lymphocyte function
Polymorphism of lymphocyte function associated antigen 1 demonstrated by a lupus patient's alloantiserum
... We have found a human serum, E27, obtained from a multiply transfused patient with systemic lupus erythematosus, which immunoprecipitates the lymphocyte function associated antigen-1 (LFA-1). The ...
9
Differential Effects of Immunosuppressants on Lymphocyte Function
... T lymphocyte function were evaluated in guinea pigs following treatment with the “cycle-active” drugs, 6-mercaptopurine (6MP) and methotrexate, and the “non-cycle-active” alkylating agent, ...
8
Glucocorticoids Administered In Vivo Inhibit Human Suppressor T Lymphocyte Function and Diminish B Lymphocyte Responsiveness in In Vitro Immunoglobulin Synthesis
... T lymphocyte activity, observed with normal T lymphocytes at high T to B cell ratios, was absent from the post-steroid T ...T lymphocyte function was not due to the presence of excess help as ...
10
Impaired Lymphocyte Function in Aged Humans
... observed lymphocyte reactivity could not be attributed to differences in culture conditions required for maximal transformation of lymphocytes from old or young ...
7
Partial Purine Nucleoside Phosphorylase Deficiency: STUDIES OF LYMPHOCYTE FUNCTION
... significantly reduced lymphocyte proliferative responses to nonspecific mitogens, specific antigen, and allogeneic cells. E-rosetting cells were present but reduced in number (20.0% and 31.5%). Serum ...
11
Characterization of a non T, non B human lymphocyte (L cell) with use of monoclonal antibodies Its regulatory role in B lymphocyte function
... These studies investigate the role of L lymphocytes in regulating terminal B lymphocyte differentiation. L cells have abundant Fc IgG receptors and comprise 10--15% of human peripheral blood mononuclear cells ...
9
Changes in lymphocyte function and subset counts in cats with spontaneous chronic kidney disease
... Lymphopenia per se does not explain the immune dysfunction described in uremic patients. T cells represent a major component of the adaptive im- mune system and play a central role in cell-medi- ated immunity. Th ...
7
Inhibition of anti tuberculosis T lymphocyte function with tumour necrosis factor antagonists
... responses The effect of 14-week treatment with a TNF antagonist on the immune response against purified protein derivative PPD was determined in patients without a previous or latent tub[r] ...
15
Effect of transfer factor on lymphocyte function in anergic patients
... Lymphocytes from recipients produced MIF when cultured with antigens that evoked positive delayed skin tests. Only one patient developed antigen-induced lymphocyte transformation and this response occurred only ...
12
Abnormal cytolytic activity of lymphocyte function associated antigen 1 deficient human cytolytic T lymphocyte clones
... unchanged with prolonged culture, and identical on 14 different CTL clones. The function of the LFA-1 molecule was addressed using the LFA-1-deficient CTL clones and LFA-1- deficient lymphoid target cells. The ...
6
Shipment Impairs Lymphocyte Proliferative Responses to Microbial Antigens
... Lymphocyte proliferation assays (LPAs) are widely used to assess T-lymphocyte function of patients with human immunodeficiency virus infection and other primary and secondary immunodeficiency ...
5
NF κB–inducing kinase controls lymphocyte and osteoclast activities in inflammatory arthritis
... NF-kB is an important component of both autoimmunity and bone destruction in RA. NF- kB–inducing kinase (NIK) is a key mediator of the alternative arm of the NF-kB pathway, which is characterized by the nuclear ...
8
Detection of Antilymphocyte Antibody with Two Color Method in Systemic Lupus Erythematosus and Its Heterogeneous Specificities against Human T Cell Subsets
... Suppressor function of peripheral blood mononuclear cells in normal individuals and in patients with systemic lupus erythematosus.. Loss of suppressor T-lymphocyte function in patients w[r] ...
9
Differential effects of palmitoleic acid on human lymphocyte proliferation and function
... and IL-10 induced a Th2 response, which one would be specific for reactions related with hypersensitivity. Therefore, reduction in Th1 and Th17A cytokine release by the PA treatment was not associated with Th2 response. ...
11
Prognostic value of pre operative inflammatory response biomarkers in gastric cancer patients and the construction of a predictive model
... arginase, and ROS [43], leading to depletion of lymphocyte- mediated immune response. This can explain why in- creased NLR may act as an independently prognostic factor for CSS due to elevated neutrophil and ...
16
Download Download PDF
... - lymphocyte ratio had association with malignant ovarian tumor ...- lymphocyte ratio and the process of cancer, including cancer staging, prognosis and response to ...- lymphocyte and neutrophil - ...
5
The clinical use of pretreatment NLR, PLR, and LMR in patients with esophageal squamous cell carcinoma: evidence from a meta-analysis
... to lymphocyte ratio,” “neutrophil-to-lymphocyte ratio,” “neutrophil–lymphocyte ratio,” “neutrophil/lymphocyte ratio”) OR “PLR” (“platelet lymphocyte ratio,” “platelet–lymphocyte ...
13
Density of CD8+ lymphocytes in biopsy samples combined with the circulating lymphocyte ratio predicts pathologic complete response to chemoradiotherapy for rectal cancer
... neutrophil– lymphocyte ratio (NLR) or the lymphocyte ratio (LYMR) and tumor-infiltrating lymphocyte (TIL) count, respectively, have been suggested as predictors of the tumor response to neoadjuvant ...
8
Preoperative lymphocyte-to-monocyte ratio represents a superior predictor compared with neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios for colorectal liver-only metastases survival
... operative lymphocyte-to-monocyte ratio (LMR), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) in patients with colorectal liver-only metastases (CLOM) undergoing ...
11
PubMedCentral-PMC5391224.pdf
... GA function measures such as physical function, IADL, and Timed Up and Go (TUG) ...physical function scale is a subscale of the Medical Outcomes Study (MOS) Physical ...
12