M1 protein
Influenza Virus Assembly: Effect of Influenza Virus Glycoproteins on the Membrane Association of M1 Protein
... matrix protein (M1), a critical protein required for virus assembly and budding, is presumed to interact with viral glycoproteins on the outer side and viral ribonucleoprotein on the inner ...of ...
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Mutations in the Influenza A Virus M1 Protein Enhance Virus Budding To Complement Lethal Mutations in the M2 Cytoplasmic Tail
... the M1 ORF (Table 1). These M1 suppressor mutations are located at 7 distinct positions of the protein and are present in the N-terminal, middle, and C-terminal regions of the protein (yellow ...
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Tyrosine 132 Phosphorylation of Influenza A Virus M1 Protein Is Crucial for Virus Replication by Controlling the Nuclear Import of M1
... are protein tyrosine kinases ...of M1 during virus replication, like the effect of the loss of phosphorylation of Y132 (as has been ...with M1 and thus was considered necessary for virus replication ...
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Functional and antigenic domains of the matrix (M1) protein of influenza A virus.
... Comparative binding of M1 protein or its cleaved peptides to DPPC small unilamellar vesicles and effect of monoclonal antibodies Protein or peptidea MAb Fab presentb % Reconstitution Int[r] ...
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A Mutation on Influenza C Virus M1 Protein Affects Virion Morphology by Altering the Membrane Affinity of the Protein
... Membrane flotation analyses of infected and transfected cells. As shown above, residue 24 of the M1 protein is involved in the morphology of influenza C viruses. To detect any dif- ferences between the two ...
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Distinct Domains of the Influenza A Virus M2 Protein Cytoplasmic Tail Mediate Binding to the M1 Protein and Facilitate Infectious Virus Production
... and M1 during virus assembly (5, 15, 25, 57, ...the M1 protein was critical for infectious virus production, expression vectors containing genetic fusions be- tween M2 and M1 as well as ...
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Streptococcal M1 protein induces hyporesponsiveness and cytokine release from human arteries in a fibrinogen-dependent manner: a translational study
... example M1 protein forms complexes with fibrinogen, which cause neutrophils to degranulate and release heparin-binding pro- tein (HBP) ...[11]. M1 protein also produces a direct vascular ...
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Role of the Influenza Virus M1 Protein in Nuclear Export of Viral Ribonucleoproteins
... export protein, or NEP) is responsible for vRNP nuclear ex- port via its interaction with M1 ...a protein that allows full-length transcripts of the HIV genome to be exported from the nucleus ...
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The membrane (M1) protein of influenza virus occurs in two forms and is a phosphoprotein.
... Our preliminary efforts indicate that the phosphorylated tryptic peptide remains at the origin when the tryptic fragments are analyzed under the condi- Downloaded from http://jvi.asm.org[r] ...
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Effect of M1 protein and low pH on nuclear transport of influenza virus ribonucleoproteins.
... with M1 determines whether vRNPs are transported into or out of the ...with M1 is needed for vRNP export from the nucleus (25, ...that M1 dissociation is necessary for nuclear ...prevent M1 ...
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The Influenza Virus M2 Protein Cytoplasmic Tail Interacts with the M1 Protein and Influences Virus Assembly at the Site of Virus Budding
... of M1, M2, and HA, the spatial distribution of viral proteins in planar sheets of plasma membrane prepared from virus-infected cells was ...membrane protein distribution upon activation of T cells ...
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Growth control of influenza A virus by M1 protein: analysis of transfectant viruses carrying the chimeric M gene.
... To determine which of the two M proteins, Ml or M2, is responsible for the growth rate control of influenza virus, attempts were made to generate recombinant viruses carrying the chimeri[r] ...
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Influenza virus NS1 protein stimulates translation of the M1 protein.
... M-CAT RNA, which contains the chloramphenicol acetyltransferase CAT reporter gene and the terminal noncoding sequence of segment 7 coding for the Ml and M2 proteins, was ribonucleoprotei[r] ...
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Formation of Wild-Type and Chimeric Influenza Virus-Like Particles following Simultaneous Expression of Only Four Structural Proteins
... matrix protein (M1) localizes in nuclei as well as at discrete areas of the plasma membrane where HA and NA colocalize at the cell ...that M1, HA, and NA were secreted into the culture ...of ...
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The Highly Conserved Arginine Residues at Positions 76 through 78 of Influenza A Virus Matrix Protein M1 Play an Important Role in Viral Replication by Affecting the Intracellular Localization of M1
... virus M1 is replaced with a lysine at the same position in the M1 of influenza B virus ...construct protein expression plasmids for M1 in which lysine (K, conservative), alanine (A), or ...
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Attenuation of Equine Influenza Viruses through Truncations of the NS1 Protein
... total protein was loaded onto a 12% SDS- polyacrylamide ...NS1 protein with a rabbit polyclonal antibody generated against the first 73 amino acids of the ...viral M1 protein was also included ...
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Virus-Like Particle Vaccine Confers Protection against a Lethal Newcastle Disease Virus Challenge in Chickens and Allows a Strategy of Differentiating Infected from Vaccinated Animals
... In this study, we developed Newcastle disease virus (NDV) virus-like particles (VLPs) expressing NDV fusion (F) protein along with influenza virus matrix 1 (M1) protein using the insect cell ...
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pH-Dependent Formation and Disintegration of the Influenza A Virus Protein Scaffold To Provide Tension for Membrane Fusion
... of M1 protein on the one side of a BLM changed the difference in boundary potentials across the lipid bilayer, which was measured by the IFC tech- nique ...membrane. M1 protein was washed from ...
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Association of Influenza Virus Matrix Protein with Ribonucleoproteins
... Wt M1 protein (M1-252) and substitution mutants (M101-SNLNS-105 and MC148S) with RNase A-treated RNP are shown in ...Wt M1 was only 35% relative to that with untreated RNP ...Wt M1 ...
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Transcription-inhibition and RNA-binding domains of influenza A virus matrix protein mapped with anti-idiotypic antibodies and synthetic peptides.
... The capacity of Ml protein to bind influenza virus RNA and the region of the Ml protein responsible for this binding were tested with virion proteins, purified M1 protein, and formic aci[r] ...
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