Lysosomal Enzymes
Herpes simplex virus and human cytomegalovirus replication in WI-38 cells. III. Cytochemical localization of lysosomal enzymes in infected cells.
... Cytochemical Localization of Lysosomal Enzymes in Infected Cells JANET DUYCKINCK SMITH"* AND ETIENNE DE HARVEN2 Department of Anatomy, The Medical College of Pennsylvania and Hospital, P[r] ...
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Increased Activity of Lysosomal Enzymes in the Peritoneal Fluid of Bacterial Peritonitis
... the lysosomal enzymes -galactosi- dase,  -glucuronidase, and ␣ -mannosidase is signif- icantly increased in the peritoneal fluid of patients with bacterial ...these enzymes in the peritoneal fluid ...
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Apical secretion of lysosomal enzymes in rabbit pancreas occurs via a secretagogue regulated pathway and is increased after pancreatic duct obstruction
... and lysosomal enzymes, suggesting that they are discharged from the same presecretory compartment (zymogen ...granules). Lysosomal enzymes appear to enter that compartment as a result of ...
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VARIATIONS IN LYSOSOMAL ENZYMES OF UTERINE EPITHELIAL/STROMAL CELLS DURING PRE IMPLANTATION PERIOD IN RAT UNDER CDRI 85/287
... In response to the ovarian secretion of progesterone and estrogen during early gestation period, the mammalian uterus, especially epithelial cells develop the capacity to perform several cellular functions vital to ...
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Influence of myrtenal on the levels of surface glycoproteins, nucleic acids, and lysosomal enzymes against 1, 2-dimethyl hydrazine-induced experimental colon carcinoma
... acids, lysosomal enzymes, and histopathological ...acids, lysosomal enzymes, and also significant alterations in tissues of cancer-bearing animals with histological ...on lysosomal ...
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Multiple Domains of GlcNAc-1-phosphotransferase Mediate Recognition of Lysosomal Enzymes
... of phosphorylation. As shown in Fig. 6B, the consequences of deleting Notch 1, Notch 2, or the DMAP interaction domain on the generation of the Man-6-P residues on ␣ -GalA and ␣ - and  -Man as measured by this technique ...
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Cytochemical localization of lysosomal enzymes in rat megakaryocytes and platelets
... lysosmal enzymes during the "platelet release reaction" early in clot ...two lysosomal enzymes, arylsulfatase and acid phosphatase, in megakaryocytes and platelets of normal and ...
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METACHROMASIA AND ASSAY FOR LYSOSOMAL ENZYMES IN SKIN FIBROBLASTS CULTURED FROM PATIENTS WITH CYSTIC FIBROSIS AND CONTROLS
... FIBROBLASTS CULTURED FROM PATIENTS WITH CYSTIC FIBROSIS AND METACHROMASIA AND ASSAY FOR LYSOSOMAL ENZYMES IN SKIN. Services[r] ...
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The metabolism of Tay Sachs ganglioside: catabolic studies with lysosomal enzymes from normal and Tay Sachs brain tissue
... The catabolism of Tay-Sachs ganglioside, N-acetylgalactosaminyl- (N-acetylneuraminosyl) -galactosylglucosylceramide, has been studied in lysosomal preparations from normal human brain and brain obtained at biopsy ...
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Influence of methylprednisolone of the sequential redistribution of cathepsin D and other lysosomal enzymes during myocardial ischemia in rabbits
... In hearts untreated with methylprednisolone, the proportions of total cathepsin D, glucosaminidase, and acid phosphatase activities that were recovered in the nonsedimentable fraction we[r] ...
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Trafficking of lysosomal enzymes in normal and disease states
... While the M-6-P recognition pathway is clearly important in lysosomal enzyme targeting, there must be mechanisms for localizing acid hydrolases to lysosomes independent of this recogniti[r] ...
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A plasma protease which is expressed during supramaximal stimulation causes in vitro subcellular redistribution of lysosomal enzymes in rat exocrine pancreas
... and lysosomal hydrolases are segregated from each other and differentially transported to their respective membrane- bound intracellular organelles in the pancreas have been noted to be disturbed during the early ...
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Quantitative Proteome Analysis of Mouse Liver Lysosomes Provides Evidence for Mannose 6-phosphate-independent Targeting Mechanisms of Acid Hydrolases in Mucolipidosis II
... of lysosomal proteins (12, ...to lysosomal storage diseases, mucolipidosis type II (ML II also called I-cell disease) and III (ML III) ...soluble lysosomal proteins in ML II and ML III, respectively, ...
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Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking
... of lysosomal enzymes in the Golgi apparatus for their targeted trans- port to the lysosome ...the lysosomal storage diseases ML-II/III ...circulating lysosomal enzyme ...the lysosomal ...
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ANTICANCER EFFECT OF METHANOLIC EXTRACT OF ANNONA SQUAMOSA ON MAMMARY CARCINOMA IN RATS WITH REFERENCE TO GLYCOPROTEIN COMPONENTS, LYSOSOMAL, AND MARKER ENZYMES
... hydrolytic enzymes that are capable of digesting the macromolecules such as polysaccharides, nucleic acid, and lipids ...of lysosomal enzymes which may have local and systemic effects when released ...
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EVALUATION OF MIXTURES OF AQUEOUS EXTRACT OF PSEUDOCEDRELA KOTSCHYI AND BOSWELLIA DALZEILII AS INTERACTING PRODUCTS IN REGULATION OF PHAGOCYTOSIS AND LYMPHOCYTES PROLIFERATION
... The present results are in-agreement with those of several auteurs that reported the interactions of the extract compounds in modulation of the immune response 11 . From the present experiments it is very much clear that ...
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Selective loss of glucocerebrosidase activity in sporadic Parkinson’s disease and dementia with Lewy bodies
... other lysosomal enzymes consid- ered in this study, we found a significant reduction of α-fucosidase activity in the frontal cortex of PD patients compared to control subjects, while in DLB the reduction ...
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Lysosomal processing of progranulin
... Deletion of cathepsin L, K or Z had no effect on PGRN processing, while ablation of either cathepsin B or D re- sulted in ~50% reduction in the ratio of processed PGRN peptides versus full-length PGRN (Fig. 3a and b). ...
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Determination of frequencies of alleles, associated with the pseudodeficiency of lysosomal hydrolases, in population of Ukraine
... of lysosomal enzymes pseudodeficiency is rather high incidence in the total ...of lysosomal storage disorders in a spe- cific population, the frequency of alleles of pseudo- deficiency of ...
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Type 1 Diabetes: Urinary Proteomics and Protein Network Analysis Support Perturbation of Lysosomal Function
... Using Cytoscape [55] proteins interacting with those that had a fold change of more than +/-1.2 were retrieved to generate a protein network in silico. This network consisted of 860 nodes with 940 edges (Supplementary ...
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