and for Lymphocyte activation markers including CD25, CD69 and ...
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Role of Nijmegen Breakage Syndrome Protein in Specific T-Lymphocyte Activation Pathways
... in lymphocyte subpopulations, peripheral blood mononuclear cell (PBMC) responses to a complete panel of mitogens that analyze the different lymphocyte activation path- ways (T-cell function, B-cell ...
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Morbilliviruses Use Signaling Lymphocyte Activation Molecules (CD150) as Cellular Receptors
... Morbilliviruses comprise measles virus, canine distemper virus, rinderpest virus, and several other viruses that cause devastating human and animal diseases accompanied by severe immunosuppression and lympho- penia. ...
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Inhibition of T lymphocyte activation in mice heterozygous for loss of the IMPDH II gene
... during lymphocyte activation via CD3 and CD28 costimulation is dependent on increased synthesis through both the de novo and salvage ...lowing activation via the T-cell receptor and CD28 sig- ...
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Bacterial toxins affect early events of T lymphocyte activation
... phosphates production did not result from inhibition of baseline incorporation of inositol into phosphoinositide substrates of phospholipase C. These studies underline the complexity of toxin effects on cellular systems ...
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Early events of human T lymphocyte activation are associated with type I protein kinase A activity
... T lymphocyte activation have not been clearly elucidated, we tested the hypothesis that very early events of normal human T lymphocyte activation are mediated by the PKA-I and/or ...
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Evidence that calcineurin is rate limiting for primary human lymphocyte activation
... While the qualitative role of CN inhibition in the effects of CsA on T lymphocyte activation is clear in vitro, the actual ef- fect of CN inhibitors in vivo is less clear. The peripheral blood leukocytes ...
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Ca2+ signals during early lymphocyte activation in carp Cyprinus carpio L
... In mammals, lymphocyte activation or inhibition results from a multitude of immune and non-immune signals. Positive and negative signals evoke a delicate interplay of signal transduction pathways in the ...
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Recent developments in lymphocyte activation: linking kinases to downstream signaling events
... of lymphocyte antigen receptors provided a convenient starting point for investigators to begin to identify signaling intermediates in ...novel lymphocyte-specific proteins are substrates of these PTKs and ...
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Requirements for lymphocyte activation by unusual strains of simian immunodeficiency virus.
... prior lymphocyte activation and without the addition of exogenous interleukin-2, caused extensive lymphocyte activation in these cultures, and produced an acute disease in rhesus and pigtail ...
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Direct effects of HP Acthar Gel® on human B lymphocyte activation in vitro
... During B-lymphocyte activation, the process of im- munoglobulin class switching is known to be dependent on cellular proliferation [22]. We therefore examined whether Acthar altered IL-4/CD40L-induced ...
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Suppression of ovine lymphocyte activation by Teladorsagia circumcincta larval excretory-secretory products
... Helminth infections are a major constraint to livestock production worldwide and represent a major challenge to continued food security. The parasitic nematodes that colonize the gastrointestinal tract of ruminants cause ...
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Modern fluorescent techniques to investigate the mechanisms of lymphocyte activation
... activation markers CD69, CD71 and proliferation reporter. Thus, at least 20 separate fluorescent sig - nals are needed to monitor the activation events in individual cells. Recently, there appeared ...
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Association of Selected Phenotypic Markers of Lymphocyte Activation and Differentiation with Perinatal Human Immunodeficiency Virus Transmission and Infant Infection
... of lymphocyte activation and mem- ory according to treatment group, maternal HIV transmission status, and infant HIV infection ...selected lymphocyte immunophe- notypic markers and the overall ...
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A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 nef alleles in lymphocyte activation.
... of activation markers, increased tyrosine phosphorylation, and increased activation of NF-kB ...rosine-based activation motifs; the presence of this sequence in nef allows for high-level virus ...
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Markers of B lymphocyte activation are elevated in patients with early rheumatoid arthritis and correlated with disease activity in the ESPOIR cohort
... B-lymphocyte activation are higher in early RA than in ...B-cell activation were nonetheless observed in patients with UA, including BAFF levels that were higher than in healthy donors, elevated IgG ...
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Mechanisms of Lymphocyte Activation: THE ROLE OF SUPPRESSOR CELLS IN THE PROLIFERATIVE RESPONSES OF CHRONIC LYMPHATIC LEUKEMIA LYMPHOCYTES
... to lymphocyte membrane receptors at equilibrium generated similar curvilinear Scatchard plots in 20 patients with bursa-derived (B)-cell-type chronic lymphatic leukemia (CLL) and 15 ...
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In Vivo T-Lymphocyte Activation and Transient Reduction of Viral Replication in Macaques Infected with Simian Immunodeficiency Virus
... SEB-induced stimulation of IFN- ␥ -secreting T cells coin- cided with the short-term control of SIVmac infection. We then sought to confirm that the reduction in SIV replication seen early after BCG coinfection was ...
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Lymphocyte Activation during Acute Simian/Human Immunodeficiency Virus SHIV89.6PD Infection in Macaques
... animal, AQ73, received the same inoculum but was negative for infection by all laboratory tests and did not even show transient viremia. By establishing a new infected-animal co- hort, we were able to obtain fresh PBMC ...
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Traumatic brain injury causes selective, CD74-dependent peripheral lymphocyte activation that exacerbates neurodegeneration
... Efficient antigen processing and presentation via the major histocompatibility complex II (MHCII) pathway in APCs, including macrophages, microglia, dendritic cells, B cells, and γδ T cells, facilitates the transition ...
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